Role of the Lactide:Glycolide Ratio in PLGA Nanoparticle Stability and Release under Lysosomal Conditions for Enzyme Replacement Therapy of Lysosomal Storage Disorders

Autor: Maria del Moral, Maximilian Loeck, Eameema Muntimadugu, Guillem Vives, Vy Pham, Peter Pfeifer, Giuseppe Battaglia, Silvia Muro

Publikováno v: Journal of Functional Biomaterials, Vol 14, Iss 9, p 440 (2023)

Prior studies demonstrated that encapsulation in poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) enhanced the delivery of enzymes used for replacement therapy (ERT) of lysosomal storage disorders (LSDs). This study examined how the copolymer

Externí odkaz: https://doaj.org/article/cdebf2306601418baf97f97b042f81a0

Acknowledgement to Reviewers of Journal of Functional Biomaterials in 2019

Autor: Yang Hu, Kristy Welshhans, Ba Thuy Linh Nguyen, Sergey V. Dorozhkin, Jiranuwat Sapudom, Ming-Chia Li, Toni Ibrahim, Giuseppe Daprile, Sunil Kumar Boda, Alicja Kazek-Kęsik, Udayabhanu Jammalamadaka, Tz-Feng Lin, Maria Gomez-Lazaro, Ganesh Narayanan, Gianluca Turco, Hans-Jörg Meisel, Ludwig Erik Aguilar, David Eglin, Xiaoju Wang, Ellen Bruzell, Maohua Lin, Jingwei He, E. Scott Sills, Sara Bernardi, Marina Nisnevitch, Giuseppe Lo Giudice, Gabriella Lindberg, Houliang Tang, Edit Csapo, Tao Yang, Ana Dinca, Barbara Mulloy, Pasquale Marrazzo, David Donnermeyer, Ana M. Beltrán, Takashi Hoshiba, Wei Long Ng, Edward Chern, Rita Ambu, Vijaykumar Sutariya, Iman Yazdi, Yuta Otsuka, Jagannath Padmanabhan, Annika Kengelbach-Weigand, Sahar Mokhtari, Klara Magyari, Farshid Sefat, Gabriela Ciapetti, Kok Yong Chin, Mercedes Fernández-Arévalo, Ang-Chen Tsai, Loredana Incarnato, Florin Iordache, Csaba Hegedűs, Francesco Baino, Flavio Rizzolio, Antonio Scarano, Ewa Kijenska, Joanna Kolmas, Yi Zhang, Jacob Zeitani, Kinga Grzech-Leśniak, Steve Elder, Chao Peng, Lukasz Witek, Susanna Piluso, Kiran Chereddy, Jeffrey M. Ting, Yuchen Wang, Chih-Chen Hsieh, Jennifer Patterson, Laurence J. Walsh, Rebeca Illescas Illescas Montes, Carmen Alvarez-Lorenzo, Ilaria Cacciotti, Hanna Tölli, Martina Banchelli, Anna A. Okunkova, Catalin Amza, Franziska Schmidt, Bhavesh Kevadiya, Ravindranadh Koutavarapu, Yubin Zhou, Rubén Rabadán-Ros, Dragana Gabrić, Miyoung Lee, Alessandro Crisci, Daniel Chateigner, Marco Tallarico, Michael T. Koltz, Guofang Shen, Federica Fregnan, Blanca Ríos-Carrasco, Sudip Mukherjee, Chunju Gu, Nataraja Sekhar Yadavalli, Brandis Keller, Ana Figueiras, Nikolaos Bouropoulos, Katherine R. Hixon, Giuseppe Perale, Stefano Pagano, Manja Kurečič, Sachiko Iseki, Mike Barbeck, Pamela J. Walsh, Patricia Diaz-Rodriguez, Maria Helena Casimiro, Akira Tsuchiya, Maja Dutour Sikirić, Carlos Garcia-Gonzales, Christen J. Boyer, Mario Raspanti, Dinesh Gundapaneni, Giovanni Solitro, Poulami Majumder, Ali Paknahad, Carlos Miguel Marto, Vi Khanh Truong, Ramón Román-Doval, Jeffrey Banas, Yasuhiko Tabata, Maksym Pogorielov, Veronica Dodero, John W. Nicholson, Eameema Muntimadugu, Li Zhu, Laurent Metzinger, Saikat Nandi, Seung Yun Nam, Xanthe Strudwick, Zhitong Chen, Lu Yu, Yugang Huang, Francisco Javier Rodríguez-Lozano, Luis Rodríguez-Lorenzo, Anna Vilà, Eleonore Fröhlich, Morgan Hamon, Susumu Hama, Ana Messias, Christine Joly-Duhamel, Jamileh Shojaeiarani

Publikováno v: Journal of Functional Biomaterials, Vol 11, Iss 1, p 6 (2020)
Journal of Functional Biomaterials

The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not [...]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f541c5ceda87d4dfdfe3fcd13cdba03a
https://www.mdpi.com/2079-4983/11/1/6

CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel

Autor: Towseef Amin Rafeeqi, Eameema Muntimadugu, Rajendra Kumar, Shantikumar Saladi, Wahid Khan

Publikováno v: Colloids and Surfaces B: Biointerfaces. 143:532-546

This combinational therapy is mainly aimed for complete eradication of tumor by killing both cancer cells and cancer stem cells. Salinomycin (SLM) was targeted towards cancer stem cells whereas paclitaxel (PTX) was used to kill cancer cells. Drug loa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42c6171c37eebf231402be2a570da1e
https://doi.org/10.1016/j.colsurfb.2016.03.075

Exploring the Potential of Nanotherapeutics in Targeting Tumor Microenvironment for Cancer Therapy

Autor: Wahid Khan, Eameema Muntimadugu, Nagavendra Kommineni

Publikováno v: Pharmacological research. 126

Advanced research in the field of cancer biology clearly demonstrated the key role of tumor microenvironment (TME) in cancer development and metastasis particularly in solid tumors. Components of TME, being non-neoplastic in nature provide supportive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef2c6a7a9771c731d6bb014c79498e0
https://pubmed.ncbi.nlm.nih.gov/28511988

Co-delivery of rapamycin- and piperine-loaded polymeric nanoparticles for breast cancer treatment

Autor: Towseef Amin Rafeeqi, Abraham J. Domb, Eameema Muntimadugu, Sameer S. Katiyar, Wahid Khan

Publikováno v: Drug delivery. 23(7)

P-glycoprotein (P-gp) efflux is the major cause of multidrug resistance (MDR) in tumors when using anticancer drugs, moreover, poor bioavailability of few drugs is also due to P-gp efflux in the gut. Rapamycin (RPM) is in the clinical trials for brea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088c7e1218f690adf5f6ce2c10bf14a6
https://pubmed.ncbi.nlm.nih.gov/26036652