Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Eagle Sh Chu"'
Autor:
Jessie Qiaoyi Liang, Chun Ho Szeto, Harry C. Lau, Ying-Xuan Chen, Jun Yu, Sunny H. Wong, Eagle Sh Chu, Joseph J.Y. Sung, Jing-Yuan Fang
Publikováno v:
Journal of Gastroenterology and Hepatology
Background and Aim We have previously shown that fecal microbial markers might be useful for non‐invasive diagnosis of colorectal cancer (CRC) and adenoma. Here, we assessed the application of microbial DNA markers, as compared with and in combinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dd2d6f3a23326e7094f48040fc703b
https://pubmed.ncbi.nlm.nih.gov/32633422
https://pubmed.ncbi.nlm.nih.gov/32633422
Autor:
William K.K. Wu, Yunfei Zhou, Hong Wei, Liuyang Zhao, Eagle Sh Chu, Ka Fai To, Jun Yu, Risheng Zhao, Xiang Zhang, Olabisi Oluwabukola Coker, Joseph J.Y. Sung, Sunny H. Wong
Background:Large-scale meta-analysis of fecal shotgun metagenomic sequences revealed high abundance of Parvimonas micra in colorectal cancer (CRC) patients. We investigated the role of P. micra in colon tumorigenesis.Results: P. micra was significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8653ce3d2625690d33f2662a0067cc2
https://doi.org/10.21203/rs.3.rs-25974/v1
https://doi.org/10.21203/rs.3.rs-25974/v1
Autor:
Juqiang Han, Eagle Sh Chu, Yuemin Nan, Jinghua Du, Xiang Zhang, Jun Yu, Yanquan Zhang, Kwan Man
Publikováno v:
Theranostics
Mitochondrial dysfunction plays a crucial role in the development of non-alcoholic steatohepatitis (NASH). However, the regulator of mitochondrial dysfunction in the pathogenesis of NASH is still largely unclear. CXCR3 is an essential pro-inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffda56f534711a3c383b1a07c24506b6
https://doi.org/10.7150/thno.21400
https://doi.org/10.7150/thno.21400
Publikováno v:
SSRN Electronic Journal.
Background & Aims: The role of macrophages in fibrosing steatohepatitis is largely unclear. We characterized the origin and molecular mechanisms of macrophages and its targeted therapy in fibrosing steatohepatitis. Methods: Fibrosing steatohepatitis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3832bc99937359839c485c8ae40cb6cd
https://doi.org/10.2139/ssrn.3218694
https://doi.org/10.2139/ssrn.3218694
Autor:
Yangchao Chen, Xiaoxing Li, Chi Chun Wong, Ling Dong, Jia Wang, Jiayun Shen, Joseph J. Sung, Lixia Xu, Jun Yu, Eagle Sh Chu
Publikováno v:
Cancer letters. 355(2)
B cell CLL/lymphoma 6 member B (BCL6B) is a novel tumor suppressor silenced in human cancer. In this study, we investigated the functional role and underlying mechanisms of BCL6B in hepatocellular carcinoma (HCC). BCL6B was expressed in normal HCC ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b665d01c9535fefd95f1118b05f6f97a
https://pubmed.ncbi.nlm.nih.gov/25218345
https://pubmed.ncbi.nlm.nih.gov/25218345
Publikováno v:
Gastroenterology. 150:S1026
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45d184ba2ca0fb2b7e04552fafd2ef5f
https://doi.org/10.1016/s0016-5085(16)33473-4
https://doi.org/10.1016/s0016-5085(16)33473-4
Publikováno v:
Gastroenterology. 150:S1153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d120750d4ddd5e4ebdbf4bda040cf16b
https://doi.org/10.1016/s0016-5085(16)33893-8
https://doi.org/10.1016/s0016-5085(16)33893-8
Autor:
Alfred S. L. Cheng, Vincent Wai-Sun Wong, Chung Wah Wu, Eagle Sh Chu, Joseph J.Y. Sung, Cleo N.Y. Lam, Jun Yu, C W Lee
Publikováno v:
Gene therapy. 17(6)
Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a transcription factor that regulates lipid metabolism and inflammatory responses. Certain PPARgamma ligands improve nonalcoholic steatohepatitis (NASH). The role of PPARgamma itself in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31496aee45c40f4aa77181d1fc43c952
https://pubmed.ncbi.nlm.nih.gov/20376096
https://pubmed.ncbi.nlm.nih.gov/20376096
Publikováno v:
Gastroenterology. 146:S-957
tion of miR-122 underexpression with steatohepatitis. To our knowledge, this is the first report of underexpression of miR-370 in steatohepatitis. This result is mechanistically consistent with a previous study that showed upregulation of miR-122 by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::febaa25ecc0e6047be19c470994a2cce
https://doi.org/10.1016/s0016-5085(14)63484-3
https://doi.org/10.1016/s0016-5085(14)63484-3