Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Eagle S. H. Chu"'
Autor:
Jessie Qiaoyi Liang, Narcissus Teoh, Lixia Xu, Sharon Pok, Xiangchun Li, Eagle S. H. Chu, Jonathan Chiu, Ling Dong, Evi Arfianti, W. Geoffrey Haigh, Matthew M. Yeh, George N. Ioannou, Joseph J. Y. Sung, Geoffrey Farrell, Jun Yu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nonalcoholic steatohepatitis (NASH) and dietary cholesterol are risk factors for hepatocellular carcinoma (HCC). Here, the authors utilise mouse models to show that dietary cholesterol induces NASH by deregulating genes involved in metabolism, inflam
Externí odkaz:
https://doaj.org/article/f586a8b5cf4f4dbbb56141228ef1c3be
Autor:
Feiyu Shi, Gaixia Liu, Yufeng Lin, Cosmos liutao Guo, Jing Han, Eagle S. H. Chu, Chengxin Shi, Yaguang Li, Haowei Zhang, Chenhao Hu, Ruihan Liu, Shuixiang He, Gang Guo, Yinnan Chen, Xiang Zhang, Olabisi Oluwabukola Coker, Sunny Hei Wong, Jun Yu, Junjun She
Publikováno v:
Oncogene. 42:530-540
Appendectomy impacts the homeostasis of gut microbiome in patients. We aimed to study the role of appendectomy in colorectal cancer (CRC) risk through causing gut microbial dysbiosis. Population-based longitudinal study (cohort 1, n = 129,155) showed
Autor:
Chi Chun Wong, Xiaoyong Yang, Qunxiang Ong, Jun Yu, Rui Li, Eagle S. H. Chu, Joseph J.Y. Sung
Publikováno v:
Journal of Gastroenterology and Hepatology. 36:3477-3486
BACKGROUND AND AIM Protein O-GlcNAcylation is a critical post-translational modification regulating gene expression and fundamental cell functions. O-GlcNAc transferase (OGT) emerged as a key regulator of liver pathophysiology and disease. In this st
Autor:
Wing Yin, Cheng, Wei-Xin, Liu, Yanqiang, Ding, Guoping, Wang, Yu, Shi, Eagle S H, Chu, Sunny, Wong, Joseph J Y, Sung, Jun, Yu
Publikováno v:
Genomics, Proteomics & Bioinformatics.
The high host genetic background of tissue biopsies hinders the application of shotgun metagenomic sequencing in characterizing the tissue microbiota. We proposed an optimized method that removed host DNA from colon biopsies and examined the effect o
Autor:
Tong Li, Ying-Xuan Chen, Siew C. Ng, Jing-Yuan Fang, Francis K.L. Chan, Joseph J.Y. Sung, Jessie Qiaoyi Liang, Eagle S. H. Chu, Geicho Nakatsu, Sunny H. Wong, Chun Ho Szeto, Jun Yu, Tung On Yau
Publikováno v:
Gut. 69:1248-1257
ObjectiveThere is a need for early detection of colorectal cancer (CRC) at precancerous-stage adenoma. Here, we identified novel faecal bacterial markers for diagnosing adenoma.DesignThis study included 1012 subjects (274 CRC, 353 adenoma and 385 con
Autor:
Anthony W.H. Chan, Joseph J.Y. Sung, Francis K.L. Chan, Li Tong, Chun Ho Szeto, Olabisi Oluwabukola Coker, Eagle S. H. Chu, Xiaohang Long, Chi Chun Wong, Minne Y. Y. Go, Jun Yu
Publikováno v:
Nature Microbiology. 4:2319-2330
Emerging evidence implicates a role of the gut microbiota in colorectal cancer (CRC). Peptostreptococcus anaerobius (P. anaerobius) is an anaerobic bacterium selectively enriched in the faecal and mucosal microbiota from patients with CRC, but its ca
Autor:
Lixia Xu, Jun Yu, Narcissus Teoh, Matthew M. Yeh, Sharon Pok, Geoffrey C. Farrell, Eagle S. H. Chu, Ling Dong, Evi Arfianti, W. Geoffrey Haigh, George N. Ioannou, Xiangchun Li, Joseph J.Y. Sung, Jessie Qiaoyi Liang, Jonathan Chiu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
The underlining mechanisms of dietary cholesterol and nonalcoholic steatohepatitis (NASH) in contributing to hepatocellular carcinoma (HCC) remain undefined. Here we demonstrated that high-fat-non-cholesterol-fed mice developed simple steatosis, whil
Autor:
Wenchao Wei, Feixue Wang, Xiang Zhang, Changan Liu, Jun Yu, Weixin Liu, Chi Chun Wong, Eagle S. H. Chu, Joseph J.Y. Sung
Publikováno v:
Gastroenterology. 160:S-761
Autor:
Jun Yu, Jia Yang, Hong Wei, Yufeng Lin, Chun Ho Szeto, Eagle S. H. Chu, Alvin Ho-Kwan Cheung, Harry C. Lau, Yunfei Zhou, Joseph J.Y. Sung, Huarong Chen
Publikováno v:
Gastroenterology. 160:S-166
Publikováno v:
Gastroenterology. 160:S-732