Pharmacogenomics of hypertension in chronic kidney disease: the CKD-PGX study

Autor: Sher Sj, Eadon Mt, Todd C. Skaar, Arlene B. Chapman, Maddatu J, Miller Bw, Melo Ferreira R, Jing Su, Sinha Ad, Victoria M. Pratt, Sharon M. Moe, Ranjani N. Moorthi

BackgroundPatients with chronic kidney disease (CKD) often have uncontrolled hypertension despite polypharmacy. Pharmacogenomic drug-gene interactions (DGIs) may impact the metabolism or efficacy of antihypertensive agents. We hypothesized that provi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36654d6eb29b450f5f5e6c49539d5b7f
https://doi.org/10.1101/2021.03.30.21254665

Implementation of a pharmacogenomics consult service to support the INGENIOUS trial.

Autor: Eadon, MT, Desta, Z, Levy, KD, Decker, BS, Pierson, RC, Pratt, VM, Callaghan, JT, Rosenman, MB, Carpenter, JS, Holmes, AM, McDonald, CA, Benson, EA, Patil, AS, Vuppalanchi, R, Gufford, BT, Dave, N, Robarge, JD, Hyder, MA, Haas, DM, Kreutz, RP

Publikováno v: Clinical Pharmacology & Therapeutics; Jul2016, Vol. 100 Issue 1, p63-66, 4p

A Precision Mixture Risk Model to Identify Adverse Drug Events in Subpopulations Using a Case-Crossover Design.

Autor: Shi Y; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, USA., Eadon MT; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Chen Y; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, USA., Sun A; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, USA., Yang Y; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, USA., Chiang C; Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA., Donneyong M; College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., Su J; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, USA., Zhang P; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, USA.

Publikováno v: Statistics in medicine [Stat Med] 2024 Nov 30; Vol. 43 (27), pp. 5088-5099. Date of Electronic Publication: 2024 Sep 19.

TrajVis: a visual clinical decision support system to translate artificial intelligence trajectory models in the precision management of chronic kidney disease.

Autor: Li Z; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN 46202, United States.; Department of Computer Graphics Technology, Purdue University, West Lafayette, IN 47907, United States., Liu X; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN 46202, United States., Tang Z; Department of Computer and Information Technology, Purdue University, West Lafayette, IN 47907, United States., Jin N; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN 46202, United States.; Department of Computer and Information Technology, Purdue University, West Lafayette, IN 47907, United States., Zhang P; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN 46202, United States., Eadon MT; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, United States., Song Q; Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL 32610, United States., Chen YV; Department of Computer Graphics Technology, Purdue University, West Lafayette, IN 47907, United States., Su J; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN 46202, United States.; Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27101, United States.

Publikováno v: Journal of the American Medical Informatics Association : JAMIA [J Am Med Inform Assoc] 2024 Nov 01; Vol. 31 (11), pp. 2474-2485.

Development of a Multifaceted Program for Pharmacogenetics Adoption at an Academic Medical Center: Practical Considerations and Lessons Learned.

Autor: Shugg T; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Tillman EM; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Breman AM; Division of Diagnostic Genomics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA., Hodge JC; Division of Diagnostic Genomics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA., McDonald CA; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Ly RC; Division of Diagnostic Genomics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA., Rowe EJ; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Osei W; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Smith TB; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA., Schwartz PH; Division of General Internal Medicine and Geriatrics, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Callaghan JT; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Pratt VM; Division of Diagnostic Genomics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA., Lynch S; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Eadon MT; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Skaar TC; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Publikováno v: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Oct; Vol. 116 (4), pp. 914-931. Date of Electronic Publication: 2024 Aug 21.