Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice

Autor: Akira Yamauchi, Masahiro Yamamura, Keisuke Hino, Kyo Sasaki, Yuichi Hara, Fukuda Kotaro, Sohji Nishina, Kensuke Egashira

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 739-762 (2021)

Background & Aims Immune checkpoint inhibitors have shed light on the importance of antitumor immunity as a therapeutic strategy for hepatocellular carcinoma (HCC). The altered glucose metabolism known as the Warburg effect recently has gained attent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010d385be012e5b858cf3e9cba28a067
https://doi.org/10.1016/j.jcmgh.2020.10.010

Physical and functional interaction of Rnf2 with Af9 regulates basal and aldosterone-stimulated transcription of the α-ENaC gene in a renal collecting duct cell line

Autor: Bruce C. Kone, Zhi Yuan Yu, Qun Kong

Publikováno v: Bioscience Reports

The physical and functional interaction of Rnf2 (RING finger protein 2), a central component of the PRC (Polycomb repressive complex) 1 and Af9 (ALL1-fused gene from chromosome 9 protein), an aldosterone-sensitive transcription factor, in regulating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffff20139c27028bb28215836afd5eb
https://doi.org/10.1042/bsr20130086

The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.

Autor: Young CC; Department of Paediatrics, University of Western Ontario, London, Ontario, Canada; Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada; Department of Oncology, University of Western Ontario, London, Ontario, Canada; Children's Health Research Institute, London, Ontario, Canada., Baker RM; Department of Paediatrics, University of Western Ontario, London, Ontario, Canada; Children's Health Research Institute, London, Ontario, Canada., Howlett CJ; Department of Pathology and Laboratory Medicine, University of Western Ontario, London, Ontario, Canada., Hryciw T; Department of Anatomy and Cell Biology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada; Robarts Research Institute, London, Ontario, Canada., Herman JE; Robarts Research Institute, London, Ontario, Canada., Higgs D; MRC Molecular Haematology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom., Gibbons R; MRC Molecular Haematology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom., Crawford H; Molecular & Integrative Physiology and Internal Medicine, University of Michigan, Ann Arbor, Michigan., Brown A; Department of Anatomy and Cell Biology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada; Robarts Research Institute, London, Ontario, Canada; Children's Health Research Institute, London, Ontario, Canada., Pin CL; Department of Paediatrics, University of Western Ontario, London, Ontario, Canada; Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada; Department of Oncology, University of Western Ontario, London, Ontario, Canada; Children's Health Research Institute, London, Ontario, Canada. Electronic address: cpin@uwo.ca.

Publikováno v: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2018 Sep 14; Vol. 7 (1), pp. 93-113. Date of Electronic Publication: 2018 Sep 14 (Print Publication: 2019).