Zobrazeno 1 - 10
of 31 338
pro vyhledávání: '"EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS"'
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 37-44 (2024)
ABSTRACTVisual impairment associated with uveitis is among the potential complications in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Bioinformatics analyses have shown that some hub genes are closel
Externí odkaz:
https://doaj.org/article/834f0768d7af46efa57c232f77e71c4c
Autor:
Reza Yazdani, Hamed Naziri, Gholamreza Azizi, Bogoljub Ciric, Mozhde Askari, Amir Moghadam Ahmadi, Jaya Aseervatham, Guang-Xian Zhang, Abdolmohamad Rostami
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Interleukin-37 (IL-37) has anti-inflammatory properties in innate and adaptive immunity. Patients with multiple sclerosis (MS), an autoimmune inflammatory demyelinating disease of the central nervous system (CNS), have increased s
Externí odkaz:
https://doaj.org/article/f766f736534e407bbfe611215a4bc599
Autor:
Sienna S. Drake, Aliyah Zaman, Christine Gianfelice, Elizabeth M.-L. Hua, Kali Heale, Elia Afanasiev, Wendy Klement, Jo Anne Stratton, Alexandre Prat, Stephanie Zandee, Alyson E. Fournier
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background The role of senescence in disease contexts is complex, however there is considerable evidence that depletion of senescent cells improves outcomes in a variety of contexts particularly related to aging, cognition, and neurodegenera
Externí odkaz:
https://doaj.org/article/07e09c6af8784c0bbef1de4e6dc3cbe6
Autor:
Li Xin, Adrian Madarasz, Daniela C. Ivan, Florian Weber, Simone Aleandri, Paola Luciani, Giuseppe Locatelli, Steven T. Proulx
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Accumulation of immune cells and proteins in the subarachnoid space (SAS) is found during multiple sclerosis and in the animal model experimental autoimmune encephalomyelitis (EAE). Whether the flow of cerebrospinal fluid (CSF) along the SAS
Externí odkaz:
https://doaj.org/article/96bc5f0b0a0143f2a48746d5826a76eb
Autor:
Gholamreza Azizi, Bram Van den Broek, Larissa Lumi Watanabe Ishikawa, Hamed Naziri, Reza Yazdani, Guang-Xian Zhang, Bogoljub Ciric, Abdolmohamad Rostami
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background The IL-7 receptor alpha (IL-7Rα) binds both IL-7 and thymic stromal lymphopoietin (TSLP). IL-7Rα is essential for the development and survival of naive CD4+ T cells and their differentiation to effector/memory CD4+ T cells. Mice
Externí odkaz:
https://doaj.org/article/846668fffe0b4fe28d72c1b46acd5f96
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract To investigate the spinal cord neuron apoptosis and neuroprotective mechanism of nerve growth factorganismsor (NGF) gene mediated by recombinant adenovirus (Ad-NGF) via peripheral transfection in mice with experimental autoimmune encephalomy
Externí odkaz:
https://doaj.org/article/98c5bf0051e24573bb5f15d4a36ac7f5
Autor:
Su-Min Park, Yong-Hun Oh, Ga-Hyun Lim, Ga-Hee Yun, Kyung-Bo Kim, Ju-Hyun An, Kyung-Won Seo, Hwa-Young Youn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Extracellular vesicles (EVs) from mesenchymal stem cells (MSCs), specifically those preconditioned with deferoxamine (DFO) in canine adipose tissue-derived MSCs (cAT-MSCs), were explored for treating autoimmune diseases. This study assessed
Externí odkaz:
https://doaj.org/article/3a087840206545c69abe070d5d0cd61f
Autor:
Hasan Hüseyin Hendek, Alina Blusch, Neele Heitmann, Sarah Oberhagemann, Seray Demir, Xiomara Pedreiturria, Ralf Gold, Simon Faissner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract So far, only a small number of medications are effective in progressive multiple sclerosis (MS). The sphingosine-1-phosphate-receptor (S1PR)-1,5 modulator siponimod, licensed for progressive MS, is acting both on peripheral immune cells and
Externí odkaz:
https://doaj.org/article/893365440976485ea1a55231324646ed
Autor:
Cuixia Yang, Yuanchen Ma, Qiying Lu, Yuliang Qu, Yuantao Li, Shimei Cheng, Chongjun Xiao, Jinshuo Chen, Chuangjia Wang, Feng Wang, Andy Peng Xiang, Weijun Huang, Xiaorong Tang, Haiqing Zheng
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Treating Multiple sclerosis (MS), a well-known immune-mediated disease characterized by axonal demyelination, is challenging due to its complex causes. Naphthalenedione, present in numerous plants, is being explored as a potential medicine f
Externí odkaz:
https://doaj.org/article/99e7bcf9c25548299887b692c1b76af9
Autor:
Ingrid Berg, Pia Härvelid, Wolfgang Emanuel Zürrer, Marianna Rosso, Daniel S. Reich, Benjamin Victor Ineichen
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105434- (2024)
Summary: Background: Despite successes in multiple sclerosis (MS) drug development, the effectiveness of animal studies in predicting successful bench-to-bedside translation is uncertain. Our goal was to identify predictors of successful animal-to-hu
Externí odkaz:
https://doaj.org/article/8085a892e46248b1945d154f25975289