Zobrazeno 1 - 10
of 503
pro vyhledávání: '"EX VIVO CULTURE"'
Autor:
Daria A. Vorobyeva, Daria M. Potashnikova, Elena V. Maryukhnich, George I. Rusakovich, Anna V. Tvorogova, Anna I. Kalinskaya, Natalia V. Pinegina, Anna V. Kovyrshina, Inna V. Dolzhikova, Alexander B. Postnikov, Fedor N. Rozov, Tatiana N. Sotnikova, Dmitry Yu. Kanner, Denis Yu. Logunov, Alexander L. Gintsburg, Elena J. Vasilieva, Leonid B. Margolis
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe mechanisms of the SARS-CoV-2-triggered complex alterations in immune cell activation and production of cytokines in lung tissue remain poorly understood, in part because of the limited use of adequate tissue models that simulate the s
Externí odkaz:
https://doaj.org/article/672795e7b97040babb51746c3c986fe1
Autor:
Malene Lundgaard Riis, Gaspard Delpouve, John E. Nielsen, Cecilie Melau, Lea Langhoff Thuesen, Kristine Juul Hare, Eva Dreisler, Kasper Aaboe, Pia Tutein Brenøe, Jakob Albrethsen, Hanne Frederiksen, Anders Juul, Paolo Giacobini, Anne Jørgensen
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Sex-specific gonadal differentiation is directed by complex signalling promoting development in either male or female direction, while simultaneously inhibiting the opposite pathway. In mice, the WNT/β-catenin pathway promotes ovarian devel
Externí odkaz:
https://doaj.org/article/9ba84127f86e43e4b357207164f53583
Autor:
Chiang, I-Hsuan a, b, 1, Kuo, Hsuan-Chih b, c, 1, Liao, Chun-Ta b, d, 1, Kuo, Yung-Chia b, c, e, Yu, Shao-Ming b, c, e, Wang, Hung-Ming b, e, Huang, Yi-Hui c, e, Nguyen Thi, Kim Anh b, c, e, Wu, Min-Hsien c, e, f, Hsieh, Jason Chia-Hsun b, c, e, ⁎
Publikováno v:
In Biomedical Journal February 2025 48(1)
Autor:
Malene Lundgaard Riis, Gabriele Matilionyte, John E. Nielsen, Cecilie Melau, David Greenald, Kristine Juul Hare, Lea Langhoff Thuesen, Eva Dreisler, Kasper Aaboe, Pia Tutein Brenøe, Anna-Maria Andersson, Jakob Albrethsen, Hanne Frederiksen, Ewa Rajpert-De Meyts, Anders Juul, Rod T. Mitchell, Anne Jørgensen
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Reduced androgen action during early fetal development has been suggested as the origin of reproductive disorders comprised within the testicular dysgenesis syndrome (TDS). This hypothesis has been supported by studies in rats dem
Externí odkaz:
https://doaj.org/article/6faa0696ef594229b30882d592bea05d
Human precision-cut cystic duct and gallbladder slices: a novel method for studying cholangiopathies
Autor:
Jeske Fridrichs, Bart Hamel, Wendy Kelder, Ewoud van den Hoed, Marius C. van den Heuvel, Jan B. F. Hulscher, Peter Olinga
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Background and aimsPrecision-cut tissue slices (PCTS) are widely used as an ex vivo culture tissue culture technique to study pathogeneses of diseases and drug activities in organs in vitro. A novel application of the PCTS model may be in the field o
Externí odkaz:
https://doaj.org/article/34ad282979d94046bbf1cd2d1f717ab6
Autor:
Cecilie Melau, Berta Gayete Mor, Malene Lundgaard Riis, John E. Nielsen, Eva Dreisler, Kasper Aaboe, Pia Tutein Brenøe, Lea Langhoff Thuesen, Kristine Juul Hare, Rod T. Mitchell, Hanne Frederiksen, Anders Juul, Anne Jørgensen
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionAdministration of dexamethasone (DEX) has been used experimentally to suppress androgenization of external genitalia in 46,XX fetuses with congenital adrenal hyperplasia. Despite this, the prenatal biological mechanism-of-action of DEX on
Externí odkaz:
https://doaj.org/article/9b1a8f93d0f24ffb836d637b277bbce2
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Autor:
Kuen Kuen Lam, Yee Syuen Low, Michelle Lo, Michelle Wong, Choong Leong Tang, Emile Tan, Aik Yong Chok, Isaac Seow-En, Siew Heng Wong, Peh Yean Cheah
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Colorectal cancer (CRC) is the third highest incidence cancer and a leading cause of cancer mortality worldwide. To date, chemotherapeutic treatment of advanced CRC that has metastasized has a dismayed success rate of less than 30%. Further, most (80
Externí odkaz:
https://doaj.org/article/81b1cebe13f34c0d82560ad6fed3b289