Zobrazeno 1 - 10
of 82
pro vyhledávání: '"EV engineering"'
Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Autor:
Shuang Zhao, Yunfeng Di, Huilan Fan, Chengyan Xu, Haijing Li, Yong Wang, Wei Wang, Chun Li, Jingyu Wang
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-23 (2024)
Abstract Extracellular vesicles (EVs) are cell-derived vesicles with a phospholipid bilayer measuring 50–150 nm in diameter with demonstrated therapeutic potentials. Limitations such as the natural biodistribution (mainly concentrated in the liver
Externí odkaz:
https://doaj.org/article/23e394491b984140a858b93cc1c71923
Autor:
Sara Biagiotti, Barbara Canonico, Mattia Tiboni, Faiza Abbas, Elena Perla, Mariele Montanari, Michela Battistelli, Stefano Papa, Luca Casettari, Luigia Rossi, Michele Guescini, Mauro Magnani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Extracellular vesicles (EVs) are promising natural nanocarriers for the delivery of therapeutic agents. As with any other kind of cell, red blood cells (RBCs) produce a limited number of EVs under physiological and pathological conditions. T
Externí odkaz:
https://doaj.org/article/bb826e0143ea47b5a5eb27d8dc5b53fe
Autor:
Rui Chen, Ziqin Kang, Wenhao Li, Tianshu Xu, Yongqiang Wang, Qiming Jiang, Yuepeng Wang, Zixian Huang, Xiaoding Xu, Zhiquan Huang
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) are emerging as promising carriers for the delivery of therapeutic biologics. Genetic engineering represents a robust strategy for loading proteins of interest into EVs. Identification of EV‐enriched proteins f
Externí odkaz:
https://doaj.org/article/eb98012062174fa1bab839e4d2a81060
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 311 (2024)
Small Extracellular Vesicles (sEVs) are typically 30–150 nm in diameter, produced inside cells, and released into the extracellular space. These vesicles carry RNA, DNA, proteins, and lipids that reflect the characteristics of their parent cells, e
Externí odkaz:
https://doaj.org/article/dac4b07891814d1d95e0639dcef65ae8
Akademický článek
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Autor:
Chun-Chieh Huang, Miya Kang, Kasey Leung, Yu Lu, Sajjad Shirazi, Praveen Gajendrareddy, Sriram Ravindran
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Mesenchymal stem cell derived extracellular vesicles (MSC EVs) possess excellent immunomodulatory and therapeutic properties. While beneficial, from a translational perspective, extracellular vesicles with consistent functionality and target specific
Externí odkaz:
https://doaj.org/article/809e56a09b9a4a1684dc5feebd678967
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Osteoarthritis (OA) is a worldwide and disabling disease, which cause severe pain and heavy socioeconomic burden. However, pharmacologic or surgical therapies cannot mitigate OA progression. Mesenchymal stem cells (MSCs) therapy has emerged as potent
Externí odkaz:
https://doaj.org/article/06eb5d410b7944b8998c336350c0bbaa
Akademický článek
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Publikováno v:
Bioengineering, Vol 9, Iss 2, p 56 (2022)
Background: Extracellular vesicles (EVs) are attracting interest as a new class of drug delivery vehicles due to their intrinsic nature of biomolecular transport in the body. We previously demonstrated that EV surface modification with tissue-specifi
Externí odkaz:
https://doaj.org/article/c7d350d7411948b9b4c5a2c5a0e34340
Akademický článek
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