Zobrazeno 1 - 10
of 18
pro vyhledávání: '"ETMR and other Embryonal Tumors"'
Autor:
Irene Slavc, Thomas Czech, Amedeo A. Azizi, Christine Haberler, Lisa Mayr, Andreas Peyrl, Karin Dieckmann, Johannes Gojo
Publikováno v:
Neuro-Oncology
BACKGROUND Embryonal tumor with multilayered rosettes (ETMR) is a rare, aggressive embryonal central nervous system tumor characterized by LIN28A expression and alterations in the C19MC locus. ETMRs predominantly occur in young children, have a disma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ac0f2c4718f6e799306557656c21bf
http://europepmc.org/articles/PMC7715625
http://europepmc.org/articles/PMC7715625
Autor:
G. Yancey Gillespie, Shago Mary, Richard Grundy, Maysa Al-Hussaini, Sarah Leary, Anne Bendel, Mei Lu, Ben Ho, Donna L. Johnston, Eloy Rivas, Nicolas André, Policlinico Vittorio Emanuele, Sandra Camelo-Piragua, Alvaro Lassaletta, Nisreen Amayiri, Nalin Gupta, Jordan R. Hansford, Christine Dahl, Sharon Low, Laura Amariglio, Peter B. Dirks, Palma Solano-Paez, Eric H. Raabe, Tannu Suwal, Mahjouba Boutarbouch, Kuo-Sheng Wu, Luca Massimi, Vicente Santa-Maria, Jesse Kresak, Jean M. Mulcahy Levy, Benjamin Ellezam, Michael D. Taylor, Ramya Ramanujachar, Jorgensen Mette, Somers Gino, Anna Maria Buccoliero, Dariusz Adamek, Cynthia Hawkins, Derek Hanson, Lucie Lafay-Cousin, Andres Morales, David Scharnhorst, Sara Khan, Eric Bouffet, Amy A Smith, Salma Al-Karmi, Maria Joao Gil da Costa, Hwang Eugene, Alyssa Reddy, Sumihito Nobusawa, Holly Lindsey, Jean Michaud, Andrew W. Walter, Lili-Naz Hazrati, Daniel Catchpoole, Tai-Tong Wong, Amar Gajjar, Yin Wang, Ashley Plant, Rubens Jeffery, Ahmet Muzaffer Demir, Hideo Nakamura, Derek Stephens, Andrew Dodgshun, Maryam Fouladi, Paul Wood, Christopher L. Moertel, Enrica Tan, Nicholas Gerber, David S. Ziegler, Nicholas G. Gottardo, Jason Fangusaro, Milena La Spina, Christelle Dufour, Annie Huang, Young-Shin Ra, Tarik Tihan, Nabil Kabbara, Franck Bourdeaut, Michal Yalon-Oren, Ute Bartels, Christopher Dunham
Publikováno v:
Neuro-Oncology
ETMR, an aggressive disease characterised by C19MC alterations, were previously categorised as various histologic diagnoses. The clinical spectrum and impact of conventional multi-modal therapy on this new WHO diagnostic category remains poorly under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc130fbfb4dcec76baeeae0e3978fd1
http://europepmc.org/articles/PMC7715263
http://europepmc.org/articles/PMC7715263
Autor:
Nicolas U. Gerber, Monika Warmuth-Metz, Björn-Ole Juhnke, M Kool, Stefan Rutkowski, Ulrich Schüller, Christine Haberler, Brigitte Bison, Stefan M. Pfister, Torsten Pietsch, Katja von Hoff, Carsten Friedrich, Rolf-Dieter Kortmann, Martin Mynarek, Marco Gessi
Publikováno v:
Neuro-Oncology
BACKGROUND Embryonal tumours with multilayered rosettes (ETMR) are highly aggressive tumors, mostly occurring in infants. Published clinical data refer to retrospective cohorts of inhomogeneously treated patients. Here, we describe the outcome of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6751a13789739f4f58a56a8a6d830e2f
https://doi.org/10.1093/neuonc/noaa222.218
https://doi.org/10.1093/neuonc/noaa222.218
Publikováno v:
Neuro-Oncology
Embryonal tumors with multilayered rosettes (ETMRs) are highly fatal diseases characterized by recurrent amplification of C19MC, an oncogenic miRNA cluster. While C19MC was discovered as a major driver of ETMRs, its direct role in ETMRs remains unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd5408031d51190034f49555c4eacce
http://europepmc.org/articles/PMC7715313
http://europepmc.org/articles/PMC7715313
Publikováno v:
Neuro-Oncology
INTRODUCTION Central nervous system (CNS) embryonal tumor is a group of rare, poorly differentiated neuroepithelial malignant neoplasm predominantly occurs in pediatrics. Herein, we firstly report a CNS embryonal tumor harboring pathogenic CIC-LEUTX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222149f7fe80b0da72538a2dd3eeffc7
http://europepmc.org/articles/PMC7715287
http://europepmc.org/articles/PMC7715287
Autor:
David W. Ellison, Daniel C. Bowers, Paul A. Northcott, Paul Klimo, Giles W. Robinson, Jason Chiang, Thomas E. Merchant, Laure Bihannic, David T.W. Jones, Leena Paul, Anthony P. Y. Liu, Michael Fisher, Sridharan Gururangan, Eric Bouffet, David Meredith, Rahul Kumar, John R. Crawford, Murali Chintagumpala, Tim Hassall, Amar Gajjar, Bernhard Englinger, Sanda Alexandrescu, Tong Lin, Frederick A. Boop, Daniel J. Indelicato, Yiai Tong, Mariella G. Filbin, Stewart J. Kellie, Brent A. Orr, Elke Pfaff, Brian Gudenas
Publikováno v:
Neuro-Oncology
Pineoblastoma (PB) is an aggressive embryonal brain tumor comprising 1% of pediatric CNS tumors. The clinico-molecular heterogeneity and developmental origins underlying PB are poorly understood; therefore, we have assembled a molecular cohort of his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1162b1547a305a88724b471ca1b859
http://europepmc.org/articles/PMC7715543
http://europepmc.org/articles/PMC7715543
Autor:
Takako Yoshioka, Meri Uchiyama, Masayuki Nakano, Masahiro Sugawa, Yoshiaki Tsutsumi, Kenichi Usami, Hideki Ogiwara, Kenichi Sakamoto, Kimikazu Matsumoto, Motohiro Kato, Keita Terashima, Takanori Mizuno, Yukihiro Matsukawa, Kyohei Isshiki, Tomoo Osumi, Yoshihiro Gocho, Daisuke Tomizawa, Shinichi Tsujimoto, Chikako Kiyotani, Yoko Shioda
Publikováno v:
Neuro-Oncology
BACKGROUND Primary diffuse leptomeningeal primitive neuroectodermal tumor (PDL PNET) is a rare embryonal brain tumor which arises primarily in the meninges without an intraparenchymal mass. Few previous reports of this condition exist, and the clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31dd52147bec5a0f1d0600121d77566c
https://doi.org/10.1093/neuonc/noaa222.215
https://doi.org/10.1093/neuonc/noaa222.215
Autor:
Marta Interlandi, Viktoria Melcher, Flavia W de Faria, Monika Graf, Thomas K Albert, Kornelius Kerl, Natalia Moreno
Publikováno v:
Neuro-Oncology
Embryonal tumors with multilayered rosettes (ETMR) are deadly brain malignancies affecting young children. No standard treatment is available and the median survival is less than 12 months. Molecularly, the disease is characterized by the miRNA C19MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12cf03930b6862c20bb052759d23c89
http://europepmc.org/articles/PMC7715162
http://europepmc.org/articles/PMC7715162
Autor:
Heather Meador, Sheetal Phadnis, Leena Ketonen, Nelda Itzep, Bhanu Gogia, Wafik Zaky, Citla Sridhar, David I. Sandberg, Soumen Khatua, Greg Fuller
Publikováno v:
Neuro-Oncology
BACKGROUND Embryonal Tumor with Multilayered Rosettes (ETMR) are rare tumors that are molecularly diagnosed by C19MC amplification. Rarity of this tumor has precluded profiling uniform therapeutic strategy. METHODS Retrospective review after institut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29dd2f9ed6cd350fa30120ad793cb5b9
https://doi.org/10.1093/neuonc/noaa222.208
https://doi.org/10.1093/neuonc/noaa222.208
Autor:
Anna Avagyan, Julieta Hoveyan, Samvel Bardakhchyan, Ruzanna Papyan, Samvel Iskanyan, Garik Hovhannisyan, Manushak Avagyan, Parandzem Khachatryan, Gevorg Tamamyan, Samvel Danielyan
Publikováno v:
Neuro-Oncology
INTRODUCTION Embryonal tumor with abundant neuropil and true rosettes (ETANTR) is a rare aggressive brain tumor with low survival rates. There are about 80 cases reported in literature since 2000 when it was first described. There is no standard trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a416214ce001bd494bc49c8f20c91613
http://europepmc.org/articles/PMC7715241
http://europepmc.org/articles/PMC7715241