Zobrazeno 1 - 10
of 18
pro vyhledávání: '"ET, endothelin"'
Autor:
Marlowe W. Eldridge, Farhan Raza, James R. Runo, Theodore J. Berei, Naomi C. Chesler, Callyn Kozitza, Amy Chybowski, Kara N. Goss
Publikováno v:
JACC Case Reports
A 48-year-old woman who had been receiving long-term interferon-β for 8 years for multiple sclerosis developed drug-induced World Health Organization group I pulmonary arterial hypertension. Triple therapy for pulmonary arterial hypertension and sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c5a1badd5bbaaffc9933e777265a3d
http://europepmc.org/articles/PMC8311374
http://europepmc.org/articles/PMC8311374
Autor:
Christophe Casteleyn, Benedicte Y. De Winter, Sven Francque, Luisa Vonghia, Denise van der Graaff, Isabel Pintelon, Joris G. De Man, Jean-Pierre Timmermans, Wilhelmus J. Kwanten, Shivani Chotkoe
Publikováno v:
JHEP Reports
JHEP Reports, Vol 4, Iss 2, Pp 100412-(2022)
JHEP Reports, Vol 4, Iss 2, Pp 100412-(2022)
Background & Aims Intrahepatic vascular resistance is increased in early non-alcoholic fatty liver disease (NAFLD), potentially leading to tissue hypoxia and triggering disease progression. Hepatic vascular hyperreactivity to vasoconstrictors has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d7ccc5a41f528c2d7c72daa5110765
http://europepmc.org/articles/PMC8749167
http://europepmc.org/articles/PMC8749167
Publikováno v:
Journal of Advanced Research
Graphical abstract
Introduction Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury.
Introduction Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9de6be7acea23fd93887832ef07452a1
https://pubmed.ncbi.nlm.nih.gov/35024180
https://pubmed.ncbi.nlm.nih.gov/35024180
Autor:
Adam P. Hill, Calum A. MacRae, Diane Fatkin, Michael P. Feneley, Ze-Yan Yu, Boris Martinac, Jasmina Cvetkovska, Charles D. Cox, Victoria Benson, Andreas A. Werdich, Inken G. Huttner, Vesna Nikolova-Krstevski, Soeren Wagner, Oliver Friedrich
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 5, Pp 575-590 (2017)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • TRPC-6 is present in atrial endocardial endothelium in humans, pigs, and mice. • Endocardial TRPC-6 channels act as atrial mechanosensors, showing changes in localization, expression levels, and activity in respo
Highlights • TRPC-6 is present in atrial endocardial endothelium in humans, pigs, and mice. • Endocardial TRPC-6 channels act as atrial mechanosensors, showing changes in localization, expression levels, and activity in respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2793e89894cde49914a95e7466806369
https://doi.org/10.1016/j.jacbts.2017.05.006
https://doi.org/10.1016/j.jacbts.2017.05.006
Publikováno v:
Paediatrics Publications
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 861-870 (2018)
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 861-870 (2018)
JACC: Basic to Translational Science
Summary The clinical use of doxorubicin in cancer is limited by cardiotoxic effects that can lead to heart failure. Whereas earlier work focused on the direct impact of doxorubicin on cardiomyocytes, recent studies have turned to the endothelium, bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabc9d341267a231c574509af74d895f
https://ir.lib.uwo.ca/paedpub/2480
https://ir.lib.uwo.ca/paedpub/2480
Autor:
Lian-Di Kan, Liu-Cheng Li
Publikováno v:
Journal of Ethnopharmacology
Ethnopharmacological relevance Pulmonary fibrosis (PF) is a chronic, debilitating and often lethal lung disorder. Despite the molecular mechanisms of PF are gradually clear with numerous researchers’ efforts, few effective drugs have been developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f97bf29106c253c558febd6a4a85a0
https://pubmed.ncbi.nlm.nih.gov/28038955
https://pubmed.ncbi.nlm.nih.gov/28038955
Autor:
Isabel, Heidegger, Petra, Massoner, Iris E, Eder, Andreas, Pircher, Renate, Pichler, Friedrich, Aigner, Jasmin, Bektic, Wolfgang, Horninger, Helmut, Klocker
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology
Highlights • New drugs approved for treatment of castration resistant prostate cancer. • Prime targets: androgen receptor, bone cells, cell division, immune system. • Several promising drugs disappointed in clinical trials. • Further efforts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d74f1221bcd0c81e0fa7c369222825c6
https://pubmed.ncbi.nlm.nih.gov/23792785
https://pubmed.ncbi.nlm.nih.gov/23792785
Publikováno v:
Biochemical Journal
Wnt signalling pathways have been shown to play key roles in both normal development and tumorigenesis. Progression of many human cancers is associated with defined mutations in Wnt pathway components that result in dysregulated β-catenin-mediated g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78227cf9ee2595792ebf0003fba19151
https://pubmed.ncbi.nlm.nih.gov/21668411
https://pubmed.ncbi.nlm.nih.gov/21668411
Publikováno v:
ASN Neuro, Vol 1 (2009)
ASN NEURO
ASN NEURO
Microvascular dysfunction, loss of vascular support, ischaemia and sub-acute vascular instability in surviving blood vessels contribute to secondary injury following SCI (spinal cord injury). Neither the precise temporal profile of the cellular dynam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204a37169ff82d6095c8f0947780011f
https://doaj.org/article/b42cfd3ec5b94a3ca8a44722306a48aa
https://doaj.org/article/b42cfd3ec5b94a3ca8a44722306a48aa
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