Zobrazeno 1 - 10
of 26
pro vyhledávání: '"ESRA AYAN"'
Autor:
Mehmet Gul, Esra Ayan, Ebru Destan, J. Austin Johnson, Alaleh Shafiei, Abdullah Kepceoğlu, Merve Yilmaz, Fatma Betül Ertem, İlkin Yapici, Bilge Tosun, Nilüfer Baldir, Nurettin Tokay, Zeliş Nergiz, Gözde Karakadioğlu, Seyide Seda Paydos, Cahine Kulakman, Cengiz Kaan Ferah, Ömür Güven, Necati Atalay, Enver Kamil Akcan, Haluk Cetinok, Nazlı Eylül Arslan, Kardelen Şabanoğlu, Bengisu Aşci, Serra Tavli, Helin Gümüsboğa, Sevde Altuntaş, Masami Otsuka, Mikako Fujita, Şaban Teki̇n, Halilibrahim Çi̇ftçi̇, Serdar Durdaği, Ezgi Karaca, Burcu Kaplan Türköz, Burak Veli Kabasakal, Ahmet Kati, Hasan DeMi̇rci̇
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract High-resolution biomacromolecular structure determination is essential to better understand protein function and dynamics. Serial crystallography is an emerging structural biology technique which has fundamental limitations due to either sam
Externí odkaz:
https://doaj.org/article/f18f8cb3aa204e4c80e833bbd23b31ce
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12819 (2023)
Alzheimer’s Disease (AD) is a progressively debilitating form of dementia that affects millions of individuals worldwide. Although a vast amount of research has investigated the complex interplay between gut microbiota and neurodegeneration, the me
Externí odkaz:
https://doaj.org/article/a0976e05f06f42618f1980204eb90aa0
Autor:
Esra Ayan, Busra Yuksel, Ebru Destan, Fatma Betul Ertem, Gunseli Yildirim, Meryem Eren, Oleksandr M. Yefanov, Anton Barty, Alexandra Tolstikova, Gihan K. Ketawala, Sabine Botha, E. Han Dao, Brandon Hayes, Mengning Liang, Matthew H. Seaberg, Mark S. Hunter, Alexander Batyuk, Valerio Mariani, Zhen Su, Frederic Poitevin, Chun Hong Yoon, Christopher Kupitz, Aina Cohen, Tzanko Doukov, Raymond G. Sierra, Çağdaş Dağ, Hasan DeMirci
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Ayan et al. report two structures of the protein streptavidin - one at ambient temperature determined using serial femtosecond crystallography and a second one determined at cryogenic temperature. These results provide insights into the structural dy
Externí odkaz:
https://doaj.org/article/ce08830956e641dd939e81eeed58b63b
Autor:
Ebru Destan, Busra Yuksel, Bradley B. Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A. Francis, Hasan DeMirci
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The ammonia-oxidizing thaumarchaeal 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle is one of the most energy-efficient CO2 fixation cycles discovered thus far. The protein encoded by Nmar_1308 (from Nitrosopumilus maritimus SCM1) is a
Externí odkaz:
https://doaj.org/article/9facd89c002a40c5b7cd6090b588717b
Autor:
Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Kensaku Anraku, Kazuaki Monde, Çağdaş Dağ, Ebru Destan, Busra Yuksel, Esra Ayan, Gunseli Yildirim, Merve Yigin, F. Betul Ertem, Alaleh Shafiei, Omur Guven, Sabri O. Besler, Raymond G. Sierra, Chun Hong Yoon, Zhen Su, Mengling Liang, Burcin Acar, Turkan Haliloglu, Masami Otsuka, Fumiaki Yumoto, Mikako Fujita, Toshiya Senda, Hasan DeMirci
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Oligomerization of Pr55Gag is a critical step of the late stage of the HIV life cycle. It has been known that the binding of IP6, an abundant endogenous cyclitol molecule at the MA domain, has been linked to the oligomerization of Pr55Gag. H
Externí odkaz:
https://doaj.org/article/77d919cd60ce407e9fad3b1b4378ff45
Publikováno v:
Crystals, Vol 13, Iss 4, p 648 (2023)
The treatment of insulin-dependent diabetes mellitus is characterized by artificial supplementation of pancreatic β-cell ability to regulate sugar levels in the blood. Even though various insulin analogs are crucial for reasonable glycemic control,
Externí odkaz:
https://doaj.org/article/80d0008fd1f84656b3891242706117b5
Autor:
Fatma Betul Ertem, Omur Guven, Cengizhan Buyukdag, Oktay Gocenler, Esra Ayan, Busra Yuksel, Mehmet Gul, Gozde Usta, Barıs Cakılkaya, J. Austin Johnson, E. Han Dao, Zhen Su, Frederic Poitevin, Chun Hong Yoon, Christopher Kupitz, Brandon Hayes, Mengning Liang, Mark S. Hunter, Alexander Batyuk, Raymond G. Sierra, Gihan Ketawala, Sabine Botha, Çağdaş Dağ, Hasan DeMirci
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101158- (2022)
Summary: The SARS-CoV-2 main protease of (Mpro) is an important target for SARS-CoV-2 related drug repurposing and development studies. Here, we describe the steps for structural characterization of SARS-CoV-2 Mpro, starting from plasmid preparation
Externí odkaz:
https://doaj.org/article/57d9c8025fa44a7b88ba24db6f0d7586
Autor:
Halilibrahim Ciftci, Belgin Sever, Esra Ayan, Mustafa Can, Hasan DeMirci, Masami Otsuka, Amaç Fatih TuYuN, Hiroshi Tateishi, Mikako Fujita
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1255 (2022)
The HIV-1 Gag protein binds to the host cell membrane and assembles into immature particles. Then, in the course of immature virion budding, activated protease cleaves Gag into its main components: MA, CA, NC, and p6 proteins. The highly basic residu
Externí odkaz:
https://doaj.org/article/c028dc50876040c582b307116b9e1d7c
Autor:
Omur Guven, Mehmet Gul, Esra Ayan, J Austin Johnson, Baris Cakilkaya, Gozde Usta, Fatma Betul Ertem, Nurettin Tokay, Busra Yuksel, Oktay Gocenler, Cengizhan Buyukdag, Sabine Botha, Gihan Ketawala, Zhen Su, Brandon Hayes, Frederic Poitevin, Alexander Batyuk, Chun Hong Yoon, Christopher Kupitz, Serdar Durdagi, Raymond G. Sierra, Hasan DeMirci
Publikováno v:
Crystals, Vol 11, Iss 12, p 1579 (2021)
Since early 2020, COVID-19 has grown to affect the lives of billions globally. A worldwide investigation has been ongoing for characterizing the virus and also for finding an effective drug and developing vaccines. As time has been of the essence, a
Externí odkaz:
https://doaj.org/article/304b6058372a49cd8edb08044f9a1e25
Autor:
NECATİ ATALAY, ENVER KAMİL AKCAN, MEHMET GÜL, ESRA AYAN, EBRU DESTAN, FATMA BETÜL ERTEM KUZUCU, NURETTİN TOKAY, BARIŞ ÇAKILKAYA, ZELİŞ NERGİZ, GÖZDE KARAKADIOĞLU USTA, ABDULLAH KEPCEOĞLU, İLKİN YAPICI, BİLGE TOSUN, NİLÜFER BALDIR, GÜNSELİ YILDIRIM, J AUSTIN JOHNSON, ÖMÜR GÜVEN, ALALEH SHAFIEI, NAZLI EYLÜL ARSLAN, MERVE YILMAZ, CAHİNE KULAKMAN, SEYİDE SEDA PAYDOS, SEYNEP SENA ÇİNAL, KARDELEN ŞABANOĞLU, AYŞEGÜL PAZARÇEVİREN, AYŞENUR YILMAZ, BAŞAK CANBAY, BENGİSU AŞÇI, ESRA KARTAL, SERRA TAVLI, MEHMET ÇALISEKİ, GÜNCE GÖÇ, ARİF MERMER, GAMZE YEŞİLAY, SEVDE ALTUNTAŞ, HIROSHI TATEISHI, MASAMI OTSUKA, MIKAKO FUJITA, ŞABAN TEKİN, HALİLİBRAHİM ÇİFTÇİ, SERDAR DURDAĞI, GİZEM DİNLER DOĞANAY, EZGİ KARACA, BURCU KAPLAN TÜRKÖZ, BURAK VELİ KABASAKAL, AHMET KATI, HASAN DEMİRCİ
Publikováno v:
Turkish Journal of Biology. 47:1-13