Summer Lecture 2002 (Bio-Science) of Osaka kyoiku University Cooperation with High Schools [Should We Make Clones of Human Beings-Copies, Perhaps, of a Beautiful Mother, from ES (Embryonic Stem) Cells?]

Publikováno v: 大阪教育大学紀要. V, 教科教育. 53(1):45-58

大阪教育大学と大阪府立の清水谷高校及び夕陽丘高校との高大連携夏期講座において『ES細胞からクローン人間へ, そのクローン無性生殖の結果は?』という題目のもと約40名の高校生に, 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::3f23f886e32cbb89e2f6a2cf23ec4362
http://ir.lib.osaka-kyoiku.ac.jp/dspace/handle/123456789/172

Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains

Autor: Zhen Li, Xianbin Tian, Lilian Kisiswa, Ajeena Ramanujan, Ning Zhang, Carlos F. Ibáñez, Wensu Yuan, Zhi Lin, Eunice Weiling Sim

Publikováno v: Zhang, N, Kisiswa, L, Ramanujan, A, Li, Z, Sim, E W, Tian, X, Yuan, W, Ibáñez, C F & Lin, Z 2021, ' Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains ', Journal of Biological Chemistry, vol. 297, no. 2, 100916 . https://doi.org/10.1016/j.jbc.2021.100916
The Journal of Biological Chemistry

The p75 neurotrophin receptor (p75NTR) is a critical mediator of neuronal death and tissue remodeling and has been implicated in various neurodegenerative diseases and cancers. The death domain (DD) of p75NTR is an intracellular signaling hub and has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0bbd2cb844bf0783353c7d641f4ec8
https://pure.au.dk/portal/da/publications/structural-basis-of-nfb-signaling-by-the-p75-neurotrophin-receptor-interaction-with-adaptor-protein-tradd-through-their-respective-death-domains(955eafca-a0a5-442c-8b0e-8eceffee7ca1).html

A common human missense mutation of vesicle coat protein SEC23B leads to growth restriction and chronic pancreatitis in mice

Autor: Wei Wei, Zhigang Liu, Chao Zhang, Rami Khoriaty, Min Zhu, Bin Zhang

Publikováno v: The Journal of Biological Chemistry

SEC23B is one of two vertebrate paralogs of SEC23, a key component of the coat protein complex II vesicles. Complete deficiency of SEC23B in mice leads to perinatal death caused by massive degeneration of professional secretory tissues. However, func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e451add9825cedad54eb1e03a007f1a
https://doi.org/10.1016/j.jbc.2021.101536

The transcription factor BACH1 at the crossroads of cancer biology: From epithelial–mesenchymal transition to ferroptosis

Autor: Mitsuyo Matsumoto, Hironari Nishizawa, Yuriko Saiki, Kazuhiko Igarashi

Publikováno v: The Journal of Biological Chemistry

The progression of cancer involves not only the gradual evolution of cells by mutations in DNA but also alterations in the gene expression induced by those mutations and input from the surrounding microenvironment. Such alterations contribute to canc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93ddeab3e30d4b92868b229475d7a4b
https://doi.org/10.1016/j.jbc.2021.101032

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+–Cl− co-transporters

Autor: David G. Campbell, Paola de los Heros, Thomas Macartney, Dario R. Alessi, Maria Deak, Jinwei Zhang, Kristopher T. Kahle, Robert Gourlay

Publikováno v: Biochemical Journal

Precise homoeostasis of the intracellular concentration of Cl− is achieved via the co-ordinated activities of the Cl− influx and efflux. We demonstrate that the WNK (WNK lysine-deficient protein kinase)-activated SPAK (SPS1-related proline/alanin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9063ba5b305ec116dd7bca053da41fc
https://doi.org/10.1042/bj20131478