Zobrazeno 1 - 10
of 57
pro vyhledávání: '"ERN1 knockdown"'
Publikováno v:
Biotechnologia Acta, Vol 17, Iss 2, Pp 67-69 (2024)
Aim. The purpose of the study was to investigate the impact of graphene oxide nanoparticles on the expression of a subset of ER stress-dependent genes in normal human astrocytes in comparison with glioblastoma cells depending on the knockdown of ERN1
Externí odkaz:
https://doaj.org/article/b3c78d8f2f0141b993551f8552ce8b4c
Autor:
Minchenko Oleksandr H., Abramchuk Anastasiia I., Khita Olena O., Sliusar Myroslava Y., Viletska Yuliia M., Minchenko Dmytro O.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 206-214 (2024)
Objective. Carboxypeptidase E (CPE) plays an important role in the biosynthesis of neurotransmitters and peptide hormones including insulin. It also promotes cell proliferation, survival, and invasion of tumor cells. The endoplasmic reticulum stress,
Externí odkaz:
https://doaj.org/article/3009a13843a6451d8b39bd696d3a6145
Autor:
Minchenko Oleksandr H., Sliusar Myroslava Y., Khita Olena O., Viletska Yuliia M., Luzina Olha Y., Danilovskyi Serhiy V., Minchenko Dmytro O.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 144-152 (2024)
Objective. Serine hydroxymethyltransferase (SHMT2) plays a multifunctional role in mitochondria (folate-dependent tRNA methylation, translation, and thymidylate synthesis). The endoplasmic reticulum stress, hypoxia, and glucose and glutamine supply a
Externí odkaz:
https://doaj.org/article/8492f2f39bcd4c8f97216ef7a540237f
Autor:
Minchenko Oleksandr H., Sliusar Myroslava Y., Khita Olena O., Minchenko Dmytro O., Viletska Yuliia M., Halkin Oleh V., Levadna Liudmyla O., Cherednychenko Anastasiia A., Khikhlo Yevgen P.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 91-100 (2024)
Objective. Glucose and glutamine supply as well as serine synthesis and endoplasmic reticulum (ER) stress are important factors of glioblastoma growth. Previous studies showed that the knockdown of ERN1 (ER to nucleus signaling 1) suppressed glioblas
Externí odkaz:
https://doaj.org/article/fe2223a129ea40ada897520c36364990
Autor:
Krasnytska Daria A., Khita Olena O., Viletska Yuliia M., Minchenko Dmytro O., Halkin Oleh V., Rudnytska Olha V., Hoian Sofiia L., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 47-56 (2024)
Homeobox genes play an important role in health and disease including oncogenesis. The present investigation aimed to study ERN1-dependent hypoxic regulation of the expression of genes encoding homeobox proteins MEIS (zinc finger E-box binding homeob
Externí odkaz:
https://doaj.org/article/f7aa9d84f6224def9fd6df5e506bf5f0
Autor:
Minchenko Oleksandr, Kulish Yuliia V., Viletska Yuliia M., Khita Olena O., Rudnytska Olha V., Kozynkevych Halyna E., Minchenko Dmytro O.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1 (2024)
Objective. Nanographene oxide (nGO) nanoparticles (NPs) have unique properties and are widely used in various fields, including biomedicine. These NPs, however, also exhibit toxic effects and therefore, the understanding of the molecular mechanism
Externí odkaz:
https://doaj.org/article/6299f828db9e43e8b2edc77ee876dee1
Autor:
Sliusar Myroslava Y., Minchenko Dmytro O., Khita Olena O., Tsymbal Dariia O., Viletska Yuliia M., Luzina Olha Y., Danilovskyi Serhij V., Ratushna Oksana O., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 57, Iss 1, Pp 252-261 (2023)
Objective. Serine synthesis as well as endoplasmic reticulum stress and hypoxia are important factors of malignant tumor growth including glioblastoma. Previous studies have shown that the knockdown of ERN1 (endoplasmic reticulum to nucleus signaling
Externí odkaz:
https://doaj.org/article/4aefa70ee11343659d21bbc7b8f50335
Autor:
Krasnytska Dariia O., Viletska Yuliia M., Minchenko Dmytro O., Khita Olena O., Tsymbal Dariia O., Cherednychenko Anastasiia A., Kozynkevych Halyna E., Oksiom Nataliia S., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 57, Iss 1, Pp 37-47 (2023)
Objective. Homeobox genes play a fundamental role in the embryogenesis, but some of them have been linked to oncogenesis. The present study is aimed to investigate the impact of glucose and glutamine deprivations on the expression of homeobox genes s
Externí odkaz:
https://doaj.org/article/8785ec42d410459e90ae227b34b9bbf3
Autor:
Shatokhina Hanna O., Khita Olena O., Minchenko Dmytro O., Tsymbal Dariia O., Luzina Olha R., Danilovskyi Serhiy V., Sliusar Myroslava Y., Levadna Liudmyla O., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 56, Iss 4, Pp 254-264 (2022)
Objective. The aim of the present study was to investigate the expression of pyruvate dehydrogenase genes such as PDHA1, PDHB, DLAT, DLD, and PDHX in U87 glioma cells in response to glutamine and glucose deprivations in control glioma cells and endop
Externí odkaz:
https://doaj.org/article/6cf314c9701640bba86af4adc822845c
Autor:
Krasnytska Dariia A., Khita Olena O., Tsymbal Dariia O., Luzina Olha Y., Cherednychenko Anastasiia A., Kozynkevich Halyna E., Bezrodny Borys H., Minchenko Dmytro O.
Publikováno v:
Endocrine Regulations, Vol 56, Iss 1, Pp 38-47 (2022)
Objective. The aim of the current study was to investigate the expression of genes encoded homeobox proteins such as MEIS3 (Meis homeobox 3), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1), LHX2, and LHX6 in U87 glioma cells in response to
Externí odkaz:
https://doaj.org/article/379010e6461c428e80925df11121b8bf