Zobrazeno 1 - 8
of 8
pro vyhledávání: '"ERMS, Embryonal Rhabdomyosarcoma"'
Autor:
Ufuk Erdogdu, Nadezda Dolgikh, Stephanie Laszig, Vinzenz Särchen, Michael T. Meister, Marek Wanior, Stefan Knapp, Cathinka Boedicker
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 109-119 (2022)
Neoplasia (New York, N.Y.)
Neoplasia
Neoplasia (New York, N.Y.)
Neoplasia
Highlights • Co-inhibition of BET proteins and anti-apoptotic BCL-2 proteins induces apoptosis in RMS. • JQ1 and BH3-mimetics synergistically induce cell death in RMS. • Cell death is caspase-dependent and displays hallmarks of intrinsic apopto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbac6aac81f4d40d574992bf92415f7
https://doi.org/10.1016/j.neo.2021.11.012
https://doi.org/10.1016/j.neo.2021.11.012
Autor:
Sheetal A. Mitra, Yong-Hwee Eddie Loh, Zesheng Wan, Xiaogang Hou, Katherine K. Slemmons, Emad Darvishi, Lee J. Helman, Jean Hugues Parmentier
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 7, Pp 274-282 (2020)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 7, Pp 274-282 (2020)
Fibroblast growth factor receptor 4 (FGFR4) aberrant expression and activity have been linked to the pathogenesis of a variety of cancers including rhabdomyosarcomas (RMS). We found that treatment of alveolar rhabdomyosarcoma (aRMS) cells with Guadec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbb00a4835ceb41f1ff2fb3518bbe12
https://pubmed.ncbi.nlm.nih.gov/32464274
https://pubmed.ncbi.nlm.nih.gov/32464274
Autor:
Elisabetta Rossi, Angelica Zin, Paolo Bonvini, Gianni Bisogno, Rita Zamarchi, Luisa Santoro, Lucia Tombolan
Publikováno v:
Translational Oncology, Vol 13, Iss 11, Pp 100846-(2020)
Transl Oncol
Translational Oncology
Transl Oncol
Translational Oncology
EpCAM is a transmembrane glycoprotein typically overexpressed in cancer of epithelial origin and mainly involved in the epithelial-to–mesenchymal transition (EMT) of tumor cells that spread and disseminate. Strategies for the targeting and capture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccdf572769071249209e2445c2e5d204
http://hdl.handle.net/11577/3353828
http://hdl.handle.net/11577/3353828
Publikováno v:
Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biology
Redox Biology
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma accounting for 5–8% of malignant tumours in children and adolescents. Children with high risk disease have poor prognosis. Anti-RMS therapies include surgery, radiation and combination c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c9157b323344d511e141abe0023e4d
http://www.sciencedirect.com/science/article/pii/S2213231718311406
http://www.sciencedirect.com/science/article/pii/S2213231718311406
Akademický článek
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Autor:
Michelle Haber, Glenn M. Marshall, Jennifer A. Byrne, David S. Ziegler, Murray D. Norris, Federica Saletta, Geoffrey McCowage, Carol Wadham
Publikováno v:
BBA Clinical
Background Technological advances including high-throughput sequencing have identified numerous tumor-specific genetic changes in pediatric and adolescent cancers that can be exploited as targets for novel therapies. Scope of review This review provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d23899601b6c04d286e686871c94b25
Autor:
Svoboda LK; a Translational Oncology Program and the Departments of Pediatric and Communicable Diseases; University of Michigan ; Ann Arbor , MI USA., Harris A, Bailey NJ, Schwentner R, Tomazou E, von Levetzow C, Magnuson B, Ljungman M, Kovar H, Lawlor ER
Publikováno v:
Epigenetics [Epigenetics] 2014 Dec; Vol. 9 (12), pp. 1613-25.
Autor:
Saletta F; Children's Cancer Research Unit, Kids Research Institute, Westmead 2145, New South Wales, Australia., Wadham C; Children's Cancer Institute Australia, Lowy Cancer Research Centre, UNSW, Randwick 2031, New South Wales, Australia., Ziegler DS; Children's Cancer Institute Australia, Lowy Cancer Research Centre, UNSW, Randwick 2031, New South Wales, Australia ; Kids Cancer Centre, Sydney Children's Hospital, Randwick 2031, New South Wales, Australia., Marshall GM; Children's Cancer Institute Australia, Lowy Cancer Research Centre, UNSW, Randwick 2031, New South Wales, Australia ; Kids Cancer Centre, Sydney Children's Hospital, Randwick 2031, New South Wales, Australia., Haber M; Children's Cancer Institute Australia, Lowy Cancer Research Centre, UNSW, Randwick 2031, New South Wales, Australia., McCowage G; The Children's Hospital at Westmead, Westmead 2145, New South Wales, Australia., Norris MD; Children's Cancer Institute Australia, Lowy Cancer Research Centre, UNSW, Randwick 2031, New South Wales, Australia., Byrne JA; Children's Cancer Research Unit, Kids Research Institute, Westmead 2145, New South Wales, Australia ; The University of Sydney Discipline of Paediatrics and Child Health, The Children's Hospital at Westmead, Westmead 2145, New South Wales, Australia.
Publikováno v:
BBA clinical [BBA Clin] 2014 Jun 28; Vol. 1, pp. 59-77. Date of Electronic Publication: 2014 Jun 28 (Print Publication: 2014).