Zobrazeno 1 - 10
of 283
pro vyhledávání: '"ERK1/2 pathway"'
Autor:
Xiao Bingkai, Zhang Yue, Lu Zekun, Chen Weibo, An Yong, Zu Guangchen, Xu Xiaowu, Wu Di, Yang Hao, Qin Yi, Chen Xuemin
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 54, Pp 1431-1440 (2022)
ERK1/2 are essential proteins mediating mitogen-activated protein kinase signaling downstream of RAS in pancreatic adenocarcinoma (PDAC). Our previous study reveals that ARF6 plays a positive regulatory role in ERK1/2 pathway in a feedback loop manne
Externí odkaz:
https://doaj.org/article/d11982babacd4abfb631a6e9b866013e
Akademický článek
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Autor:
Mei Wang, Linhua Lan, Fan Yang, Shan Jiang, Haojun Xu, Chengfei Zhang, Guoren Zhou, Hongping Xia, Jinglin Xia
Publikováno v:
Genes and Diseases, Vol 9, Iss 3, Pp 789-796 (2022)
SIRT6 belongs to class III sirtuin family with NAD+-dependent histone deacetylase activities and controls multiple processes including aging, metabolism and inflammation. In recent years, increasing studies showed tumor suppressor role of SIRT6 in HC
Externí odkaz:
https://doaj.org/article/d8592aac749f4ef59a3b82d74f66ba23
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Spinal cord injury (SCI) causes severe neurological dysfunction leading to a devastating disease of the central nervous system that is associated with high rates of disability and mortality. Small extracellular vesicles (sEVs) derived from human umbi
Externí odkaz:
https://doaj.org/article/f7ef2e43af044958b5540a2a771c5fb3
Autor:
Zhongyi Wang, Tianlei Han, Haoqi Zhu, Jinxin Tang, Yanyang Guo, Yabing Jin, Yu Wang, Guilan Chen, Ning Gu, Chen Wang
Publikováno v:
Nanoscale Research Letters, Vol 16, Iss 1, Pp 1-16 (2021)
Abstract Nano-hydroxyapatite (nano-HA) has attracted substantial attention in the field of regenerative medicine. Endothelial cell (EC)-mesenchymal stem cell (MSC) interactions are necessary for bone reconstruction, but the manner in which nano-HA in
Externí odkaz:
https://doaj.org/article/82168c57640d40a2a79bf16854687a5a
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-11 (2021)
Abstract Background Osteoporosis seriously disturbs the life of people. Meanwhile, inhibition or weakening of osteogenic differentiation is one of the important factors in the pathogenesis of osteoporosis. It was reported that miR-27a-3p reduced the
Externí odkaz:
https://doaj.org/article/54b4ec72c7ef45e28c57a1396a1e2192
Publikováno v:
Cancer Management and Research, Vol Volume 13, Pp 287-296 (2021)
Xiang Miao, Yixiang Liu, Yuzhu Fan, Guoqiang Wang, Hongbo Zhu Department of General Surgery, Lianyungang Municipal Oriental Hospital, Lianyungang, Jiangsu 222042, People’s Republic of ChinaCorrespondence: Hongbo ZhuDepartment of General Surgery, Li
Externí odkaz:
https://doaj.org/article/72826f246a584ded922a3e0f1c5c5f38
Autor:
Qian Chen, Chencen Lai, Fa Chen, Yuanting Ding, Yiyuan Zhou, Songbai Su, Ruiqing Ni, Zhi Tang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Zinc is an essential trace element important for the physiological function of the central nervous system. The abnormal accumulation of zinc inside neurons may induce mitochondrial dysfunction and oxidative stress, which contribute to many brain dise
Externí odkaz:
https://doaj.org/article/6712dcef64854a3eb0f4af48b8553876
Autor:
Yongyong Yan, Jiantian Yang, Janak L. Pathak, Haiyan Wang, Jun Zha, Yongxiang Wei, Haibo Tang, Linhu Ge
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Lung adenocarcinoma is metastatic cancer with a high mortality rate. Circular RNAs (circRNAs) are a type of noncoding RNA and play a vital role in cancer progression. However, the expression and function of circRNAs in lung adenoc
Externí odkaz:
https://doaj.org/article/663f7711a7c54a24a87ec5391ffd39fe