Zobrazeno 1 - 10
of 12 314
pro vyhledávání: '"ERK1/2"'
Autor:
Agnieszka Rusak, Ewa Kątnik, Tomasz Górnicki, Christina Schmuttermaier, Krzysztof Kujawa, Aleksandra Piotrowska, Katarzyna Ratajczak-Wielgomas, Alicja Kmiecik, Andrzej Wojnar, Piotr Dzięgiel, Julia Kzhyshkowska
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Chitinase-like proteins have multiple biological functions that promote tumor growth, angiogenesis and metastasis. Expression of CHI3L2, which is similar in structure to CHI3L1, is detected in glioma cells and tumor-associated macrophages (T
Externí odkaz:
https://doaj.org/article/526f44a817694ad59ee3c6dec0040c88
Autor:
María-Milagros Rodríguez-Cano, María-Julia González-Gómez, Eva-María Monsalve, María-José M. Díaz-Guerra, Moustapha Kassem, Jorge Laborda, María-Luisa Nueda, Victoriano Baladrón
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-17 (2024)
Abstract Background C3H10T1/2 is a mesenchymal cell line capable of differentiating into osteoblasts, adipocytes and chondrocytes. The differentiation of these cells into osteoblasts is modulated by various transcription factors, such as RUNX2. Addit
Externí odkaz:
https://doaj.org/article/59d36de7aa4e4b6cadcd8748f02b433b
Autor:
Ahmed Z. El-Hashim, Maitham A. Khajah, Khaled Y. Orabi, Sowmya Balakrishnan, Hanan G. Sary, Ahmad M. Barakat
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 326-340 (2024)
AbstractContext Asthma presents a global health challenge. The main pharmacotherapy is synthetic chemicals and biological-based drugs that are costly, and have significant side effects. In contrast, use of natural products, such as onion (Allium cepa
Externí odkaz:
https://doaj.org/article/127ebbf353dd4b99ab74eeee4f30d609
Autor:
Hanfei Sun, Yi Feng, Shaoqin Tu, Jianwu Zhou, Yuxuan Wang, Jiaming Wei, Sai Zhang, Yuluan Hou, Yiting Shao, Hong Ai, Zheng Chen
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 268-278 (2024)
Introduction: Orthodontic tooth movement (OTM) involves complex interactions between mechanical forces and periodontal tissue adaptation, mainly mediated by periodontal ligament cells, including periodontal ligament stem cells (PDLSCs), osteoblasts,
Externí odkaz:
https://doaj.org/article/6cc6d0aaaebe44cbab15a4cf5a4298bd
Autor:
Reza Afarin, Negar Dinarvand, Hossein Azizi Dariuni, Ghazal Orak, Bahar Jaberian Asl, Reza Azizi, Azam Khedri
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 8, Pp 1015-1022 (2024)
Objective(s): Non-alcoholic fatty liver disease (NAFLD) is a chronic steatohepatitis disorder. If left untreated, it can progress to hepatocellular carcinoma. Several studies have shown that saroglitazar, a PPARα/γ dual agonist, and curcumin (the p
Externí odkaz:
https://doaj.org/article/55c5666d5f174315a54889ca5cc6a2ce
Autor:
Seyyed Moein Ebrahimi, Jahanbakhsh Asadi, Maryam Fattahian, Seyyed Mehdi Jafari, Mustafa Ghanadian
Publikováno v:
Research in Pharmaceutical Sciences, Vol 19, Iss 3, Pp 328-337 (2024)
Background and purpose: Herbal components, particularly sesquiterpenes, are progressively recognized as a crucial resource for developing effective therapeutic agents for breast cancer. In this study, the effect of a sesquiterpene lactone known as 8-
Externí odkaz:
https://doaj.org/article/92f61bff4f654b199f4bbc1997bb7d51
Autor:
Zhang Juan, Yang Lihong, Sun Yuqing, Zhang Li, Wang Yufei, Liu Ming, Li Xiujuan, Liang Yuxiang, Zhao Hong, Liu Zhizhen, Qiu Zhiyong, Zhang Ting, Xie Jun
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1483-1497 (2024)
Neural tube defects (NTDs) are characterized by the failure of neural tube closure during embryogenesis and are considered the most common and severe central nervous system anomalies during early development. Recent microRNA (miRNA) expression profil
Externí odkaz:
https://doaj.org/article/c5e1e66b3aec4441b8033ded51a706d9
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 6, Pp 475-483 (2024)
ERK1/2 is a key protein that mediates cell signal transduction, and it is involved in regulating biological processes such as chromatin remodeling, nuclear disintegration, proliferation, survival, metabolism, and cell migration and differentiation. I
Externí odkaz:
https://doaj.org/article/df39793afbe54add9d50f077e6256191
Autor:
Meijian Zhang, Emma Barroso, Lucía Peña, Patricia Rada, Ángela M. Valverde, Walter Wahli, Xavier Palomer, Manuel Vázquez-Carrera
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117303- (2024)
The role of peroxisome proliferator-activated receptor (PPAR)β/δ in hepatic fibrosis remains a subject of debate. Here, we examined the effects of a PPARβ/δ agonist on the pathogenesis of liver fibrosis and the activation of hepatic stellate cell
Externí odkaz:
https://doaj.org/article/bd3f461a588d498c847ef3d9ba500e5e
Autor:
Xuehua Zhang, Leilei Zhao, Jinlong Xiao, Yudi Wang, Yunmeng Li, Chaoqun Zhu, He Zhang, Yurui Zhang, Xiao Zhu, Yucui Dong
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/77e20cb594fc43e0a1608da4b4bede30