Zobrazeno 1 - 10
of 5 325
pro vyhledávání: '"ERBB2"'
Autor:
Melica Nourmoussavi Brodeur, Pier Selenica, Weining Ma, Sara Moufarrij, Christian Dagher, Thais Basili, Nadeem R. Abu‐Rustum, Carol Aghajanian, Qin Zhou, Alexia Iasonos, Lora H. Ellenson, Britta Weigelt, M. Herman Chui
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2356-2368 (2024)
Anti‐HER2 therapy is indicated for erb‐b2 receptor tyrosine kinase 2 (ERBB2)‐amplified/overexpressing endometrial carcinoma (EC). Mutations constitute another mode of ERBB2 activation, but only rare ERBB2‐mutated ECs have been reported. We so
Externí odkaz:
https://doaj.org/article/5b6c7d7bf2c04f0080d4461d3815a0fb
Autor:
Wu-niri Gao, Li-gang Chen, Lu-ri Bao, Ning He, Ta-la Hu, Can Lai, Rui-feng Xu, Xi-feng Wang, Jing-yuan Wang, Jian-rong Zhao, Yan Meng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Renal clear cell carcinoma (ccRCC) is a common parenchymal tumor of the kidney, and the discovery of biomarkers for early and effective diagnosis of ccRCC can improve the early diagnosis of patients and thus improve long-term survival. Erb-b
Externí odkaz:
https://doaj.org/article/64b325e61bc648b9b1ec65607511370b
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract This study aimed to investigate the effect and potential mechanism of evodiamine (EVO) on proliferation and apoptosis of nasopharyngeal carcinoma (NPC) cells. EVO inhibited proliferation, blocked cell cycle progression, and induced apoptosis
Externí odkaz:
https://doaj.org/article/dd9d35a2b116443c996e01e325c16baa
Autor:
Haoyue Qin, Huan Yan, Yangqian Chen, Qinqin Xu, Zhe Huang, Wenjuan Jiang, Zhan Wang, Li Deng, Xing Zhang, Lin Zhang, Nong Yang, Liang Zeng, Yongchang Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Limited data exists on the efficacy of immune checkpoint inhibitor (ICI) combinations in non-small-cell lung cancer (NSCLC) with uncommon driver alterations in genes such as ERBB2, BRAF, RET, and MET. This study retrospectively as
Externí odkaz:
https://doaj.org/article/c41750fbe4b64c9eb1c84566a8bc7ed4
Publikováno v:
Exploration of Medicine, Vol 5, Iss 4, Pp 530-543 (2024)
Aim: Present study was done to understand the dimerization of HER2/ERBB2 in normal and cancer cells using in-silico study. Methods: Pathway analysis was done using Reactome. Structure of HER2/ERBB2 protein was obtained from PDB database, and using S
Externí odkaz:
https://doaj.org/article/99612d68797e495581bf802cdd603cd1
Autor:
Anahita Shirvani, Sheida Sabbagh Seddigh, Mahshid Haddad, Farzad Amiri, Faezeh Fattahi, Ebrahim Alipour Limaee
Publikováno v:
International Journal of Scientific Research in Dental and Medical Sciences, Vol 6, Iss 2, Pp 74-84 (2024)
Background and aim: Breast cancer is one of the most common and worrying health problems of women in the world. The efficacy and safety of first-line and second-line/next-line treatments in women with HR + / HER2 − postmenopausal advanced breast ca
Externí odkaz:
https://doaj.org/article/da912b72d4284e55821025524541e285
Autor:
Hiroshi Ichikawa, Kenji Usui, Masaki Aizawa, Yoshifumi Shimada, Yusuke Muneoka, Yosuke Kano, Mika Sugai, Kazuki Moro, Yuki Hirose, Kohei Miura, Jun Sakata, Hiroshi Yabusaki, Satoru Nakagawa, Takashi Kawasaki, Hajime Umezu, Shujiro Okuda, Toshifumi Wakai
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Evaluation of human epidermal growth factor receptor 2 (HER2) overexpression caused by erb-b2 receptor tyrosine kinase 2 (ERBB2) amplification (AMP) by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) is es
Externí odkaz:
https://doaj.org/article/58024c73781244c2a550d82427280eba
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 204-30 (2024)
Borderline ovarian tumours (BOTs) show intriguing characteristics distinguishing them from other ovarian tumours. The aim of the systematic review was to analyse the spectrum of molecular changes found in BOTs and discuss their significance in the co
Externí odkaz:
https://doaj.org/article/61b5980ba5e544b385458d81e31cafd0
Autor:
Boon Yee Lim, Zexi Guo, Jing Quan Lim, Tun Kiat Ko, Elizabeth Chun Yong Lee, Bavani Kannan, Jing Yi Lee, Abner Herbert Lim, Zhimei Li, Cedric Chuan-Young Ng, Inny Busmanis, Jason Yongsheng Chan
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Extramammary Paget’s disease (EMPD) is a rare cancer that occurs within the epithelium of the skin, arising predominantly in areas with high apocrine gland concentration such as the vulva, scrotum, penis and perianal regions. He
Externí odkaz:
https://doaj.org/article/b048ce1268704ba08739b85c331f348a
Autor:
Yunjie Chen, Xuan Zhou, Xu Wang, Yuanbin Zhang, Jiayi Song, Yan Cai, Yizhuo Zhao, Lin Mei, Suyan Zhu, Xueqin Chen
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37085- (2024)
Fibroblast growth factor 20 (FGF20) is a member of the fibroblast growth factor family and involved in embryonic development and cardiac repair. This study aimed to explore the role of FGF20 in cardiac hypertrophy and the underlying molecular mechani
Externí odkaz:
https://doaj.org/article/a9310276506b4341a3654a85da1e6280