Zobrazeno 1 - 10
of 31
pro vyhledávání: '"EPSC, excitatory postsynaptic current"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Chronic stress can induce negative emotion states, including anxiety and depression, leading to sympathetic overactivation and disturbed physiological homeostasis in peripheral tissues. While anxiety-related neural circuitry integrates chronic stress
Externí odkaz:
https://doaj.org/article/648af9ef62b94b5fa9892d8533296c3c
Akademický článek
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Publikováno v:
Neurobiology of Pain, Vol 10, Iss, Pp 100078-(2021)
Neurobiology of Pain
Neurobiology of Pain
Highlights • Pregabalin attenuated the synaptic transmission in the central amygdala. • This effect was only observed in the latent inflammatory pain model. • Only the basolateral to central amygdala pathway was affected. • The potentiated in
Publikováno v:
IBRO Neuroscience Reports
Long-term cannabis use during adolescence has deleterious effects in brain that are largely ascribed to the activation of cannabinoid-1 receptors (CB1Rs) by delta-9-tetrahydrocannabinol (∆9-THC), the primary psychoactive compound in marijuana. Syst
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 3, Pp 198-209 (2016)
Molecular Metabolism, Vol 5, Iss 3, Pp 198-209 (2016)
Objective Humans and animals exposed to undernutrition (UN) during development often experience accelerated “catch-up” growth when food supplies are plentiful. Little is known about the mechanisms regulating early growth rates. We previously repo
Publikováno v:
Molecular Metabolism, Vol 36, Iss, Pp-(2020)
Molecular Metabolism
Molecular Metabolism
Objective Orexin (ORX) and melanin-concentrating hormone (MCH) neurons in the lateral hypothalamus are critical regulators of energy homeostasis and are thought to differentially contribute to diet-induced obesity. However, it is unclear whether the
Autor:
Laurence Coutellier, Chloe E. Page
Publikováno v:
EBioMedicine
An imbalance between neuronal excitation and inhibition represents a core feature in multiple neuropsychiatry disorders, necessitating the development of novel strategies to calibrate the excitatory–inhibitory balance of therapeutics. Here we ident
Autor:
Zhiping P. Pang, Weiping Han
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 32, Iss 5 (2012)
Bioscience Reports, Vol 32, Iss 5 (2012)
Energy homoeostasis, a co-ordinated balance of food intake and energy expenditure, is regulated by the CNS (central nervous system). The past decade has witnessed significant advances in our understanding of metabolic processes and brain circuitry wh
Autor:
Claire L.P. Garden, Maria M. Usowicz
Publikováno v:
Brain Research
Down syndrome (DS) is characterized by intellectual disability and impaired motor control. Lack of coordinated movement, poor balance, and unclear speech imply dysfunction of the cerebellum, which is known to be reduced in volume in DS. The principal
Autor:
Erika Polgár, Andrew J. Todd
Publikováno v:
Neuroscience
Although there is evidence that reduced inhibition in the spinal dorsal horn contributes to neuropathic pain, the mechanisms that underlie this are poorly understood. We have previously demonstrated that there is no loss of neurons from laminae I-III