Zobrazeno 1 - 10
of 62
pro vyhledávání: '"EPR, enhanced permeability and retention"'
Autor:
Fernando Novio
Publikováno v:
Molecules, Vol 25, Iss 15, p 3449 (2020)
Conventional cancer chemotherapy presents notable drug side effects due to non-selective action of the chemotherapeutics to normal cells. Nanoparticles decorated with receptor-specific ligands on the surface have shown an important role in improving
Externí odkaz:
https://doaj.org/article/409e1ebf894f4702a950bd4f7fd7513b
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3060-3091 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation and destruction of the lung air-blood barrier, leading to irreversible and substantial respiratory function damage. Patients with coronavirus disease 2019 (COVID-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7076f0b91326b1dc05f8b3eaf861f6
https://doi.org/10.1016/j.apsb.2021.04.023
https://doi.org/10.1016/j.apsb.2021.04.023
Autor:
Kenth Gustafsson, Rana Khalife, Konstantin Pildish, Rupali Dabas, Sofia Esteban Serna, Vladimir Kalinovskiy, Noelle Colant, Matas Deveikis, Alexander Van de Steen, Saverio Charalambous, Hasan Mustafa Khan, Stefanie Frank, Clare M. Robinson, Diana A. Catana
Publikováno v:
Synthetic and Systems Biotechnology, Vol 6, Iss 3, Pp 231-241 (2021)
Synthetic and Systems Biotechnology
Synthetic and Systems Biotechnology
The development of Drug Delivery Systems (DDS) has led to increasingly efficient therapies for the treatment and detection of various diseases. DDS use a range of nanoscale delivery platforms produced from polymeric of inorganic materials, such as mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89d5763f69c5fb3ee6055a67c29ad2d
http://www.sciencedirect.com/science/article/pii/S2405805X21000442
http://www.sciencedirect.com/science/article/pii/S2405805X21000442
Autor:
Liang Han, Chen Jiang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2306-2325 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and severely limits brain penetration of systemically administered drugs, resulting in ineffective drug therapy of brain diseases. However, during the onset and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a05eff9f72ac70fe48cb5ed9a111b5b
http://www.sciencedirect.com/science/article/pii/S2211383520308522
http://www.sciencedirect.com/science/article/pii/S2211383520308522
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 92-106 (2022)
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 92-106 (2022)
Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are restricted by several drawbacks, such as low drug loading, premature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a15ad3659d8f272ed8ada8a0844beb
http://europepmc.org/articles/PMC8799886
http://europepmc.org/articles/PMC8799886
Publikováno v:
Bioactive Materials
Bioactive Materials, Vol 6, Iss 7, Pp 1973-1987 (2021)
Bioactive Materials, Vol 6, Iss 7, Pp 1973-1987 (2021)
The tumor development and metastasis are closely related to the structure and function of the tumor microenvironment (TME). Recently, TME modulation strategies have attracted much attention in cancer immunotherapy. Despite the preliminary success of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9e3a12774af1e45fb188f205ad9bdc
https://doi.org/10.1016/j.bioactmat.2020.12.010
https://doi.org/10.1016/j.bioactmat.2020.12.010
Autor:
Huihui Zou, Zheng Wei, Chuanhui Song, Yu Cai, Sheng Chen, Gongyuan Liu, Wei Han, Jianchuan Ran, Xiteng Yin, Yufeng Wang, Chuanchao Tang, Guorong Zhang
Publikováno v:
Bioactive Materials, Vol 6, Iss 7, Pp 2144-2157 (2021)
Bioactive Materials
Bioactive Materials
Here, evodiamine (EVO) and the photosensitizer indocyanine green (ICG) were integrated into a liposomal nanoplatform for noninvasive diagnostic imaging and combinatorial therapy against oral squamous cell carcinoma (OSCC). EVO, as an active component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2baf72cc0ca972c4ef5911feeb618b74
https://doi.org/10.1016/j.bioactmat.2020.12.016
https://doi.org/10.1016/j.bioactmat.2020.12.016
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76811ce2af0ea0f7b3342230007c3c01
https://doi.org/10.1016/j.addr.2021.03.018
https://doi.org/10.1016/j.addr.2021.03.018
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2172-2196 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2172-2196 (2021)
Immunotherapy is a rapidly developing area of cancer treatment due to its higher specificity and potential for greater efficacy than traditional therapies. Immune cell modulation through the administration of drugs, proteins, and cells can enhance an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35de5eede84d436e4c319659616fdaea
http://europepmc.org/articles/PMC8424374
http://europepmc.org/articles/PMC8424374
Autor:
Shijun Zhang, Zhuomao Mo, Wen Ma, Ling Yu, Zhenjie Wang, Binhua Zou, Rui Sun, Yuanyuan Yang, Zhiqiang Yu, Meng Yu
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 2004-2015 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 2004-2015 (2021)
Hepatocellular carcinoma (HCC) has been known as the second common leading cancer worldwide, as it responds poorly to both chemotherapy and medication. Triptolide (TP), a diterpenoid triepoxide, is a promising treatment agent for its effective antica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228ab8ce9785b9f5dd7b0474572f6403
http://europepmc.org/articles/PMC8343191
http://europepmc.org/articles/PMC8343191