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pro vyhledávání: '"EPAC"'
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 4, Pp 429-436 (2024)
ABSTRACT Aims/Introduction Glucagon plays an essential role in hepatic glucogenesis by enhancing glycogen breakdown, inducing gluconeogenesis, and suppressing glycogenesis. Moreover, glucagon increases cyclic adenosine monophosphate (cAMP) levels, th
Externí odkaz:
https://doaj.org/article/0808263fc07f490bb97dc27e761b4477
Autor:
Vianello, Elena1 elena.vianello@unimi.it, Dozio, Elena1, Bandera, Francesco1,2, Schmitz, Gerd3, Nebuloni, Manuela4, Longhi, Erika4, Tacchini, Lorenza2, Guazzi, Marco1,2, Corsi Romanelli, Massimiliano Marco1,5
Publikováno v:
Scientific Reports. 1/21/2020, Vol. 10 Issue 1, p1-3. 3p.
Publikováno v:
Biology Bulletin. Mar2017, Vol. 44 Issue 2, p179-186. 8p.
Autor:
Kopperud, R. K.1,2, Rygh, C. Brekke1, Karlsen, T. V.1, Krakstad, C.1, Kleppe, R.1, Hoivik, E. A.1, Bakke, M.1, Tenstad, O.1, Selheim, F.1, Lidén, Å.1, Madsen, L.1,3, Pavlin, T.1, Taxt, T.1, Kristiansen, K.3, Curry, F.‐R. E.4, Reed, R. K.1,2, Døskeland, S. O.1 stein.doskeland@uib.no
Publikováno v:
Acta Physiologica. Feb2017, Vol. 219 Issue 2, p441-452. 12p.
Akademický článek
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Publikováno v:
Biomolecules, Vol 14, Iss 8, p 985 (2024)
Sulfonylureas (SUs) are a class of antidiabetic drugs widely used in the management of diabetes mellitus type 2. They promote insulin secretion by inhibiting the ATP-sensitive potassium channel in pancreatic β-cells. Recently, the exchange protein d
Externí odkaz:
https://doaj.org/article/c9fc437b02d84761aba4c7f8afe63f8b
Autor:
Schwede, Frank1, Bertinetti, Daniela2, Langerijs, Carianne N.3, Hadders, Michael A.4, Wienk, Hans5, Ellenbroek, Johanne H.6, de Koning, Eelco J. P.6,7, Bos, Johannes L.8, Herberg, Friedrich W.2, Genieser, Hans-Gottfried1, Janssen, Richard A. J.3, Rehmann, Holger8 h.rehmann@UMCutrecht.nl
Publikováno v:
PLoS Biology. Jan2015, Vol. 13 Issue 1, p1-26. 26p.
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 693 (2024)
Glucagon-like peptide-1 (GLP-1) is a multifunctional incretin hormone with various physiological effects beyond its well-characterized effect of stimulating glucose-dependent insulin secretion in the pancreas. An emerging role for GLP-1 and its recep
Externí odkaz:
https://doaj.org/article/33cc8a30467141bba6cbe0433082025d
Autor:
Gabriel Ferri, Lucía R. Fernández, Guillermo Di Mario, Daniel Musikant, Jorge A. Palermo, Martin M. Edreira
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Although the two drugs currently available for the treatment of Chagas disease, Benznidazole and Nifurtimox, have proven to be effective in the acute phase of the disease, the 60–90-day treatment leads to high toxicity and unwanted side effects, pr
Externí odkaz:
https://doaj.org/article/f0e04c9fb45346558fe3a9da3b49adb0
Autor:
Baljinnyam, Erdene1, Umemura, Masanari1,2, Chuang, Christine3, De Lorenzo, Mariana S.1, Iwatsubo, Mizuka1, Chen, Suzie4, Goydos, James S.5, Ishikawa, Yoshihiro1,2, Whitelock, John M.6, Iwatsubo, Kousaku1,2
Publikováno v:
Pigment Cell & Melanoma Research. Jul2014, Vol. 27 Issue 4, p611-620. 10p.