Zobrazeno 1 - 10
of 1 078
pro vyhledávání: '"EP300"'
Publikováno v:
Cell Stress, Vol 8, Pp 51-55 (2024)
In a recent issue in Nature Cell Biology, Sung Min Son et al. unveil a novel layer in the regulation of the mTORC1/autophagy axis by EP300 which can undergo nucleocytoplasmic shuttling in response to alterations in nutrient availability. The study hi
Externí odkaz:
https://doaj.org/article/ca94fec28cf44ffaa9fcbb29eb322eba
Autor:
Gautam Kundu, Maryam Ghasemi, Seungbin Yim, Ayanna Rohil, Cuiyan Xin, Leo Ren, Shraddha Srivastava, Akinwande Akinfolarin, Subodh Kumar, Gyan P. Srivastava, Venkata S. Sabbisetti, Gopal Murugaiyan, Amrendra K. Ajay
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2102 (2024)
Background: Signal transducer and activator of transcription 3 (STAT3) is a member of the cytoplasmic inducible transcription factors and plays an important role in mediating signals from cytokines, chemokines, and growth factors. We and others have
Externí odkaz:
https://doaj.org/article/1cf84321216f4f3fa08d8e61780970cb
Autor:
Yunhao Sun, Jian Sun, Kaijun Ying, Jinjin Chen, Tingting Chen, Leilei Tao, Weigang Bian, Limin Qiu
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27727- (2024)
Objective: To investigate the regulatory mechanism of EP300 in the interaction between SLC16A1-AS1 and TCF3 to activate the Wnt pathway, thereby promoting malignant progression in lung cancer. Methods: In lung cancer cell lines, SLC16A1-AS1 was knock
Externí odkaz:
https://doaj.org/article/9a379e7825c8482290caf36adf6aaaec
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol Volume 19, Pp 1763-1770 (2023)
Wanhong Peng,1,2,* Si Wang,1,* Minglan Yu,1 Tingting Wang,1 Rongfang He,1 Dongmei Liu,3 Dechao Chen,3 Xuemei Liang,1 Kezhi Liu,1 Bo Xiang1 1Department of Psychiatry, Laboratory of Neurological Diseases and Brain Function, Medical Laboratory C
Externí odkaz:
https://doaj.org/article/43e723c8708d4025ae50a642729f9394
Autor:
Chien‐Hsiu Li, Chih‐Yeu Fang, Ming‐Hsien Chan, Pei‐Jung Lu, Luo‐Ping Ger, Jan‐Show Chu, Yu‐Chan Chang, Chi‐Long Chen, Michael Hsiao
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 3, Pp 165-181 (2023)
Abstract Cancer progression is influenced by junctional adhesion molecule (JAM) family members. The relationship between JAM family members and different types of cancer was examined using The Cancer Genome Atlas dataset. mRNA levels of the F11R (F11
Externí odkaz:
https://doaj.org/article/3a1e9cee83ae4a3ab665b21686e958ba
Autor:
Panpan Guo, Mahmoud A.A Ibrahim, Hao Zhang, Yihao Wu, Fanxing Yin, Xiaoxu Zhang, Azad Hussain, Muhammad Naveel Riaz Dar, Deying Jiang, Yuemeng Li, Jian Zhang, Yanshuo Han
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 11, Pp 105227- (2023)
Background: The onset of abdominal aortic aneurysm (AAA) is caused by local dilatation of the infrarenal abdominal aorta. Curcumin can affect the polarization and function of macrophage subsets in the context of vascular diseases. Curcumin, a natural
Externí odkaz:
https://doaj.org/article/5bdf8f6141c04d899ad2a7cf054e66f1
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract Background Rubinstein-Taybi syndrome (RSTS) is characterized by distinctive facial features, broad and often angulated thumbs and halluces, short stature, and moderate-to-severe intellectual disability, classified into two types RSTS1 (CREBB
Externí odkaz:
https://doaj.org/article/4233d8c88e5f4a66b53509fa79f87fa6
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Background Rubinstein–Taybi syndrome (RSTS) is an extremely rare autosomal dominant inheritable disorder caused by CREBBP and EP300 mutations, while atypical RSTS harbouring variant from the same genes but not obvious resembling RSTS. Ther
Externí odkaz:
https://doaj.org/article/77366f2ebdac43679fc52c20e46d86b0
Autor:
Arnault Tauziède-Espariat, Emmanuelle Uro-Coste, Philipp Sievers, Yvan Nicaise, Cassandra Mariet, Aurore Siegfried, Gaëlle Pierron, Delphine Guillemot, Joseph Benzakoun, Johan Pallud, Margaux Roques, Fabrice Bonneville, Delphine Larrieu-Ciron, Patrick Chaynes, Raphaël Saffroy, Jocelyne Hamelin, Lauren Hasty, Alice Métais, Fabrice Chrétien, Marcel Kool, Johannes Gojo, Pascale Varlet, RENOCLIP-LOC
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-7 (2023)
Abstract The Central Nervous System (CNS) tumor with BCOR internal tandem duplication (ITD) has recently been added as a novel embryonal histomolecular tumor type to the 2021 World Health Organization (WHO) Classification of CNS Tumors. In addition,
Externí odkaz:
https://doaj.org/article/5643c29948e34ec9a8b2aca251686103
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 9, Pp n/a-n/a (2023)
Abstract Background Rubinstein–Taybi syndrome (RSTS) is a rare autosomal‐dominant genetic disease caused by variants of CREBBP (RSTS1) or EP300 (RSTS2) gene. RSTS2 is much less common, with less than 200 reported cases worldwide to date. More rep
Externí odkaz:
https://doaj.org/article/bc252736e63d4e5da79a5d7046df2ba0