Zobrazeno 1 - 10
of 675
pro vyhledávání: '"ENPP1"'
Autor:
Hafiza Noor Ul Ayan, Yvonne Nitschke, Abdul Razzaq Mughal, Holger Thiele, Naveed Altaf Malik, Ijaz Hussain, Syed Muhammad Ijlal Haider, Frank Rutsch, Jeanette Erdmann, Muhammad Tariq, Zouhair Aherrahrou, Ilyas Ahmad
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) plays a critical role by converting extracellular ATP to AMP, generating extracellular PPi, a potential inhibitor of calcification. Pathogenic variants in the ENPP1 cause generalized
Externí odkaz:
https://doaj.org/article/99f8a7384195499cb0725455db5cf3c2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Human periodontal ligament stem cells (hPDLSCs) differentiate into periodontal ligament (PDL) fibroblasts, osteoblasts, and cementoblasts. To identify inducers of PDL fibroblastic differentiation, monoclonal antibody series were developed a series of
Externí odkaz:
https://doaj.org/article/70fb797b986849c494d27f8ad46389ba
Autor:
Yang Zhou, Lili Bao, Shengkai Gong, Geng Dou, Zihan Li, Zhengyan Wang, Lu Yu, Feng Ding, Huan Liu, Xiayun Li, Siying Liu, Xiaoshan Yang, Shiyu Liu
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Radiation enteritis is the most common complication of pelvic radiotherapy, but there is no effective prevention or treatment drug. Apoptotic T cells and their products play an important role in regulating inflammation and maintaining physio
Externí odkaz:
https://doaj.org/article/a1052535ec444f0e941c6577113b6191
Autor:
Yu An, Jinchao Zhu, Qihui Xie, Jianzhou Feng, Yanli Gong, Qian Fan, Jiao Cao, Zhi Huang, Weixiong Shi, Qingyuan Lin, Lingling Wu, Chaoyong Yang, Tianhai Ji
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract To evade immune surveillance, tumor cells express ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) on the surface of their membrane, which degrades extracellular cyclic GMP‐AMP (cGAMP), thereby inhibiting the cyclic GMP‐AMP syn
Externí odkaz:
https://doaj.org/article/5eb262401ddb40739bc313b105a7ca39
Publikováno v:
Open Medicine, Vol 18, Iss 1, Pp 1-11 (2023)
This study aims to investigate the impact of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) on vascular calcification in rats. The rationale behind studying ENPP1’s role in vascular calcification lies in its potential to modulate calcif
Externí odkaz:
https://doaj.org/article/c0d0d14519f546979c71328bac7faa50
Autor:
Ida Tomomi, Hiroyuki Kanzaki, Miho Shimoyama, Syunnosuke Tohyama, Misao Ishikawa, Yuta Katsumata, Chihiro Arai, Satoshi Wada, Shugo Manase, Hiroshi Tomonari
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 896 (2024)
Calcification plays a key role in biological processes, and breakdown of the regulatory mechanism results in a pathological state such as ectopic calcification. We hypothesized that ENPP1, the enzyme that produces the calcification inhibitor pyrophos
Externí odkaz:
https://doaj.org/article/00eae710e6a04914befc4048dbd0aa34
Akademický článek
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Autor:
Abdur Rauf, Zuneera Akram, Muhammad Naveed, Najla AlMasoud, Taghrid S. Alomar, Muhammad Saleem, Abdul Waheed, Giovanni Ribaudo
Publikováno v:
Chemistry, Vol 5, Iss 4, Pp 2094-2103 (2023)
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) regulates skeletal and soft tissue mineralization by hydrolyzing nucleotide triphosphates and cyclic nucleotides, and is involved in the modulation of immune system. In fact, ENPP1 degrades 2
Externí odkaz:
https://doaj.org/article/9cf00371909a4f7584e27b6690e20c1c
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
Abstract is missing (Quiz)
Externí odkaz:
https://doaj.org/article/4ebc55bb7a984cc3a9a818a639de7abd
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Objective and background The deficiency of ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1) causes the phenotype similar to knee osteoarthritis (OA). However, the molecular mechanism is poorly understood. Method The global deletion
Externí odkaz:
https://doaj.org/article/b14f576a9c9e4508a1f0d725f2a74121