Zobrazeno 1 - 10
of 512
pro vyhledávání: '"ENO1"'
Autor:
Yun Tian, Jiafan Guo, Lipeng Mao, Zhixi Chen, Xingwei Zhang, Yangqiu Li, Yikai Zhang, Xianfeng Zha, Oscar Junhong Luo
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Quiescent self-renewal of leukemia stem cells (LSCs) and resistance to conventional chemotherapy are the main factors leading to relapse of acute myeloid leukemia (AML). Alpha-enolase (ENO1), a key glycolytic enzyme, has been show
Externí odkaz:
https://doaj.org/article/1b76bb0bad774a7c84ce0c6890428e9f
Autor:
Zeng Kangkang, Yin Hao
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 1292-9 (2024)
Externí odkaz:
https://doaj.org/article/b93c309d783e4f06a855336b8983ee98
Autor:
Yuexin Wang, Na Li, Guanda Liang, Luyang Wang, Xiaotian Zhang, Zhaohui Cui, Xiaoying Li, Sumei Zhang, Longxian Zhang
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Background Cryptosporidium parvum is an apicomplexan zoonotic parasite causing the diarrheal illness cryptosporidiosis in humans and animals. To invade the host intestinal epithelial cells, parasitic proteins expressed on the surface of spor
Externí odkaz:
https://doaj.org/article/fc68176b72b0490db64a691d3b50208b
Autor:
Baoxiang Chen, Yanrong Deng, Yuntian Hong, Lifang Fan, Xiang Zhai, Heng Hu, Siyuan Yin, Quanjiao Chen, Xiaoyu Xie, Xianghai Ren, Jianhong Zhao, Congqing Jiang
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract The RNA modification, 5‐methylcytosine (m5C), has recently gained prominence as a pivotal post‐transcriptional regulator of gene expression, intricately intertwined with various tumorigenic processes. However, the exact mechanisms govern
Externí odkaz:
https://doaj.org/article/8571c9db05ef4a2ebf43a3af3bc84355
Anti-ENO1 antibody combined with metformin against tumor resistance: a novel antibody-based platform
Publikováno v:
PeerJ, Vol 12, p e16817 (2024)
Background Antibody-based platforms (i.e., ADC) have emerged as one of the most encouraging tools for the cancer resistance caused by cancer stem cells (CSCs) enrichment. Our study might provide a promising therapeutic direction against drug resistan
Externí odkaz:
https://doaj.org/article/2ccf73ec7e4a4014aa6c3c72707ade67
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-18 (2023)
Abstract Background Despite improvements in prognosis due to advances in treatment, including surgery, genetic screening, and molecular targeted therapy, the outcomes of ovarian cancer (OC) remain unsatisfactory. Internal mRNA modifications are extre
Externí odkaz:
https://doaj.org/article/a5c8141803824d6aa40a0e9c3ed4908b
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 9, Pp 904-915 (2023)
Abstract Cancer stem cells (CSCs), a rare subset of tumor cells, have been recognized as promotive role on tumor initiation and propagation. Among, aerobic glycolysis, widely clarified in multiple tumor cells, is the key for maintaining cancer stemne
Externí odkaz:
https://doaj.org/article/5b04ab57b7da496db77cd65a5b4bb5eb
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100750- (2023)
Aerobic glycolysis is a hallmark property of cancer metabolism. Enolase is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate into phosphoenolpyruvate. In mammals, enolases exist in three isoforms, encoded by the genes ENO1, ENO2
Externí odkaz:
https://doaj.org/article/c7ff07d6b025486c97653f14157d05a6
Autor:
Hyejung Jo, Seulgi Shin, Tomoyo Agura, Seoyoun Jeong, Hyovin Ahn, Junmyung Lee, Yejin Kim, Jae Seung Kang
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 531 (2024)
Interleukin (IL)-32 is produced by T lymphocytes, natural killer cells, monocytes, and epithelial cells. IL-32 induces the production of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, IL-1β, IL-6, and IL-8, and IL-32 expression i
Externí odkaz:
https://doaj.org/article/54f4222161aa49be9ab4f8d09af9bdc3
Publikováno v:
PeerJ, Vol 11, p e16140 (2023)
Background Metabolic reprogramming is a key marker in the occurrence and development of tumors. This process generates more reactive oxygen species (ROS), promoting the development of oxidative stress. To prevent ROS from harming tumor cells, tumor c
Externí odkaz:
https://doaj.org/article/7418457a94884eada22356a241900775