Zobrazeno 1 - 10
of 41
pro vyhledávání: '"ENGAGE Consortium"'
Autor:
Momoko Horikoshi, Reedik Mӓgi, Martijn van de Bunt, Ida Surakka, Antti-Pekka Sarin, Anubha Mahajan, Letizia Marullo, Gudmar Thorleifsson, Sara Hӓgg, Jouke-Jan Hottenga, Claes Ladenvall, Janina S Ried, Thomas W Winkler, Sara M Willems, Natalia Pervjakova, Tõnu Esko, Marian Beekman, Christopher P Nelson, Christina Willenborg, Steven Wiltshire, Teresa Ferreira, Juan Fernandez, Kyle J Gaulton, Valgerdur Steinthorsdottir, Anders Hamsten, Patrik K E Magnusson, Gonneke Willemsen, Yuri Milaneschi, Neil R Robertson, Christopher J Groves, Amanda J Bennett, Terho Lehtimӓki, Jorma S Viikari, Johan Rung, Valeriya Lyssenko, Markus Perola, Iris M Heid, Christian Herder, Harald Grallert, Martina Müller-Nurasyid, Michael Roden, Elina Hypponen, Aaron Isaacs, Elisabeth M van Leeuwen, Lennart C Karssen, Evelin Mihailov, Jeanine J Houwing-Duistermaat, Anton J M de Craen, Joris Deelen, Aki S Havulinna, Matthew Blades, Christian Hengstenberg, Jeanette Erdmann, Heribert Schunkert, Jaakko Kaprio, Martin D Tobin, Nilesh J Samani, Lars Lind, Veikko Salomaa, Cecilia M Lindgren, P Eline Slagboom, Andres Metspalu, Cornelia M van Duijn, Johan G Eriksson, Annette Peters, Christian Gieger, Antti Jula, Leif Groop, Olli T Raitakari, Chris Power, Brenda W J H Penninx, Eco de Geus, Johannes H Smit, Dorret I Boomsma, Nancy L Pedersen, Erik Ingelsson, Unnur Thorsteinsdottir, Kari Stefansson, Samuli Ripatti, Inga Prokopenko, Mark I McCarthy, Andrew P Morris, ENGAGE Consortium
Publikováno v:
PLoS Genetics, Vol 11, Iss 7, p e1005230 (2015)
Reference panels from the 1000 Genomes (1000G) Project Consortium provide near complete coverage of common and low-frequency genetic variation with minor allele frequency ≥0.5% across European ancestry populations. Within the European Network for G
Externí odkaz:
https://doaj.org/article/4951b009b4df434e8a71bfb9ab373a22
Autor:
Ida Surakka, Aaron Isaacs, Lennart C Karssen, Pirkka-Pekka P Laurila, Rita P S Middelberg, Emmi Tikkanen, Janina S Ried, Claudia Lamina, Massimo Mangino, Wilmar Igl, Jouke-Jan Hottenga, Vasiliki Lagou, Pim van der Harst, Irene Mateo Leach, Tõnu Esko, Zoltán Kutalik, Nicholas W Wainwright, Maksim V Struchalin, Antti-Pekka Sarin, Antti J Kangas, Jorma S Viikari, Markus Perola, Taina Rantanen, Ann-Kristin Petersen, Pasi Soininen, Asa Johansson, Nicole Soranzo, Andrew C Heath, Theodore Papamarkou, Inga Prokopenko, Anke Tönjes, Florian Kronenberg, Angela Döring, Fernando Rivadeneira, Grant W Montgomery, John B Whitfield, Mika Kähönen, Terho Lehtimäki, Nelson B Freimer, Gonneke Willemsen, Eco J C de Geus, Aarno Palotie, Manj S Sandhu, Dawn M Waterworth, Andres Metspalu, Michael Stumvoll, André G Uitterlinden, Antti Jula, Gerjan Navis, Cisca Wijmenga, Bruce H R Wolffenbuttel, Marja-Riitta Taskinen, Mika Ala-Korpela, Jaakko Kaprio, Kirsten O Kyvik, Dorret I Boomsma, Nancy L Pedersen, Ulf Gyllensten, James F Wilson, Igor Rudan, Harry Campbell, Peter P Pramstaller, Tim D Spector, Jacqueline C M Witteman, Johan G Eriksson, Veikko Salomaa, Ben A Oostra, Olli T Raitakari, H-Erich Wichmann, Christian Gieger, Marjo-Riitta Järvelin, Nicholas G Martin, Albert Hofman, Mark I McCarthy, Leena Peltonen, Cornelia M van Duijn, Yurii S Aulchenko, Samuli Ripatti, ENGAGE Consortium
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002333 (2011)
Recent genome-wide association (GWA) studies described 95 loci controlling serum lipid levels. These common variants explain ∼25% of the heritability of the phenotypes. To date, no unbiased screen for gene-environment interactions for circulating l
Externí odkaz:
https://doaj.org/article/b59698eee7fa4c7c9f51db92a8ffc2f7
Autor:
Jussi Naukkarinen, Ida Surakka, Kirsi H Pietiläinen, Aila Rissanen, Veikko Salomaa, Samuli Ripatti, Hannele Yki-Järvinen, Cornelia M van Duijn, H-Erich Wichmann, Jaakko Kaprio, Marja-Riitta Taskinen, Leena Peltonen, ENGAGE Consortium
Publikováno v:
PLoS Genetics, Vol 6, Iss 6, p e1000976 (2010)
To get beyond the "low-hanging fruits" so far identified by genome-wide association (GWA) studies, new methods must be developed in order to discover the numerous remaining genes that estimates of heritability indicate should be contributing to compl
Externí odkaz:
https://doaj.org/article/c2f8cc33a7ba400b8f4ea5c5142f2e00
Autor:
Melanie Kolz, Toby Johnson, Serena Sanna, Alexander Teumer, Veronique Vitart, Markus Perola, Massimo Mangino, Eva Albrecht, Chris Wallace, Martin Farrall, Asa Johansson, Dale R Nyholt, Yurii Aulchenko, Jacques S Beckmann, Sven Bergmann, Murielle Bochud, Morris Brown, Harry Campbell, EUROSPAN Consortium, John Connell, Anna Dominiczak, Georg Homuth, Claudia Lamina, Mark I McCarthy, ENGAGE Consortium, Thomas Meitinger, Vincent Mooser, Patricia Munroe, Matthias Nauck, John Peden, Holger Prokisch, Perttu Salo, Veikko Salomaa, Nilesh J Samani, David Schlessinger, Manuela Uda, Uwe Völker, Gérard Waeber, Dawn Waterworth, Rui Wang-Sattler, Alan F Wright, Jerzy Adamski, John B Whitfield, Ulf Gyllensten, James F Wilson, Igor Rudan, Peter Pramstaller, Hugh Watkins, PROCARDIS Consortium, Angela Doering, H-Erich Wichmann, KORA Study, Tim D Spector, Leena Peltonen, Henry Völzke, Ramaiah Nagaraja, Peter Vollenweider, Mark Caulfield, WTCCC, Thomas Illig, Christian Gieger
Publikováno v:
PLoS Genetics, Vol 5, Iss 6, p e1000504 (2009)
Elevated serum uric acid levels cause gout and are a risk factor for cardiovascular disease and diabetes. To investigate the polygenetic basis of serum uric acid levels, we conducted a meta-analysis of genome-wide association scans from 14 studies to
Externí odkaz:
https://doaj.org/article/ff4cc331981e449292132db7bb00d13e
Autor:
Ojha, Juhi, Codd, Veryan, Nelson, Christopher P, Samani, Nilesh J, Smirnov, Ivan V, Madsen, Nils R, Hansen, Helen M, de Smith, Adam J, Bracci, Paige M, Wiencke, John K, Wrensch, Margaret R, Wiemels, Joseph L, Walsh, Kyle M, ENGAGE Consortium Telomere Group
Publikováno v:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol 25, iss 7
BackgroundChronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. Shorter mean telomere length in leukemic cells has been associated with more aggressive disease. Germline polymorphisms in telomere maintenance genes affec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::28bfe42b836af26c5f32369b4fffbd5c
https://escholarship.org/uc/item/8z44m8r3
https://escholarship.org/uc/item/8z44m8r3
Autor:
Walsh, Kyle M, Whitehead, Todd P, de Smith, Adam J, Smirnov, Ivan V, Park, Minsun, Endicott, Alyson A, Francis, Stephen S, Codd, Veryan, ENGAGE Consortium Telomere Group, Samani, Nilesh J, Metayer, Catherine, Wiemels, Joseph L
Publikováno v:
Carcinogenesis, vol 37, iss 6
Aberrant telomere lengthening is an important feature of cancer cells in adults and children. In addition to somatic mutations, germline polymorphisms in telomere maintenance genes impact telomere length. Whether these telomere-associated polymorphis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9a1f87a9da15710833cfbd1ff54d072d
https://escholarship.org/uc/item/9cr3q4z9
https://escholarship.org/uc/item/9cr3q4z9
Autor:
Fall T, Hxe4gg S, Mxe4gi R, Ploner A, Fischer K, Horikoshi M, Sarin AP, Thorleifsson G, Ladenvall C, Kals M, Kuningas M, Draisma HH, Ried JS, van Zuydam NR, Huikari V, Hottenga JJ, Willemsen G, Penninx BW, Boomsma DI, de Geus EJ, Morris AD, Groop L, Jxe4rvelin MR, Salomaa V, Vartiainen E, Hofman A, Ripatti S, Metspalu A, Thorsteinsdottir U, Stefansson K, Pedersen NL, McCarthy MI, Ingelsson E, Prokopenko I, European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium, European Network for Genetic, Genomic Epidemiology (ENGAGE) consortium
Publikováno v:
BDJ
Akademický článek
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Autor:
Walsh, Kyle M, Codd, Veryan, Smirnov, Ivan V, Rice, Terri, Decker, Paul A, Hansen, Helen M, Kollmeyer, Thomas, Kosel, Matthew L, Molinaro, Annette M, McCoy, Lucie S, Bracci, Paige M, Cabriga, Belinda S, Pekmezci, Melike, Zheng, Shichun, Wiemels, Joseph L, Pico, Alexander R, Tihan, Tarik, Berger, Mitchell S, Chang, Susan M, Prados, Michael D, Lachance, Daniel H, O'Neill, Brian Patrick, Sicotte, Hugues, Eckel-Passow, Jeanette E, ENGAGE Consortium Telomere Group, van der Harst, Pim, Wiencke, John K, Samani, Nilesh J, Jenkins, Robert B, Wrensch, Margaret R
Publikováno v:
Nature genetics, vol 46, iss 7
Glioma, the most common central nervous system cancer in adults, has poor prognosis. Here we identify a new SNP associated with glioma risk, rs1920116 (near TERC), that reached genome-wide significance (Pcombined = 8.3 × 10(-9)) in a meta-analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3650ecf1ef69d713bd9f49ac02daebf0
https://escholarship.org/uc/item/6d11m6zz
https://escholarship.org/uc/item/6d11m6zz
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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