Knockdown of RhoE Expression Enhances TGF-β-Induced EMT (epithelial-to-mesenchymal transition) in Cervical Cancer HeLa Cells

Autor: Masayoshi Imagawa, Rina Komada, Makoto Nishizuka

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 19
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4697 (2019)

Cervical cancer with early metastasis of the primary tumor is associated with poor prognosis and poor therapeutic outcomes. Since epithelial-to-mesenchymal transition (EMT) plays a role in acquisition of the ability to invade the pelvic lymph nodes a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141d4218642ca679b72a5594a059528e
https://pubmed.ncbi.nlm.nih.gov/31546735

Epigenetic Regulation of EMT (Epithelial to Mesenchymal Transition) and Tumor Aggressiveness: A View on Paradoxical Roles of KDM6B and EZH2.

Autor: Lachat C; Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, INSERM, EFS BFC, UMR1098, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France., Boyer-Guittaut M; Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, INSERM, EFS BFC, UMR1098, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France.; DImaCell Platform, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France., Peixoto P; Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, INSERM, EFS BFC, UMR1098, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France.; EPIGENEXP Platform, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France., Hervouet E; Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, INSERM, EFS BFC, UMR1098, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France.; DImaCell Platform, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France.; EPIGENEXP Platform, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France.

Publikováno v: Epigenomes [Epigenomes] 2018 Dec 20; Vol. 3 (1). Date of Electronic Publication: 2018 Dec 20.

The relationship between matriptase and EMT (epithelial to mesenchymal transition) in arecoline induced oral cancer

Autor: 張益捷 CHANG, I-CHIEH, 張益捷

104
In taiwan, areca quid chewering is a common behavior of many people. According to epidemiological analysis, it has been demonstrated that areca quid chewing is the main etiological factor for the development of oral squamous cell carcinoma (

Externí odkaz: http://ndltd.ncl.edu.tw/handle/96792561248995463209

TIMP1 Indicates Poor Prognosis of Renal Cell Carcinoma and Accelerates Tumorigenesis via EMT Signaling Pathway

Autor: Yi Shou, Yuenan Liu, Jiaju Xu, Jingchong Liu, Tianbo Xu, Junwei Tong, Lilong Liu, Yaxin Hou, Di Liu, Hongmei Yang, Gong Cheng, Xiaoping Zhang

Publikováno v: Frontiers in Genetics, Vol 13 (2022)

Renal cell carcinoma (RCC) is one of the most common malignancies in the urinary system. The mortality of advanced RCC remains high despite advances in systemic therapy of RCC. Considering the misdiagnosis of early-stage RCC, the identification of ef

Externí odkaz: https://doaj.org/article/041c431033bb48ffb5bb80aa425bc492

Transforming Growth Factor-β: An Agent of Change in the Tumor Microenvironment

Autor: Christina H. Stuelten, Ying E. Zhang

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Transforming Growth Factor-β (TGF-β) is a key regulator of embryonic development, adult tissue homeostasis, and lesion repair. In tumors, TGF-β is a potent inhibitor of early stage tumorigenesis and promotes late stage tumor progression and metast

Externí odkaz: https://doaj.org/article/17b52cfd64d64ea6bfedf4a60b382fd4