Zobrazeno 1 - 10
of 136
pro vyhledávání: '"EMAST"'
Autor:
August Fiegl, Olaf Wendler, Johannes Giedl, Nadine T. Gaisa, Georg Richter, Valentina Campean, Maximilian Burger, Femke Simmer, Iris Nagtegaal, Bernd Wullich, Simone Bertz, Arndt Hartmann, Robert Stoehr
Publikováno v:
Current Oncology, Vol 31, Iss 10, Pp 5752-5761 (2024)
Penile squamous cell carcinoma (pSCC) is a rare malignancy with a global incidence ranging from 0.1 to 0.7 per 100,000 males. Prognosis is generally favorable for localized tumors, but metastatic pSCC remains challenging, with low survival rates. The
Externí odkaz:
https://doaj.org/article/14907560a88b43e28cf14c2e4cc6ef12
Autor:
Amir Torshizi Esfahani, Somayeh Mohammadpour, Pooya Jalali, Alireza Yaghoobi, Raana Karimpour, Soha Torkamani, Ali Pardakhtchi, Zahra Salehi, Ehsan Nazemalhosseini-Mojarad
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Abnormal angiogenesis leads to tumor progression and metastasis in colorectal cancer (CRC). This study aimed to elucidate the association between angiogenesis-related genes, including VEGF-A, ANGPT-1, and ANGPT-2 with both metastatic and mic
Externí odkaz:
https://doaj.org/article/0343cf12e21f4834a95623cdab687d51
Akademický článek
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Akademický článek
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Autor:
Natalya Risinskaya, Yana Mangasarova, Elena Nikulina, Yana Kozhevnikova, Julia Chabaeva, Anna Yushkova, Aminat Magomedova, Sergey Kulikov, Hunan Julhakyan, Sergey Kravchenko, Andrey Sudarikov
Publikováno v:
Current Oncology, Vol 29, Iss 5, Pp 3449-3459 (2022)
Primary mediastinal B-cell lymphoma (PMBCL) is the only non-Hodgkin’s lymphoma variant responding to immune checkpoint inhibitor (ICI) therapy, approximately in half of the cases; however, no molecular markers predicting a response to ICI therapy i
Externí odkaz:
https://doaj.org/article/9555a9124a0b40c1a703bc6701349aa0
Autor:
Anna‐Lina Herz, Sarah Wisser, Meike Kohlruss, Julia Slotta‐Huspenina, Moritz Jesinghaus, Bianca Grosser, Katja Steiger, Alexander Novotny, Alexander Hapfelmeier, Thomas Schmidt, Matthias M Gaida, Wilko Weichert, Gisela Keller
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 3, Pp 233-244 (2022)
Abstract We investigated the clinical impact of elevated microsatellite instability at selected tetranucleotide (EMAST) repeats in the context of neoadjuvant chemotherapy (CTx) in gastric/gastro‐oesophageal adenocarcinomas. We analysed 583 resected
Externí odkaz:
https://doaj.org/article/e5e6877fff83436aa6d11d902a591f00
Akademický článek
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Autor:
Yoshiki Okita, Minoru Koi, Koki Takeda, Ryan Ross, Bhramar Mukherjee, Erika Koeppe, Elena M. Stoffel, Joseph A. Galanko, Amber N. McCoy, Temitope O. Keku, Yoshinaga Okugawa, Takahito Kitajima, Yuji Toiyama, Eric Martens, John M. Carethers
Publikováno v:
Gut Pathogens, Vol 12, Iss 1, Pp 1-5 (2020)
Abstract Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylation phenotype (CIMP). Fn infect
Externí odkaz:
https://doaj.org/article/99ec52fbc04644c492b5dea7f470933d
Autor:
Shih‐Ching Chang, Yuan‐Tzu Lan, Pei‐Ching Lin, Shung‐Haur Yang, Chien‐Hsing Lin, Wen‐Yi Liang, Wei‐Shone Chen, Jeng‐Kai Jiang, Jen‐Kou Lin
Publikováno v:
Cancer Medicine, Vol 9, Iss 2, Pp 476-486 (2020)
Abstract Background We assumed that targeted next‐generation sequencing (NGS) of mismatch repair‐associated genes could improve the detection of driving mutations in colorectal cancers (CRC) with microsatellite instability (MSI) and microsatellit
Externí odkaz:
https://doaj.org/article/e7e96e7587144de7b6c1dab4f8919152
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 689-704 (2020)
Background & Aims: Fifty percent of colorectal cancers show elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) and are associated with inflammation, metastasis, and poor patient outcome. EMAST results from interleukin 6
Externí odkaz:
https://doaj.org/article/9fbbeccda44f4ad790672aae19c88d4d