Acinetobacter quorum sensing contributes to inflammation-induced inhibition of orthopaedic implant osseointegration

Autor: H Choe, BS Hausman, KM Hujer, O Akkus, PN Rather, Z Lee, RA Bonomo, EM Greenfield

Publikováno v: European Cells & Materials, Vol 43, Pp 267-276 (2022)

Implant infection impairs osseointegration of orthopaedic implants by inducing inflammation. Acinetobacter spp. are increasingly prevalent multi-drug resistant bacteria that can cause osteomyelitis. Acinetobacter spp. can also cause inflammation and

Externí odkaz: https://doaj.org/article/c48469a1b84846fb9000b8a7bad2d0bb

Biofilm Formation is Durably Prevented on Pre-Fabricated Antibiotic Cement Spacers Compared to Cobalt Chrome and Polyethylene.

Autor: Higashihira S; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, Indiana; Department of Orthopaedic Surgery, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan., Simpson SJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, Indiana., Arnold CJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Deckard ER; Indiana Joint Replacement Institute, Indianapolis, Indiana., Meneghini RM; Indiana Joint Replacement Institute, Indianapolis, Indiana., Greenfield EM; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, Indiana., Buller LT; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana.

Publikováno v: The Journal of arthroplasty [J Arthroplasty] 2024 Sep 02. Date of Electronic Publication: 2024 Sep 02.

The 2023 Orthopedic Research Society's international consensus meeting on musculoskeletal infection: Summary from the in vitro section.

Autor: Hickok NJ; Department of Orthopaedic Surgery, Department of Biochemistry & Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Li B; Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia, USA., Oral E; Harris Orthopaedic Laboratory, Department of Orthopaedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Zaat SAJ; Department of Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Armbruster DA; DePuy Synthes Biomaterials, West Chester, Pennsylvania, USA., Atkins GJ; Centre for Orthopaedic and Trauma Research, University of Adelaide, Adelaide, South Australia, Australia., Chen AF; Department of Orthopaedics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Coraça-Huber DC; Research Laboratory for Implant Associated Infections (Biofilm Lab), University Hospital for Orthopedics and Traumatology, Experimental Orthopaedics, Medical University of Innsbruck, Innsbruck, Austria., Dai T; Harvard Medical School, Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Greenfield EM; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indiana Center for Musculoskeletal Health, Indianapolis, Indiana, USA., Kasinath R; DePuy Synthes Biomaterials, Warsaw, Indiana, USA., Libera M; Department of Chemical Engineering and Materials Science, Stevens Institute of Technology, Hoboken, New Jersey, USA., Marques CNH; Department of Biological Sciences, Binghamton Biofilm Research Center, Binghamton University, Binghamton, New York, USA., Moriarty TF; AO Research Institute Davos, Davos, Switzerland., Scott Phillips K; Laboratory of Analytical Chemistry, Division of Biological Standards and Quality Control, Office of Compliance and Biologics Quality, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Raghuraman K; Enovis, Austin, Texas, USA., Ren D; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York, USA., Rimondini L; Department of Health Sciences, Università del Piemonte Orientale, Novara, Italy., Saeed K; University Hospital Southampton NHS Foundation Trust, Winchester and Basingstoke, UK.; University of Southampton, Southampton, UK., Schaer TP; Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, USA., Schwarz EM; Center for Musculoskeletal Research, University of Rochester, Rochester, New York, USA., Spiegel C; Research Laboratory for Biofilms and Implant Associated Infections (BIOFILM LAB), Experimental Orthopedics, University Hospital for Orthopedics and Traumatology, Medical University of Innsbruck, Innsbruck, Austria., Stoodley P; Department Microbial Infection and Immunity and Department of Orthopaedics, The Ohio State University, Columbus, Ohio, USA., Truong VK; Biomedical Nanoengineering Laboratory, College of Medicine and Public Health, Bedford Park, South Australia, Australia., Tsang SJ; Department of Trauma and Orthopaedic Surgery, University of Edinburgh, Edinburgh, Scotland, UK., Wildemann B; Experimental Trauma Surgery, Department of Trauma, Hand and Reconstructive Surgery, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany., Zelmer AR; Centre for Orthopaedic and Trauma Research, University of Adelaide, Adelaide, South Australia, Australia., Zinkernagel AS; Department of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich and University of Zurich, Zurich, Switzerland.

Publikováno v: Journal of orthopaedic research : official publication of the Orthopaedic Research Society [J Orthop Res] 2024 Mar; Vol. 42 (3), pp. 512-517. Date of Electronic Publication: 2024 Jan 12.

Halicin Is Effective Against Staphylococcus aureus Biofilms In Vitro.

Autor: Higashihira S; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Orthopaedic Surgery, Yokohama City University, Yokohama, Japan.; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, USA., Simpson SJ; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA., Collier CD; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA., Natoli RM; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA., Kittaka M; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, USA., Greenfield EM; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA.

Publikováno v: Clinical orthopaedics and related research [Clin Orthop Relat Res] 2022 Aug 01; Vol. 480 (8), pp. 1476-1487. Date of Electronic Publication: 2022 May 17.

Staphylococcus aureus and Acinetobacter baumannii Inhibit Osseointegration of Orthopedic Implants.

Autor: Choe H; Department of Orthopaedics, Case Western Reserve Universitygrid.67105.35, Cleveland, Ohio, USA.; Department of Orthopaedics, Yokohama City University, Yokohama, Kanagawa, Japan., Tatro JM; Department of Orthopaedics, Case Western Reserve Universitygrid.67105.35, Cleveland, Ohio, USA., Hausman BS; Department of Orthopaedics, Case Western Reserve Universitygrid.67105.35, Cleveland, Ohio, USA., Hujer KM; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA., Marshall SH; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA., Akkus O; Department of Mechanical Engineering, Case Western Reserve University, Cleveland, Ohio, USA., Rather PN; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.; Research Service, Atlanta Veterans Affairs Medical Center, Decatur, Georgia, USA., Lee Z; Department of Radiology, Case Western Reserve University, Cleveland, Ohio, USA., Bonomo RA; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA.; Medical Service and GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Center for Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Greenfield EM; Department of Orthopaedics, Case Western Reserve Universitygrid.67105.35, Cleveland, Ohio, USA.; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Publikováno v: Infection and immunity [Infect Immun] 2022 Mar 17; Vol. 90 (3), pp. e0066921. Date of Electronic Publication: 2022 Jan 31.