Application of newly developed SARS-CoV2 serology test along with real-time PCR for early detection in health care workers and on-time plasma donation

Autor: Hossein Samadi Kafil, Mahsa Hajivalili, Abolfazl Miahipour, Amin Kamrani, Javad Ahmadian Heris, Mohammad Sadegh Soltani-Zangbar, Forough Parhizkar, Ramin Pourakbari, Leili Aghebati-Maleki, Oldouz Shareghi-Oskoue, Leila Roshangar, Homayoon Siahmansouri, Sara Farhang, Farhad Jadidi-Niaragh, Roza Motavalli, Maryam Hosseini, Mehdi Yousefi, Mostafa Haji-Fatahaliha, Ata Mahmoodpoor

Publikováno v: Gene Reports

Background As the daily number of coronavirus infection disease 19 (COVID19) patients increases, the necessity of early diagnosis becomes more obvious. In this respect, we aimed to develop a serological test for specifically detecting anti-SARS-CoV2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d67b475e33561104df31ed13cb62237
https://pubmed.ncbi.nlm.nih.gov/33869895

Magnetic graphene quantum dots facilitate closed-tube one-step detection of SARS-CoV-2 with ultra-low field NMR relaxometry

Autor: Hui Dong, Hans-Joachim Krause, Siwei Yang, Peixiang Ma, Yongqiang Li, Guqiao Ding, Xiaoming Xie, Quan Tao

Publikováno v: Sensors and Actuators. B, Chemical
Sensors and actuators / B 337, 129786-(2021). doi:10.1016/j.snb.2021.129786

Graphical abstract
The rapid and sensitive diagnosis of the highly contagious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the crucial issues at the outbreak of the ongoing global pandemic that has no valid cure. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a504f8af2c1607fa881404612c4f6503
http://europepmc.org/articles/PMC7959688

Discovery of the Anti-Angiogenesis Effect of Eltrombopag in Breast Cancer Through Targeting of HuR Protein

Autor: Qianfei Cui, Jiazhen Xu, Pei Zhang, Xiyan Yang, Yuying Zhu, Pengwei Luan, Lixian Jiang, Xinyue Ding, Liuqing Yang, Jiange Zhang, Feiyun Wang, Guoqiang Lin, Ruixiang Li

Publikováno v: Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1414-1425 (2020)
Acta Pharmaceutica Sinica. B

HuR (human antigen R), an mRNA-binding protein responsible for poor prognosis in nearly all kinds of malignancies, is a potential anti-tumor target for drug development. While screening HuR inhibitors with a fluorescence polarization (FP) based high-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b88b56b50bf430ed01e23273ce9d42
https://doi.org/10.2139/ssrn.3424182

Magnetic graphene quantum dots facilitate closed-tube one-step detection of SARS-CoV-2 with ultra-low field NMR relaxometry.

Autor: Li Y; State Key Laboratory of Functional Materials of Informatics, Shanghai Institute of Microsystem and Information Technology (SIMIT), Chinese Academy of Sciences, Shanghai, 200050, PR China.; CAS Center for ExcelleNce in Superconducting Electronics (CENSE), Chinese Academy of Sciences, Shanghai, 200050, PR China.; Joint Research Institute on Functional Materials and Electronics, Collaboration between SIMIT and FZJ, Germany.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, 100049, PR China., Ma P; Shanghai Institute for Advanced Immunological Studies, ShanghaiTech University, Shanghai, 201210, PR China., Tao Q; State Key Laboratory of Functional Materials of Informatics, Shanghai Institute of Microsystem and Information Technology (SIMIT), Chinese Academy of Sciences, Shanghai, 200050, PR China.; CAS Center for ExcelleNce in Superconducting Electronics (CENSE), Chinese Academy of Sciences, Shanghai, 200050, PR China.; Joint Research Institute on Functional Materials and Electronics, Collaboration between SIMIT and FZJ, Germany.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, 100049, PR China., Krause HJ; Institute of Biological Information Processing (IBI-3), Forschungszentrum Jülich (FZJ), D-52425, Jülich, Germany.; Joint Research Institute on Functional Materials and Electronics, Collaboration between SIMIT and FZJ, Germany., Yang S; State Key Laboratory of Functional Materials of Informatics, Shanghai Institute of Microsystem and Information Technology (SIMIT), Chinese Academy of Sciences, Shanghai, 200050, PR China.; Joint Research Institute on Functional Materials and Electronics, Collaboration between SIMIT and FZJ, Germany.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, 100049, PR China., Ding G; State Key Laboratory of Functional Materials of Informatics, Shanghai Institute of Microsystem and Information Technology (SIMIT), Chinese Academy of Sciences, Shanghai, 200050, PR China.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, 100049, PR China., Dong H; State Key Laboratory of Functional Materials of Informatics, Shanghai Institute of Microsystem and Information Technology (SIMIT), Chinese Academy of Sciences, Shanghai, 200050, PR China.; CAS Center for ExcelleNce in Superconducting Electronics (CENSE), Chinese Academy of Sciences, Shanghai, 200050, PR China.; Joint Research Institute on Functional Materials and Electronics, Collaboration between SIMIT and FZJ, Germany.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, 100049, PR China., Xie X; State Key Laboratory of Functional Materials of Informatics, Shanghai Institute of Microsystem and Information Technology (SIMIT), Chinese Academy of Sciences, Shanghai, 200050, PR China.; CAS Center for ExcelleNce in Superconducting Electronics (CENSE), Chinese Academy of Sciences, Shanghai, 200050, PR China.; Joint Research Institute on Functional Materials and Electronics, Collaboration between SIMIT and FZJ, Germany.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, 100049, PR China.

Publikováno v: Sensors and actuators. B, Chemical [Sens Actuators B Chem] 2021 Jun 15; Vol. 337, pp. 129786. Date of Electronic Publication: 2021 Mar 15.

Discovery of the anti-angiogenesis effect of eltrombopag in breast cancer through targeting of HuR protein.

Autor: Zhu Y; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Yang L; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Xu J; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Yang X; Institute of Drug Discovery and Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Luan P; Institute of Drug Discovery and Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Cui Q; Institute of Drug Discovery and Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Zhang P; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Wang F; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Li R; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Ding X; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Jiang L; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Lin G; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Zhang J; The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Aug; Vol. 10 (8), pp. 1414-1425. Date of Electronic Publication: 2020 Feb 24.