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Autor: Elia, Josephine A., Li, Jie, Floudas, Christodoulos A.

Publikováno v: In Computers and Chemical Engineering 2 January 2015 72:109-125

Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p

Autor: Weiner, Daniel J., Ling, Emi, Erdin, Serkan, Tai, Derek J. C., Yadav, Rachita, Grove, Jakob, Fu, Jack M., Nadig, Ajay, Carey, Caitlin E., Baya, Nikolas, Bybjerg-Grauholm, Jonas, Mortensen, Preben B., Werge, Thomas, Demontis, Ditte, Mors, Ole, Nordentoft, Merete, Als, Thomas D., Baekvad-Hansen, Marie, Rosengren, Anders, Havdahl, Alexandra, Hedemand, Anne, Palotie, Aarno, Chakravarti, Aravinda, Arking, Dan, Sulovari, Arvis, Starnawska, Anna, Thiruvahindrapuram, Bhooma, de Leeuw, Christiaan, Carey, Caitlin, Ladd-Acosta, Christine, van der Merwe, Celia, Devlin, Bernie, Cook, Edwin H., Eichler, Evan, Corfield, Elisabeth, Dieleman, Gwen, Schellenberg, Gerard, Hakonarson, Hakon, Coon, Hilary, Dziobek, Isabel, Vorstman, Jacob, Girault, Jessica, Sutcliffe, James S., Duan, Jinjie, Nurnberger, John, Hallmayer, Joachim, Buxbaum, Joseph, Piven, Joseph, Weiss, Lauren, Davis, Lea, Janecka, Magdalena, Mattheisen, Manuel, State, Matthew W., Gill, Michael, Daly, Mark, Uddin, Mohammed, Andreassen, Ole, Szatmari, Peter, Lee, Phil Hyoun, Anney, Richard, Ripke, Stephan, Satterstrom, Kyle, Santangelo, Susan, Kuo, Susan, van Elst, Ludger Tebartz, Rolland, Thomas, Bougeron, Thomas, Polderman, Tinca, Turner, Tychele, Underwood, Jack, Manikandan, Veera, Pillalamarri, Vamsee, Warrier, Varun, Philipsen, Alexandra, Reif, Andreas, Hinney, Anke, Cormand, Bru, Bau, Claiton H. D., Rovaris, Diego Luiz, Sonuga-Barke, Edmund, Corfield, Elizabeth, Grevet, Eugenio Horacio, Salum, Giovanni, Larsson, Henrik, Buitelaar, Jan, Haavik, Jan, McGough, James, Kuntsi, Jonna, Elia, Josephine, Lesch, Klaus-Peter, Klein, Marieke, Bellgrove, Mark, Tesli, Martin, Leung, Patrick W. L., Pan, Pedro M., Dalsgaard, Soren, Loo, Sandra, Medland, Sarah, Faraone, Stephen V., Reichborn-Kjennerud, Ted, Banaschewski, Tobias, Hawi, Ziarih, Berretta, Sabina, Macosko, Evan Z., Sebat, Jonathan, O’Connor, Luke J., Hougaard, David M., Børglum, Anders D., Talkowski, Michael E., McCarroll, Steven A., Robinson, Elise B.

Publikováno v: Nature Genetics, 54(11), 1630-1639. Nature Publishing Group
Nature Genetics
Weiner, D J, Ling, E, Erdin, S, Tai, D J C, Yadav, R, Grove, J, Fu, J M, Nadig, A, Carey, C E, Baya, N, Bybjerg-Grauholm, J, Mortensen, P B, Werge, T, Demontis, D, Mors, O, Nordentoft, M, Als, T D, Baekvad-Hansen, M, Rosengren, A, Havdahl, A, Hedemand, A, Palotie, A, Chakravarti, A, Arking, D, Sulovari, A, Starnawska, A, Thiruvahindrapuram, B, de Leeuw, C, Carey, C, Ladd-Acosta, C, van der Merwe, C, Devlin, B, Cook, E H, Eichler, E, Corfield, E, Dieleman, G, Schellenberg, G, Hakonarson, H, Coon, H, Dziobek, I, Vorstman, J, Girault, J, Sutcliffe, J S, Duan, J, Nurnberger, J, Hallmayer, J, Buxbaum, J, Piven, J, Weiss, L, Davis, L, Janecka, M, Mattheisen, M, State, M W, Gill, M, Daly, M, Uddin, M, Andreassen, O, Szatmari, P, Lee, P H, Anney, R, Ripke, S, Satterstrom, K, Santangelo, S, Kuo, S, van Elst, L T, Rolland, T, Bougeron, T, Polderman, T, Turner, T, Underwood, J, Manikandan, V, Pillalamarri, V, Warrier, V, Philipsen, A, Reif, A, Hinney, A, Cormand, B, Bau, C H D, Rovaris, D L, Sonuga-Barke, E, Corfield, E, Grevet, E H, Salum, G, Larsson, H, Buitelaar, J, Haavik, J, McGough, J, Kuntsi, J, Elia, J, Lesch, K-P, Klein, M, Bellgrove, M, Tesli, M, Leung, P W L, Pan, P M, Dalsgaard, S, Loo, S, Medland, S, iPSYCH Consortium, Faraone, S V, ASD Working Group of the Psychiatric Genomics Consortium, Reichborn-Kjennerud, T, ADHD Working Group of the Psychiatric Genomics Consortium, Banaschewski, T, Hawi, Z, Berretta, S, Macosko, E Z, Sebat, J, O’Connor, L J, Hougaard, D M, Børglum, A D, Talkowski, M E, McCarroll, S A & Robinson, E B 2022, ' Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p ', Nature Genetics, vol. 54, no. 11, pp. 1630-1639 . https://doi.org/10.1038/s41588-022-01203-y
Weiner, D J, Ling, E, Erdin, S, Tai, D J C, Yadav, R, Grove, J, Fu, J M, Nadig, A, Carey, C, Baya, N, Bybjerg-Grauholm, J, Mortensen, P B, Werge, T, Demontis, D, Mors, O, Nordentoft, M, Als, T D, Baekvad-Hansen, M, Rosengren, A, Havdahl, A, Hedemand, A, Palotie, A, Chakravarti, A, Arking, D, Sulovari, A, Starnawska, A, Thiruvahindrapuram, B, de Leeuw, C, Carey, C, Ladd-Acosta, C, van der Merwe, C, Devlin, B, Cook, E H, Eichler, E, Corfield, E, Dieleman, G, Schellenberg, G, Hakonarson, H, Coon, H, Dziobek, I, Vorstman, J, Girault, J, Sutcliffe, J S, Duan, J, Nurnberger, J, Hallmayer, J, Buxbaum, J, Hinney, A, Larsson, H, Dalsgaard, S, iPSYCH Consortium, ASD Working Group of the Psychiatric Genomics Consortium & ADHD Working Group of the Psychiatric Genomics Consortium 2022, ' Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p ', Nature Genetics, vol. 54, pp. 1630-1639 . https://doi.org/10.1038/s41588-022-01203-y
Weiner, D J, Ling, E, Erdin, S, Tai, D J C, Yadav, R, Grove, J, Fu, J M, Nadig, A, Carey, C E, Baya, N, Bybjerg-Grauholm, J, iPSYCH Consortium, ASD Working Group of the Psychiatric Genomics Consortium, ADHD Working Group of the Psychiatric Genomics Consortium, Berretta, S, Macosko, E Z, Sebat, J, O'Connor, L J, Hougaard, D M, Børglum, A D, Talkowski, M E, McCarroll, S A & Robinson, E B 2022, ' Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p ', Nature Genetics, vol. 54, no. 11, pp. 1630-1639 . https://doi.org/10.1038/s41588-022-01203-y
iPSYCH Consortium, ASD Working Group of the Psychiatric Genomics Consortium & ADHD Working Group of the Psychiatric Genomics Consortium 2022, ' Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p ', Nature genetics, vol. 54, no. 11, pp. 1630-1639 . https://doi.org/10.1038/s41588-022-01203-y
Nature genetics, 54(11), 1630-1639. Nature Publishing Group

in press, weitere Verfasser:innen aus Einrichtungen außerhalb der Universität Duisburg-Essen sind nicht aufgeführt. The canonical paradigm for converting genetic association to mechanism involves iteratively mapping individual associations to the

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