Zobrazeno 1 - 10
of 68
pro vyhledávání: '"ELENA TIRRÒ"'
Autor:
Maria Stella Pennisi, Sandra Di Gregorio, Elena Tirrò, Chiara Romano, Andrea Duminuco, Bruno Garibaldi, Gaetano Giuffrida, Livia Manzella, Paolo Vigneri, Giuseppe A. Palumbo
Publikováno v:
Hematology Reports, Vol 15, Iss 2, Pp 317-324 (2023)
Essential thrombocythemia (ET) and primary myelofibrosis (PMF) are two of the main BCR-ABL1-negative chronic myeloproliferative neoplasms (MPNs) characterized by abnormal megakaryocytic proliferation. Janus kinase 2 (JAK2) mutations are detected in 5
Externí odkaz:
https://doaj.org/article/0f2895a965554aea8fd58e369039bcf1
Autor:
Veronica Veschi, Alice Turdo, Chiara Modica, Francesco Verona, Simone Di Franco, Miriam Gaggianesi, Elena Tirrò, Sebastiano Di Bella, Melania Lo Iacono, Vincenzo Davide Pantina, Gaetana Porcelli, Laura Rosa Mangiapane, Paola Bianca, Aroldo Rizzo, Elisabetta Sciacca, Irene Pillitteri, Veronica Vella, Antonino Belfiore, Maria Rita Bongiorno, Giuseppe Pistone, Lorenzo Memeo, Lorenzo Colarossi, Dario Giuffrida, Cristina Colarossi, Paolo Vigneri, Matilde Todaro, Giorgio Stassi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Thyroid carcinoma (TC) is the most common malignancy of endocrine organs. Here, the authors show the ability of human embryonic stem cells (hESCs) to recapitulate the different TC histotypes upon specific genomic alterations delivered by CRISPR-Cas9
Externí odkaz:
https://doaj.org/article/ebd761e297f5412baf73304e9e1e2d72
Autor:
Elena Tirrò, Michele Massimino, Giuseppe Broggi, Chiara Romano, Simone Minasi, Francesca Gianno, Manila Antonelli, Gianmarco Motta, Francesco Certo, Roberto Altieri, Livia Manzella, Rosario Caltabiano, Giuseppe Maria Vincenzo Barbagallo, Francesca Romana Buttarelli, Gaetano Magro, Felice Giangaspero, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The management of patients with Central Nervous System (CNS) malignancies relies on the appropriate classification of these tumors. Recently, the World Health Organization (WHO) has published new criteria underlining the importance of an accurate mol
Externí odkaz:
https://doaj.org/article/8b4a7086a7bf44bdb5b01f6967f63c5b
Autor:
Giuseppe Broggi, Eliana Piombino, Roberto Altieri, Chiara Romano, Francesco Certo, Giuseppe Maria Vincenzo Barbagallo, Paolo Vigneri, Dario Condorelli, Lorenzo Colarossi, Cristina Colarossi, Gaetano Magro, Elena Tirrò
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
It has been reported that in-frame FGFR3-TACC3 fusions confer to glioblastomas, IDH-wild type (GBMs, IDHwt) some unusual morphologic features, including monomorphous rounded cells with ovoid nuclei, nuclear palisading, endocrinoid network of “chick
Externí odkaz:
https://doaj.org/article/c0a7164a67e646acb44ed099c30a2b71
Autor:
Michele Massimino, Elena Tirrò, Stefania Stella, Livia Manzella, Maria Stella Pennisi, Chiara Romano, Silvia Rita Vitale, Adriana Puma, Cristina Tomarchio, Sandra Di Gregorio, Agostino Antolino, Francesco Di Raimondo, Paolo Vigneri
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Chronic Myeloid Leukemia (CML) is a hematological disorder characterized by the clonal expansion of a hematopoietic stem cell carrying the Philadelphia chromosome that juxtaposes the BCR and ABL1 genes. The ensuing BCR-ABL1 chimeric oncogene is chara
Externí odkaz:
https://doaj.org/article/e64984d411ed458d9ee29e056ad88a5f
Autor:
Elena Tirrò, Michele Massimino, Chiara Romano, Federica Martorana, Maria Stella Pennisi, Stefania Stella, Giuliana Pavone, Sandra Di Gregorio, Adriana Puma, Cristina Tomarchio, Silvia Rita Vitale, Livia Manzella, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Glioblastoma multiforme (GBM) is the most common primary brain malignancy and is often resistant to conventional treatments due to its extensive cellular heterogeneity. Thus, the overall survival of GBM patients remains extremely poor. Insulin-like g
Externí odkaz:
https://doaj.org/article/5b3b2a650bd34cddbfe18451893beb66
Autor:
Stefania Stella, Silvia Rita Vitale, Fabio Stagno, Michele Massimino, Adriana Puma, Cristina Tomarchio, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Francesco Di Raimondo, Emma Cacciola, Rossella Cacciola, Livia Manzella
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1051 (2022)
Background: Detection of BCR-ABL1 transcript level via real-time quantitative-polymerase-chain reaction (Q-PCR) is a clinical routine for disease monitoring, assessing Tyrosine Kinase Inhibitor therapy efficacy and predicting long-term response in ch
Externí odkaz:
https://doaj.org/article/f7d7cb5661ca4f51a9017dfe1bdc1026
Autor:
Maria Failla, Rosario Caltabiano, Antonio Longo, Andrea Russo, Michele Reibaldi, Teresio Avitabile, Eliana Piombino, Cristina Colarossi, Lorenzo Colarossi, Elena Tirrò, Paolo Vigneri, Pietro Valerio Foti, Giuseppe Broggi
Publikováno v:
Diagnostics, Vol 12, Iss 3, p 642 (2022)
Uveal melanoma (UM) is the most common primary intraocular tumor in adults and usually has a very poor prognosis. Histologically, UMs have been classified in epithelioid cell type, spindle cell type, and mixed cell type. Balloon cells are large pale
Externí odkaz:
https://doaj.org/article/0cd5d529102041eba820d51eb22249d3
Autor:
Michele Massimino, Stefania Stella, Elena Tirrò, Chiara Romano, Maria Stella Pennisi, Adriana Puma, Livia Manzella, Antonino Zanghì, Fabio Stagno, Francesco Di Raimondo, Paolo Vigneri
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract The introduction of ABL Tyrosine Kinase Inhibitors (TKIs) has significantly improved the outcome of Chronic Myeloid Leukemia (CML) patients that, in large part, achieve satisfactory hematological, cytogenetic and molecular remissions. Howeve
Externí odkaz:
https://doaj.org/article/9b21a4b502ea48ec89c59850edc2e6d1
Autor:
Stefania Stella, Silvia Rita Vitale, Michele Massimino, Adriana Puma, Cristina Tomarchio, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Federica Martorana, Fabio Stagno, Francesco Di Raimondo, Livia Manzella
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1502 (2021)
Molecular testing of the BCR-ABL1 transcript via real-time quantitative-polymerase-chain-reaction is the most sensitive approach for monitoring the response to tyrosine-kinase-inhibitors therapy in chronic myeloid leukaemia (CML) patients. Each stage
Externí odkaz:
https://doaj.org/article/605f9d39700947e9b08dab2fb0be37e4