Zobrazeno 1 - 10
of 197
pro vyhledávání: '"ELENA A. KOTOVA"'
Autor:
Roman S. Kirsanov, Ljudmila S. Khailova, Tatyana I. Rokitskaya, Konstantin G. Lyamzaev, Alisa A. Panteleeva, Pavel A. Nazarov, Alexander M. Firsov, Iliuza R. Iaubasarova, Galina A. Korshunova, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
ACS Omega, Vol 9, Iss 10, Pp 11551-11561 (2024)
Externí odkaz:
https://doaj.org/article/a4be645a79fa4de490a45a3780dca471
Autor:
Pavel A. Nazarov, Vladislav S. Maximov, Alexander M. Firsov, Marina V. Karakozova, Veronika Panfilova, Elena A. Kotova, Maxim V. Skulachev, Yuri N. Antonenko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6137 (2024)
Mitochondria-targeted antioxidants (MTAs) have been studied quite intensively in recent years as potential therapeutic agents and vectors for the delivery of other active substances to mitochondria and bacteria. Their most studied representatives are
Externí odkaz:
https://doaj.org/article/60d327de2eb64c31baf99c99657766e1
Autor:
Natalia V. Terekhova, Lyudmila S. Khailova, Tatyana I. Rokitskaya, Pavel A. Nazarov, Daut R. Islamov, Konstantin S. Usachev, Dmitry A. Tatarinov, Vladimir F. Mironov, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
ACS Omega, Vol 6, Iss 31, Pp 20676-20685 (2021)
Externí odkaz:
https://doaj.org/article/a093cf395faf4ab4a4c28b3669d71c02
Autor:
Tatyana I. Rokitskaya, Alexander M. Arutyunyan, Ljudmila S. Khailova, Alisa D. Kataeva, Alexander M. Firsov, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16203 (2022)
Usnic acid (UA), a unique lichen metabolite, is a protonophoric uncoupler of oxidative phosphorylation, widely known as a weight-loss dietary supplement. In contrast to conventional proton-shuttling mitochondrial uncouplers, UA was found to carry pro
Externí odkaz:
https://doaj.org/article/f5947b57755e45d495a0d0a1646a4dce
Autor:
Rita V. Chertkova, Alexander M. Firsov, Nadezda A. Brazhe, Evelina I. Nikelshparg, Zhanna V. Bochkova, Tatyana V. Bryantseva, Marina A. Semenova, Adil A. Baizhumanov, Elena A. Kotova, Mikhail P. Kirpichnikov, Georgy V. Maksimov, Yuriy N. Antonenko, Dmitry A. Dolgikh
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 665 (2022)
A key event in the cytochrome c-dependent apoptotic pathway is the permeabilization of the outer mitochondrial membrane, resulting in the release of various apoptogenic factors, including cytochrome c, into the cytosol. It is believed that the permea
Externí odkaz:
https://doaj.org/article/c9c20935cd1246f7b0ef1028804b5386
Autor:
Kristina Žuna, Olga Jovanović, Ljudmila S. Khailova, Sanja Škulj, Zlatko Brkljača, Jürgen Kreiter, Elena A. Kotova, Mario Vazdar, Yuri N. Antonenko, Elena E. Pohl
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1178 (2021)
2,4-Dinitrophenol (DNP) is a classic uncoupler of oxidative phosphorylation in mitochondria which is still used in “diet pills”, despite its high toxicity and lack of antidotes. DNP increases the proton current through pure lipid membranes, simil
Externí odkaz:
https://doaj.org/article/4fb6fca490fe43ebb70f5c9001e33479
Autor:
Pavel A. Nazarov, Ilya A. Osterman, Artem V. Tokarchuk, Marina V. Karakozova, Galina A. Korshunova, Konstantin G. Lyamzaev, Maxim V. Skulachev, Elena A. Kotova, Vladimir P. Skulachev, Yuri N. Antonenko
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mitochondria-targeted antioxidants are known to alleviate mitochondrial oxidative damage that is associated with a variety of diseases. Here, we showed that SkQ1, a decyltriphenyl phosphonium cation conjugated to a quinone moiety, exhibited
Externí odkaz:
https://doaj.org/article/15da0121ba4a44c098f410443074d542
Autor:
Pavel A. Nazarov, Roman S. Kirsanov, Stepan S. Denisov, Ljudmila S. Khailova, Marina V. Karakozova, Konstantin G. Lyamzaev, Galina A. Korshunova, Konstantin A. Lukyanov, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 309 (2020)
Appending a lipophylic alkyl chain by ester bond to fluorescein has been previously shown to convert this popular dye into an effective protonophoric uncoupler of oxidative phosphorylation in mitochondria, exhibiting neuro- and nephroprotective effec
Externí odkaz:
https://doaj.org/article/4b11e352d7ed4190a4089a20701f1c43
Publikováno v:
Antioxidants, Vol 8, Iss 6, p 194 (2019)
It is generally considered that reactive oxygen species (ROS) are involved in the development of numerous pathologies. The level of ROS can be altered via the uncoupling of oxidative phosphorylation by using protonophores causing mitochondrial membra
Externí odkaz:
https://doaj.org/article/2118f00f330449d6ab143d9b863e19db
Autor:
Han-Wen Chang, Alexey V. Feofanov, Alexander V. Lyubitelev, Grigory A. Armeev, Elena Y. Kotova, Fu-Kai Hsieh, Mikhail P. Kirpichnikov, Alexey K. Shaytan, Vasily M. Studitsky
Publikováno v:
Cells, Vol 11, Iss 16, p 2475 (2022)
Histone N-terminal tails and their post-translational modifications affect various biological processes, often in a context-specific manner; the underlying mechanisms are poorly studied. Here, the role of individual N-terminal tails of histones H2A/H
Externí odkaz:
https://doaj.org/article/93606d7b46b7459aa3494a6bed92aa5b