Zobrazeno 1 - 10 of 59 pro vyhledávání: '"EKE G. GRUPPEN"'
1
Akademický článek
Novel Size‐Based High‐Density Lipoprotein Subspecies and Incident Vascular Events
Autor: Austin Deets, Parag H. Joshi, Alvin Chandra, Kavisha Singh, Amit Khera, Salim S. Virani, Christie M. Ballantyne, James D. Otvos, Robin P. F. Dullaart, Eke G. Gruppen, Margery A. Connelly, Colby Ayers, Ann Marie Navar, Ambarish Pandey, John T. Wilkins, Anand Rohatgi
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background High‐density lipoprotein (HDL) particle concentration likely outperforms HDL cholesterol in predicting atherosclerotic cardiovascular events. Whether size‐based HDL subspecies explain the atheroprotective associations of HDL particle c
Externí odkaz: https://doaj.org/article/3ef89734bb2f46c88e6ec6de3a77d86f
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2
Akademický článek
Serum paraoxonase 1 activity is paradoxically maintained in nonalcoholic fatty liver disease despite low HDL cholesterol[S]
Autor: Eline H. van den Berg, Eke G. Gruppen, Richard W. James, Stephan J.L. Bakker, Robin P.F. Dullaart
Publikováno v: Journal of Lipid Research, Vol 60, Iss 1, Pp 168-175 (2019)
Nonalcoholic fatty liver disease (NAFLD) is characterized by low HDL cholesterol, but the activity of the HDL-associated antioxidative enzyme paraoxonase-1 (PON-1) remains unclear. To determine the association of PON-1 with suspected NAFLD, we measur
Externí odkaz: https://doaj.org/article/738d73e2f25142d593d44f20e9fa171d
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3
Akademický článek
Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation
Autor: Eke G. Gruppen, Sander Kersten, Robin P. F. Dullaart
Publikováno v: Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background Angiopoietin-like 4 (ANGPTL4) inhibits lipoprotein lipase, whereas phospholipid transfer protein (PLTP) enhances hepatic triglyceride secretion. Both factors may be upregulated by inflammatory pathways. Since the extent to which t
Externí odkaz: https://doaj.org/article/a7f7a18fb3d041099c289261192e6ced
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4
Akademický článek
The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation
Autor: Sanam Ebtehaj, Eke G. Gruppen, Mojtaba Parvizi, Uwe J. F. Tietge, Robin P. F. Dullaart
Publikováno v: Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background Functional properties of high density lipoproteins (HDL) are increasingly recognized to play a physiological role in atheroprotection. Type 2 diabetes mellitus (T2DM) is characterized by low HDL cholesterol, but the effect of chro
Externí odkaz: https://doaj.org/article/fa3a5f17b79242b681ef73a355c4cf4a
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5
Urinary albumin excretion and cancer risk: the PREVEND cohort study
Autor: Li Luo, Lyanne M Kieneker, Bert van der Vegt, Stephan J L Bakker, Eke G Gruppen, Niek F Casteleijn, Rudolf A de Boer, Navin Suthahar, Geertruida H de Bock, Joseph Pierre Aboumsallem, Priya Vart, Ron T Gansevoort
Publikováno v: Nephrology Dialysis Transplantation.
Background Chronic kidney disease (CKD) is believed to be associated with an increased risk for cancer, especially urinary tract cancer. However, previous studies predominantly focussed on the association of decreased estimated glomerular filtration
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b41eb218aabf60503dc9e8268e755357
https://doi.org/10.1093/ndt/gfad107
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6
Plasma levels of GlycA, a pro-inflammatory glycoprotein biomarker, associate with an increased risk of microvascular complications in patients with type 2 diabetes (Zodiac-62)
Autor: Arno R. Bourgonje, Amarens van der Vaart, Eke G. Gruppen, Harry van Goor, Stephan J. L. Bakker, Margery A. Connelly, Peter R. van Dijk, Robin P. F. Dullaart
Publikováno v: Endocrine. SPRINGER
PurposeGlycA, a pro-inflammatory glycoprotein biomarker, associates with newly developed type 2 diabetes (T2D). We determined the association of plasma GlycA with the development of microvascular complications in patients with established T2D.Methods
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577f51986a096a74aa1c38d3039f7f3e
https://doi.org/10.1007/s12020-023-03319-5
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7
Nonalcoholic fatty liver disease, circulating ketone bodies and all-cause mortality in a general population-based cohort
Autor: Robin P. F. Dullaart, Margery A. Connelly, Stephan J. L. Bakker, B. D. Westenbrink, Dion Groothof, Adrian Post, Jose L. Flores-Guerrero, Eke G. Gruppen, Erwin Garcia, Eline H. van den Berg
Publikováno v: European Journal of Clinical Investigation, 51(12):13627, 1-12. Wiley
Background Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent, paralleling the obesity epidemic. Ketone bodies are produced in the liver, but it is currently uncertain whether circulating ketone bodies are increased in the context of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96494e2996c0793295e4355c9d4832e0
https://research.rug.nl/en/publications/e7301b4a-3a85-4372-bbec-4ad59a6bc6b9
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8
High-Density Lipoprotein Anti-Inflammatory Capacity and Incident Cardiovascular Events
Autor: Uwe J. F. Tietge, Stephan J. L. Bakker, Robin P. F. Dullaart, Eke G. Gruppen, Josephine L. C. Anderson, Congzhuo Jia, Yu Lei
Publikováno v: Circulation, 143(20), 1935-1945. LIPPINCOTT WILLIAMS & WILKINS
Circulation
Background: The role of high-density lipoprotein (HDL) function in cardiovascular disease represents an important emerging concept. The present study investigated whether HDL anti-inflammatory capacity is prospectively associated with first cardiovas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280f5b0fbabc144951783da23663aeba
https://doi.org/10.1161/circulationaha.120.050808
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9
Adiposity and the development of dyslipidemia in APOE epsilon 2 homozygous subjects
Autor: Britt E. Heidemann, Charlotte Koopal, Frank J. Wolters, Eke G. Gruppen, Frank L.J. Visseren, Maryam Kavousi, A. David Marais, Robin P. F. Dullaart
Publikováno v: Atherosclerosis, 325, 57-62. Elsevier Ireland Ltd
ATHEROSCLEROSIS, 325, 57-62. ELSEVIER IRELAND LTD
Background and aims: Familial dysbetalipoproteinemia (FD), characterized by remnant lipoprotein accumulation and premature cardiovascular disease, occurs in homozygous carriers of the APOE epsilon 2 allele, but genetic predisposition alone does not s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240cb741ddab9e1c4ad5a038682acf49
https://research.rug.nl/en/publications/24c45f5e-2f9b-4a37-b48b-8f70223706fb
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10
Thyroid function and risk of all-cause and cardiovascular mortality
Autor: Stephan J. L. Bakker, Dion Groothof, Martin H. de Borst, Reinold O. B. Gans, Hjalmar R. Bouma, Arjola Bano, Jose L. Flores-Guerrero, Jenny E. Kootstra-Ros, Eke G. Gruppen, Jens H. J. Bos, Ilja M. Nolte, Eelko Hak, Adrian Post, Robin P. F. Dullaart, Thera P. Links
Publikováno v: Groothof, Dion; Flores-Guerrero, Jose L; Nolte, Ilja M; Bouma, Hjalmar R; Gruppen, Eke G; Bano, Arjola; Post, Adrian; Kootstra-Ros, Jenny E; Hak, Eelko; Bos, Jens H J; de Borst, Martin H; Gans, Reinold O B; Links, Thera P; Dullaart, Robin P F; Bakker, Stephan J L (2021). Thyroid function and risk of all-cause and cardiovascular mortality: a prospective population-based cohort study. Endocrine, 71(2), pp. 385-396. Springer (part of Springer Nature): Springer Open Choice Hybrid Journals 10.1007/s12020-020-02397-z
Endocrine, 71(2), 385-396. SPRINGER
Endocrine
Purpose Although thyroid hormones are irrefutably implicated in cardiovascular physiology, the impact of within-reference range variations of thyroid function on cardiovascular disease (CVD) remains unclear. Elucidating this is important, since it co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9fa4877589ec7fb2e3baca0624022d
https://research.rug.nl/en/publications/eb41cfd0-49be-47f9-9249-16ef3f012f0d
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