Epigenetic modifiers direct lineage switch in MLL-AF4 leukemia

Autor: K Szoltysek, R Tirtakusuma, M Ashtiani, S Nakjang, V V Grinev, J Hehir-Kwa, EK Schweighart, S Bomken, O Heidenreich

Publikováno v: Klinische Pädiatrie.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c63e65b196c4fb50289f9835911dca34
https://doi.org/10.1055/s-0042-1748750

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.

Autor: Tirtakusuma R; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Szoltysek K; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Maria Sklodowska-Curie Institute, Oncology Center, Gliwice Branch, Gliwice, Poland., Milne P; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Grinev VV; Department of Genetics, the Faculty of Biology, Belarusian State University, Minsk, Republic of Belarus., Ptasinska A; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Chin PS; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Meyer C; Institute of Pharmaceutical Biology/DCAL, Goethe-University, Frankfurt/Main, Germany., Nakjang S; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Hehir-Kwa JY; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., Williamson D; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Cauchy P; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Keane P; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Assi SA; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Ashtiani M; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., Kellaway SG; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Imperato MR; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Vogiatzi F; ALL-BFM Study Group, Pediatric Hematology/Oncology, Christian Albrechts University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, Germany., Schweighart EK; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., Lin S; Experimental Hematology and Cancer Biology, Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Wunderlich M; Experimental Hematology and Cancer Biology, Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Stutterheim J; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., Komkov A; Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, Moscow, Russia., Zerkalenkova E; Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, Moscow, Russia., Evans P; Haematological Malignancy Diagnostic Service, St James's University Hospital, Leeds, United Kingdom., McNeill H; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Elder A; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Martinez-Soria N; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Fordham SE; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Shi Y; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Russell LJ; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Pal D; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Smith A; Epidemiology and Cancer Statistics Group, University of York, York, United Kingdom., Kingsbury Z; Illumina Cambridge Ltd., Great Abington, United Kingdom., Becq J; Illumina Cambridge Ltd., Great Abington, United Kingdom., Eckert C; Department of Pediatric Oncology/Hematology, Charité Universitätsmedizin Berlin, Berlin, Germany., Haas OA; St Anna Children's Cancer Research Institute (CCRI), Vienna, Austria., Carey P; Department of Paediatric Haematology and Oncology, The Great North Children's Hospital, Newcastle upon Tyne, United Kingdom., Bailey S; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Department of Paediatric Haematology and Oncology, The Great North Children's Hospital, Newcastle upon Tyne, United Kingdom., Skinner R; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Department of Paediatric Haematology and Oncology, The Great North Children's Hospital, Newcastle upon Tyne, United Kingdom., Miakova N; Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, Moscow, Russia., Collin M; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Bigley V; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Haniffa M; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.; Department of Dermatology and Newcastle National Institute of Health Research (NIHR), Newcastle Biomedical Research Centre, Newcastle Hospitals National Health Service (NHS) Foundation Trust, Newcastle upon Tyne, United Kingdom., Marschalek R; Institute of Pharmaceutical Biology/DCAL, Goethe-University, Frankfurt/Main, Germany., Harrison CJ; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Cargo CA; Haematological Malignancy Diagnostic Service, St James's University Hospital, Leeds, United Kingdom., Schewe D; Department of Pediatrics, Otto von Guericke University Magdeburg, Magdeburg, Germany., Olshanskaya Y; Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, Moscow, Russia., Thirman MJ; Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL., Cockerill PN; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Mulloy JC; Experimental Hematology and Cancer Biology, Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Blair HJ; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Vormoor J; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., Allan JM; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Bonifer C; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Heidenreich O; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., Bomken S; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Department of Paediatric Haematology and Oncology, The Great North Children's Hospital, Newcastle upon Tyne, United Kingdom.

Publikováno v: Blood [Blood] 2022 Oct 27; Vol. 140 (17), pp. 1875-1890.