Zobrazeno 1 - 10
of 100
pro vyhledávání: '"EK Novak"'
Autor:
William C. Nichols, RT Swank, JD Ballew, KA Cooney, K. L. Mohlke, M Reddington, EK Novak, ME Bruck, A Yang, David Ginsburg
Publikováno v:
Blood. 83:3225-3231
An animal model for human type I von Willebrand disease (vWD) has been previously described in the inbred mouse strain RIIIS/J. Murine vWD is characterized by a prolonged bleeding time, normal von Willebrand factor (vWF) multimer distribution, autoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1128cda6d32c677a56b0355e6da6cb73
https://doi.org/10.1182/blood.v83.11.3225.3225
https://doi.org/10.1182/blood.v83.11.3225.3225
Publikováno v:
Blood. 81:2626-2635
Gunmetal (gm/gm) is a recessively inherited mouse pigment dilution mutant that has high mortality and poor reproductive rates. In these studies, several hematologic defects were found associated with the mutation, including prolonged bleeding times,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20973cca029edf63981e552c7b24b162
https://doi.org/10.1182/blood.v81.10.2626.bloodjournal81102626
https://doi.org/10.1182/blood.v81.10.2626.bloodjournal81102626
Publikováno v:
Blood. 78:2036-2044
Several inherited human syndromes have combined platelet, auditory, and/or pigment abnormalities. In the mouse the pallid pigment mutant has abnormalities of the otoliths of the inner ear together with a bleeding abnormality caused by platelet storag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b70a391a433a3bb41b006fb77ba43b
https://doi.org/10.1182/blood.v78.8.2036.bloodjournal7882036
https://doi.org/10.1182/blood.v78.8.2036.bloodjournal7882036
Autor:
Zhen L, Jiang S, Feng L, Na, Bright, Andrew Peden, Ab, Seymour, Ek, Novak, Elliott R, Mb, Gorin, Ms, Robinson, Rt, Swank
Publikováno v:
Europe PubMed Central
The pearl mouse is a model for Hermansky Pudlak Syndrome (HPS), whose symptoms include hypopigmentation, lysosomal abnormalities, and prolonged bleeding due to platelet storage pool deficiency (SPD). The gene for pearl has recently been identified as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::120240d1a6cbb3115498d0b4ee0f0a8b
https://pubmed.ncbi.nlm.nih.gov/10381507
https://pubmed.ncbi.nlm.nih.gov/10381507
Publikováno v:
Blood. 76(11)
Mice of the RIIIS/J inbred strain have prolonged bleeding times (greater than 15 minutes) after experimental injury when compared with normal C57BL/6J mice (1.8 minutes) and other strains of mice. The prolonged bleeding time was accompanied by normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de78f497e3d75e7067fdf5516235ac4
https://pubmed.ncbi.nlm.nih.gov/2124152
https://pubmed.ncbi.nlm.nih.gov/2124152
Publikováno v:
Blood. 69:1300-1306
Mepacrine uptake into platelets and bone marrow megakaryocytes was analyzed to further characterize the dense granule defects in a group of seven mouse pigment mutants that have characteristics of platelet storage pool disease (SPD). In contrast to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ac112605bef2cfd6f88ca4c53a8098
https://doi.org/10.1182/blood.v69.5.1300.1300
https://doi.org/10.1182/blood.v69.5.1300.1300
Publikováno v:
Blood. 66(5)
Two human diseases of platelet storage pool deficiency (SPD), Hermansky- Pudlak syndrome and Chediak-Higashi syndrome, are recessively inherited disorders characterized by hypopigmentation, prolonged bleeding, and normal platelet counts accompanied b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced6904110712437683049f3fc87a5b0
https://pubmed.ncbi.nlm.nih.gov/3902123
https://pubmed.ncbi.nlm.nih.gov/3902123
Publikováno v:
Blood. 57(1)
The mouse pigment mutant pale ear, ep/ep, which has a defect in kidney lysosomal enzyme secretion, had prolonged bleeding on experimental injury. Platelet counts and platelet protein did not differ from normal. There was, however, a deficiency in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7469cdf5cb56fc2e6659f4fe938bf4b
https://pubmed.ncbi.nlm.nih.gov/7448413
https://pubmed.ncbi.nlm.nih.gov/7448413
Autor:
Guo X; Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA., Tu L, Gumper I, Plesken H, Novak EK, Chintala S, Swank RT, Pastores G, Torres P, Izumi T, Sun TT, Sabatini DD, Kreibich G
Publikováno v:
Traffic (Copenhagen, Denmark) [Traffic] 2009 Sep; Vol. 10 (9), pp. 1350-61. Date of Electronic Publication: 2009 May 26.
Autor:
Chintala S; Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY, USA. sreenivasulu.chintala@roswellpark.org, Novak EK, Spernyak JA, Mazurchuk R, Torres G, Patel S, Busch K, Meeder BA, Horowitz JM, Vaughan MM, Swank RT
Publikováno v:
Brain research [Brain Res] 2009 Apr 17; Vol. 1266, pp. 18-28. Date of Electronic Publication: 2009 Feb 27.