Zobrazeno 1 - 10
of 216
pro vyhledávání: '"EIF5A2"'
Autor:
Fang Jianwen, Yu Tianze, Jiang Xiaocong, Lu Yuexin, Shang Xi, Shen Haixing, Lu Yue, Zheng Jingyan, Fu Peifen
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 101-9 (2024)
In cancer biology, the aberrant overexpression of eukaryotic translation initiation factor 5A2 (EIF5A2) has been correlative with an ominous prognosis, thereby underscoring its pivotal role in fostering metastatic progression. Consequently, EIF5A2 ha
Externí odkaz:
https://doaj.org/article/11ea566d683647d1bf1f1a7af543965d
Autor:
Yuwei Liu, Li Peng, Jing Chen, Ling Chen, Ying Wu, Mengxin Cheng, Min Chen, Xujun Ye, Yalei Jin
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Post-transcriptional regulation plays a critical role in controlling biological processes such as aging. Previous studies have shown that eukaryotic initiation factor 5A (EIF5A) might play a crucial role in aging. It is unknown wh
Externí odkaz:
https://doaj.org/article/51e53d16a6044c7bb0aa17a3612dd71b
Autor:
Chad R. Schultz, Ryan D. Sheldon, Huirong Xie, Elena Y. Demireva, Katie L. Uhl, Dalen W. Agnew, Dirk Geerts, André S. Bachmann
Publikováno v:
Biology Open, Vol 12, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/ff03a24cbd904c6da12eb4d5b15a39df
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 48, Iss 6, Pp 617-624 (2021)
Objective To detect the expression of EIF5A2 in hepatocellular carcinoma(HCC) and to explore its relation with clinicopathological characters and prognosis of HCC patients. Methods The expression of EIF5A2 mRNA and protein in 12 pairs of fresh HCC an
Externí odkaz:
https://doaj.org/article/a5551cf75194424a8c4745ea39a48e86
Autor:
Guannan Zhao, Wenjing Zhang, Peixin Dong, Hidemichi Watari, Yuqi Guo, Lawrence M. Pfeffer, Gabor Tigyi, Junming Yue
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Background Epithelial to mesenchymal transition (EMT) contributes to tumor metastasis and chemoresistance. Eukaryotic initiation factor 5A2 (EIF5A2) is highly expressed in a variety of human cancers but rarely expressed in normal tissues. Wh
Externí odkaz:
https://doaj.org/article/a4921d9835c14a0984f39ce2b3264a25
Autor:
Kun Wang, Yiyang Wang, Yuanjian Wang, Shujie Liu, Chunyan Wang, Shuo Zhang, Tianli Zhang, Xingsheng Yang
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background Ovarian cancer stem cells (OCSC), endowed with tumor-initiating and self-renewal capacity, would account not only for the tumor growth, the peritoneal metastasis, and the relapse, but also for the acquisition of chemotherapy resis
Externí odkaz:
https://doaj.org/article/015a3eb1f1e34b62aa88e9fd6ad0b2f1
Autor:
Lin Jiang, Yingjing Zhang, Pengfei Su, Zhiqiang Ma, Xin Ye, Weiming Kang, Yuqin Liu, Jianchun Yu
Publikováno v:
Translational Oncology, Vol 18, Iss , Pp 101351- (2022)
Background: Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide and chemoresistance is a major cause for its poor prognosis. Long non-coding RNAs (lncRNAs) are associated with cancer chemoresistance. The current study
Externí odkaz:
https://doaj.org/article/fac61b42af9a4ca898853e24a861f066
Publikováno v:
Diagnostic Pathology, Vol 15, Iss 1, Pp 1-13 (2020)
Abstract Background The involvement of circular RNAs (circRNAs) in chemoresistance of tumors has been identified. Herein, this study aims to investigate the role and the underlying mechanism of circ_0003998 in doxorubicin (DOX) resistance in hepatoce
Externí odkaz:
https://doaj.org/article/00ad70a284d04db394768d453b4e2dc9
Autor:
Wenkang Luan, Yuting Ding, Haitao Yuan, Shaojun Ma, Hongru Ruan, Jinlong Wang, Feng Lu, Xuefeng Bu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Long intergenic non-protein coding RNA 520 (LINC00520), a novel identified lncRNA, has been shown to modulate the malignant phenotype of tumor cells in some malignant tumors. However, the exact role and molecular mechanism of LINC
Externí odkaz:
https://doaj.org/article/21110f53d4bc42e99b6bbfd1e110f0ea
Publikováno v:
Kidney & Blood Pressure Research, Vol 45, Iss 3, Pp 477-496 (2020)
Objective: Coronary artery disease (CAD) is a cardiovascular disease that poses a fatal threat to human health, and the identification of potential biomarkers may help to delineate its pathophysiological mechanisms. Accumulating evidence has implicat
Externí odkaz:
https://doaj.org/article/273b1d1996c443dfa4073dc4738eb811