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Immunological and Epidemiological Aspects of the Immunogenicity of Streptococcus Pneumoniae Serotype 3 Capsular Polysaccharide in Pneumococcal Vaccines

Autor: E. A. Kurbatova, E. V. Sukhova, Nikolay E. Nifantiev, A. E. Zaitsev, Egorova Nb

Publikováno v: Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 97, Iss 1, Pp 72-82 (2020)

The introduction of pneumococcal vaccines into national immunization programmes around the world has reduced the incidence of pneumococcal vaccine serotypes, but had no influence on the incidence of Streptococcus pneumoniae serotype 3 included in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c1fad5a8e2ba384e198a3571ae1264
https://microbiol.elpub.ru/jour/article/view/531

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Higher Cytokine and Opsonizing Antibody Production Induced by Bovine Serum Albumin (BSA)-Conjugated Tetrasaccharide Related to Streptococcus pneumoniae Type 3 Capsular Polysaccharide

Autor: Egorova Nb, Nelli Akhmatova, Elina A. Akhmatova, E. V. Sukhova, Yury E. Tsvetkov, Anton E Zaytsev, E. A. Kurbatova, Nikolay E. Nifantiev, Natalya E. Yastrebova, Dmitriy V. Yashunsky

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

A number of studies have demonstrated the limited efficacy ofS. pneumoniaetype 3 capsular polysaccharide (CP) in the 13-valent pneumococcal conjugate vaccine against serotype 3 invasive pneumococcal diseases and carriage. Synthetic oligosaccharides (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a45a7826c837209acba9580486060b3
https://doi.org/10.3389/fimmu.2020.578019

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SYNTHETIC CONJUGATED ANALOGUES OF CAPSULE POLYSACCHARIDES OF PNEUMOCOCCUS - AN INSTRUMENT FOR DETECTION OF POST-VACCINATION ANTIBODIES

Autor: D. V. Yashunsky, Egorova Nb, N. E. Yastrebova, E. A. Kurbatova, E. V. Sukhova, E. A. Akhmatova, Yu. E. Tsvetkov, Nelli Akhmatova, Nikolay E. Nifantiev

Publikováno v: Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 6, Pp 54-60 (2016)

Aim. Evaluation of the ability of capsule polysaccharides (CP) of Streptococcus pneumoniae serotype 3 and 14 and their synthetic structure analogues, conjugated with bovine serum albumin (BSA), to detect antibodies in post-vaccination sera of mice. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222eabe1fbbc6f1c6d4bd0da62923d32
https://microbiol.elpub.ru/jour/article/view/105

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The use of biotinylated oligosaccharides related to fragments of capsular polysaccharides from Streptococcus pneumoniae serotypes 3 and 14 as a tool for assessment of the level of vaccine-induced antibody response to neoglycoconjugates

Autor: Nikolay E. Nifantiev, E. V. Sukhova, Nelli Akhmatova, E. A. Kurbatova, Egorova Nb, D. V. Yashunsky, E. E. Romanenko, N. E. Yastrebova, A. Yu. Leonova, E. A. Akhmatova, Marina L. Gening, Poddubikov Av, Yu. E. Tsvetkov

Publikováno v: Russian Chemical Bulletin. 65:1608-1616

In this report, the data are presented on the use of synthetic biotinylated oligosaccharides corresponding to different fragments of capsular polysaccharides (CP) from S. pneumoniae serotypes 3 and 14 for evaluation of the level of vaccine-induced an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47b81020e0a854a6f73048a550601694
https://doi.org/10.1007/s11172-016-1488-7

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Neoglycoconjugate of Tetrasaccharide Representing One Repeating Unit of the Streptococcus pneumoniae Type 14 Capsular Polysaccharide Induces the Production of Opsonizing IgG1 Antibodies and Possesses the Highest Protective Activity As Compared to Hexa- and Octasaccharide Conjugates

Autor: Marina L. Gening, E. V. Sukhova, E. A. Kurbatova, Elina A. Akhmatova, Nikolay E. Nifantiev, Nelli Akhmatova, Yury E. Tsvetkov, Egorova Nb, Natalya E. Yastrebova, Dmitriy V. Yashunsky

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

Identifying protective synthetic oligosaccharide (OS) epitopes of Streptococcus pneumoniae capsular polysaccharides (CPs) is an indispensable step in the development of third-generation carbohydrate pneumococcal vaccines. Synthetic tetra-, hexa-, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c6a8353f74b0c8bd12f1871c8633bc
https://doi.org/10.3389/fimmu.2017.00659

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The Effect of a BSA Conjugate of a Synthetic Hexasaccharide Related to the Fragment of Capsular Polysaccharide of Streptococcus pneumoniae Type 14 on the Activation of Innate and Adaptive Immune Responses

Autor: E. V. Sukhova, Nikolay E. Nifantiev, Yury E. Tsvetkov, D. V. Yashunsky, E. A. Kurbatova, E. A. Akhmatov, Egorova Nb, Marina L. Gening, Denis Y. Logunov, Nelli Akhmatova

Publikováno v: Frontiers in Immunology

We report the effect of a bovine serum albumin (BSA) conjugate of a synthetic hexasaccharide (HS) related to the fragment of the capsular polysaccharide (PS) of Streptococcus pneumoniae type 14 on the stimulation of innate immune system and the subse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a04aa6c6b8bc34a5a9dd3f7b10d1c1c

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Activation of Innate Immunity by Bacterial Ligands of Toll-Like Receptors

Autor: Egorova Nb, E. A. Akhmatov, Nelli Akhmatova, E. A. Kurbatova

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 5 (2014)

Tγδ and B1 lymphocytes are essential components of the mucosal immune system, activated directly by different bacterial and viral ligands without additional costimulatory signals and preprocessing of other immune effectors. This ability enables the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bec4eff3841d9900a82a231c66f812

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