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of 162
pro vyhledávání: '"EGFR-targeted therapy"'
Akademický článek
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Autor:
Chengyang Song, Xueying Yang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Osimertinib is a third-generation, irreversible mutant epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that is approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA). Osimertinib is currently the
Externí odkaz:
https://doaj.org/article/cdd7ad1e94ae4b97b9dc6f62117b723e
Autor:
Suphalak Khamruang Marshall, Boonyisa Saelim, Maneerat Taweesap, Verachai Pachana, Yada Panrak, Naritsara Makchuchit, Passara Jaroenpakdee
Publikováno v:
Nanomaterials, Vol 12, Iss 19, p 3517 (2022)
The systemic delivery of doxorubicin (DOX) to treat osteosarcoma requires an adequate drug concentration to be effective, but in doing so, it raises the risk of increasing organ off-target toxicity and developing drug resistance. Herein, this study r
Externí odkaz:
https://doaj.org/article/bca0caf96c5f48488475bf28d854bd7d
Autor:
Ronan P. McLaughlin, Jichao He, Vera E. van der Noord, Jevin Redel, John A. Foekens, John W. M. Martens, Marcel Smid, Yinghui Zhang, Bob van de Water
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Abstract Background The effective treatment of triple-negative breast cancer (TNBC) remains a profound clinical challenge. Despite frequent epidermal growth factor receptor (EGFR) overexpression and reliance on downstream signalling pathways in TNBC,
Externí odkaz:
https://doaj.org/article/d7a9858eb35e4f8bbbf909c779d15779
Autor:
Seda EREN KESKİN, Eda GÜZDOLU, Nilüfer SERTDEMİR, Gülhan DEMİR, Deniz SÜNNETÇİ AKKOYUNLU, Devrim ÇABUK, Naci ÇİNE, Hakan SAVLI
Publikováno v:
Volume: 8, Issue: 3 172-178
Kocaeli Üniversitesi Sağlık Bilimleri Dergisi
Kocaeli Üniversitesi Sağlık Bilimleri Dergisi
Amaç: RAS genleri, Epidermal Büyüme Faktörü Reseptörü (EGFR) tarafından indüklenen RAS-MAPK Sinyal yolağının bir üyesidir. Bu yolaktaki genlerde meydana gelen mutasyonlar kanser gelişimini tetiklemektedir. Kolorektal kanserde (KRK), RAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e544058272f794db89b939d49156de9
https://doi.org/10.30934/kusbed.1052876
https://doi.org/10.30934/kusbed.1052876
Autor:
Prashanth Rajaram, Poornima Chandra, Smriti Ticku, B K Pallavi, K B Rudresh, Poorva Mansabdar
Publikováno v:
Indian Journal of Dental Research, Vol 28, Iss 6, Pp 687-694 (2017)
Cells are constantly exposed to various external stimuli which regulate the growth and survival of the cells. The signal transduction from the external environment to the interior of the cell is carried out by cell surface or transmembrane receptors.
Externí odkaz:
https://doaj.org/article/d995880686f34f82ba6c6d3b70f23d4e
Akademický článek
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Autor:
Czachorowski, Abriel Malin
Publikováno v:
Czachorowski, Abriel Malin. PCI-based Targeted Therapy for Treatment Resistant Sarcoma. Master thesis, University of Oslo, 2019
Externí odkaz:
http://hdl.handle.net/10852/70621
https://www.duo.uio.no/bitstream/handle/10852/70621/1/AbrielCzachorowskiMastersThesis.pdf
https://www.duo.uio.no/bitstream/handle/10852/70621/1/AbrielCzachorowskiMastersThesis.pdf
Akademický článek
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Autor:
Jonathan W. Riess, Justin A. Chen
Publikováno v:
J Thorac Dis
Next-generation sequencing (NGS) of tumor samples and circulating tumor DNA has revolutionized diagnostic and therapeutic strategies in lung cancer. The identification of the epidermal growth factor receptor (EGFR) oncogenic driver has translated int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a8aa4604e0cfe3a19da8f2e6c68b82
https://doi.org/10.21037/jtd.2019.08.32
https://doi.org/10.21037/jtd.2019.08.32