Zobrazeno 1 - 10
of 17
pro vyhledávání: '"EGFP, Enhanced Green Fluorescence Protein"'
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Gene therapy has been widely investigated for the treatment of genetic, acquired, and infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of causing serious adverse events, resulting in th
Gene therapy has been widely investigated for the treatment of genetic, acquired, and infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of causing serious adverse events, resulting in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7413733ccbe4eda7411005d2c1ea69
http://europepmc.org/articles/PMC8518240
http://europepmc.org/articles/PMC8518240
Publikováno v:
The Journal of Biological Chemistry
As a central player in the canonical TGF-β signaling pathway, Smad2 transmits the activation of TGF-β receptors at the plasma membrane (PM) to transcriptional regulation in the nucleus. Although it has been well established that binding of TGF-β t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef605ebedf237cc470093be8d892be72
https://pubmed.ncbi.nlm.nih.gov/34655614
https://pubmed.ncbi.nlm.nih.gov/34655614
Autor:
Pankaj J. Pasricha, Yu-Wen Tien, Chi Che Hsieh, Subhash Kulkarni, Yung-Ming Jeng, Mei Hsin Chung, Ya Hsien Chou, Tsai Chen Chiang, King Siang Goh, Chia-Ning Shen, Hung Jen Chien, Chi Ruei Huang, Shih Jung Peng, Shiue-Cheng Tang, Chih Yuan Lee
Publikováno v:
EBioMedicine
Background The lymphatic system is involved in metastasis in pancreatic cancer progression. In cancer staging, lymphatic spread has been used to assess the invasiveness of tumor cells. However, from the endothelium's perspective, the analysis downpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decbe457f6ec2735f5478f710ca5467b
http://europepmc.org/articles/PMC6796580
http://europepmc.org/articles/PMC6796580
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100084-(2021)
Journal of Lipid Research
Journal of Lipid Research
Cholesterol is an essential component of the mammalian plasma membrane involved in diverse cellular processes. Our recent quantitative imaging analysis using ratiometric cholesterol sensors showed that the available cholesterol concentration in the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98998a9fabc83fa3193c8196f2d33e15
http://www.sciencedirect.com/science/article/pii/S0022227521000663
http://www.sciencedirect.com/science/article/pii/S0022227521000663
Autor:
Bénédicte Brulin, Unmesh Jadhav, Philippe Crespy, Zeinab Homayed, Jihane Boubaker-Vitre, Fanny Grillet, J. Hazerbroucq, Frédéric Hollande, Cyril Breuker, Julie Giraud, Christine Pignodel, J-F. Bourgaux, Ramesh A. Shivdasani, Philippe Jay, Julie Pannequin, Momeneh Foroutan
Publikováno v:
Translational Oncology
Translational Oncology, 2020, 14 (2), pp.101001. ⟨10.1016/j.tranon.2020.101001⟩
Translational Oncology, Vol 14, Iss 2, Pp 101001-(2021)
Translational Oncology, Elsevier, 2020, 14 (2), pp.101001. ⟨10.1016/j.tranon.2020.101001⟩
Translational Oncology, 2020, 14 (2), pp.101001. ⟨10.1016/j.tranon.2020.101001⟩
Translational Oncology, Vol 14, Iss 2, Pp 101001-(2021)
Translational Oncology, Elsevier, 2020, 14 (2), pp.101001. ⟨10.1016/j.tranon.2020.101001⟩
Highlights • Secretion of progastrin is a signature event of early malignant transformation in the colon. • In the healthy epithelium, progastrin is produced by a subset of enteroendocrine cells expressing both Bmi1 and Prox1. • LGR5-high intes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edac14cd110ff4d56111788f49ee3dd
https://hal.science/hal-03090781
https://hal.science/hal-03090781
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 3, Pp 484-499 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Hepatocellular carcinoma (HCC) occurs more frequently and aggressively in men than in women. Although sex hormones are believed to play a critical role in this disparity, the possible contribution of other factors largely is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ddb6ec1a66e6c4f750e0f154046117
http://www.sciencedirect.com/science/article/pii/S2352345X17300048
http://www.sciencedirect.com/science/article/pii/S2352345X17300048
Autor:
Yasuaki Shirayoshi, Kohei Fukuoka, Kumi Morikawa, Yoshiko Suyama, Shunjiro Yagi, Kazuomi Nakamura, Kenshiro Yamamoto, Tetsuya Ohbayashi, Ichiro Hisatome
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 18, Iss, Pp-(2019)
Biochemistry and Biophysics Reports, Vol 18, Iss, Pp-(2019)
In the present study, we have established a novel transgenic mouse and transgenic rats with dual reporters of EGFP and ELuc. In these transgenic (Tg) rodents, both GFP fluorescent and luciferase luminescent signals were ubiquitously detected in the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3ff2dc0bfce64d3be01b86a85a9ef8
https://pubmed.ncbi.nlm.nih.gov/31193220
https://pubmed.ncbi.nlm.nih.gov/31193220
Autor:
Kortus, Stepan, Srinivasan, Chinnapaiyan, Forostyak, Oksana, Ueta, Yoichi, Sykova, Eva, Chvatal, Alexandr, Zapotocky, Martin, Verkhratsky, Alexei, Dayanithi, G.
Publikováno v:
Cell Calcium
Cell Calcium, Elsevier, 2016, 59 (6), pp.280-288. ⟨10.1016/j.ceca.2016.04.001⟩
Kortus, S, Srinivasan, C, Forostyak, O, Ueta, Y, Sykova, E, Chvatal, A, Zapotocky, M, Verkhratsky, A & Dayanithi, G 2016, ' Physiology of spontaneous [Ca2+]i oscillations in the isolated vasopressin and oxytocin neurones of the rat supraoptic nucleus ', Cell calcium, vol. 59, no. 6, pp. 280–288 . https://doi.org/10.1016/j.ceca.2016.04.001
Cell Calcium, 2016, 59 (6), pp.280-288. ⟨10.1016/j.ceca.2016.04.001⟩
Cell Calcium, Elsevier, 2016, 59 (6), pp.280-288. ⟨10.1016/j.ceca.2016.04.001⟩
Kortus, S, Srinivasan, C, Forostyak, O, Ueta, Y, Sykova, E, Chvatal, A, Zapotocky, M, Verkhratsky, A & Dayanithi, G 2016, ' Physiology of spontaneous [Ca2+]i oscillations in the isolated vasopressin and oxytocin neurones of the rat supraoptic nucleus ', Cell calcium, vol. 59, no. 6, pp. 280–288 . https://doi.org/10.1016/j.ceca.2016.04.001
Cell Calcium, 2016, 59 (6), pp.280-288. ⟨10.1016/j.ceca.2016.04.001⟩
Graphical abstract Trace (A) shows a typical transient [Ca2+]i response induced by 50 mM K+ observed in an AVP-eGFP neurone (inset), Trace (B) shows the spontaneous [Ca2+]i oscillations observed in an AVP-eGFP neurone (inset). The corresponding chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::18c54c6289f0d3567f513614506fe15a
Publikováno v:
Meta Gene
As an indispensable component of the eukaryotic ribosome, ribosomal protein L23a plays an important role in protein synthesis, folding and sorting. In this study, the cDNA fragment of ribosomal protein L23a with 471 bp in size was screened from the S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d8693b6a9ee8d7737bdd2b6dbbb8be
https://doi.org/10.1016/j.mgene.2014.06.005
https://doi.org/10.1016/j.mgene.2014.06.005
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 387-392 (2014)
FEBS Open Bio
FEBS Open Bio
Graphical abstract
Highlights • We revealed the intra-molecular interaction of DGKα. • The EF-hand motifs of DGKα directly binds to its C1 domains. • The intra-molecular interaction was negatively regulated by Ca2+. • The intra-molecul
Highlights • We revealed the intra-molecular interaction of DGKα. • The EF-hand motifs of DGKα directly binds to its C1 domains. • The intra-molecular interaction was negatively regulated by Ca2+. • The intra-molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8393091b2002da3bfd717343e85672c
http://www.sciencedirect.com/science/article/pii/S2211546314000394
http://www.sciencedirect.com/science/article/pii/S2211546314000394