Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis

Autor: Laura Rossi, Waliul I. Khan, Jean-Eric Ghia, Steve P. Bernier, Stephen M. Collins, Emmanuel Denou, Suhrid Banskota, Md. Sharif Shajib, Michelle E. Fontes, Huaqing Wang, Yun Han Kwon, Michael G. Surette

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 709-728 (2019)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Serotonin (5-hydroxytryptamine [5-HT]) is synthesized mainly within enterochromaffin (EC) cells in the gut, and tryptophan hydroxylase 1 (Tph1) is the rate-limiting enzyme for 5-HT synthesis in EC cells. Accumulating evidence sugges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d7b958a4788fee643381de67358945
https://doi.org/10.1016/j.jcmgh.2019.01.004