Zobrazeno 1 - 10
of 55
pro vyhledávání: '"EDGAR MAQUIGUSSA"'
Autor:
Bruno Aristides dos Santos Bronel, Edgar Maquigussa, Mirian Aparecida Boim, Antônio da Silva Novaes
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The fibrogenic process plays a significant pathophysiological role in the progression of chronic kidney disease. Inhibition of the renin-angiotensin system (RAS) is one strategy to delay disease progression but does not reverse established f
Externí odkaz:
https://doaj.org/article/dccc97357af0456191b9a89ebf255e59
Autor:
Bruno Aristides dos Santos Bronel, Ana Carolina Anauate, Edgar Maquigussa, Mirian Aparecida Boim, Antônio da Silva Novaes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Reverse transcription-quantitative polymerase chain reaction (RT-PCR) is the gold standard technique for gene expression analysis, but the choice of quantitative reference genes (housekeeping genes, HKG) remains challenging. Identify the bes
Externí odkaz:
https://doaj.org/article/42093dede20945048b92079ec64a7e95
Autor:
Carolina Carvalho Serres Da-Silva, Ana Carolina Anauate, Tatiana Pinotti Guirao, Antônio da Silva Novaes, Edgar Maquigussa, Mirian Aparecida Boim
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Sepsis contributes to the high prevalence of acute kidney injury (AKI), which mainly occurs in hospitalized patients. The delay in AKI detection is a risk factor for death and chronicity; thus, early diagnosis is essential for initiating proper treat
Externí odkaz:
https://doaj.org/article/3ca733db854c4a438a3381929051e26b
Autor:
Vanessa Araujo Varela, Elizabeth B. Oliveira-Sales, Edgar Maquigussa, Fernanda T. Borges, Pedro P. Gattai, Antonio da S. Novaes, Caroline G. Shimoura, Ruy R. Campos, Mirian A. Boim
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-12 (2019)
Background: Mesenchymal stem cells (MSC) improve renal function and renovascular hypertension in the 2-kidney 1-clip model (2K-1C). While MSC play an immunomodulatory role, induce neoangiogenesis, and reduce fibrosis, they do not correct sodium loss
Externí odkaz:
https://doaj.org/article/e4953a97c4a142ffba2200b52f7e8759
Autor:
Roberta Facioli, Fernando Henrique Lojudice, Ana Carolina Anauate, Edgar Maquigussa, José Luiz Nishiura, Ita Pfeferman Heilberg, Mari Cleide Sogayar, Mirian Aparecida Boim
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Background Kidney organoids have been broadly obtained from commercially available induced pluripotent stem cells (iPSCs); however, it has been a great challenge to efficiently produce renal organoid models from patients with autosomal dominant polyc
Externí odkaz:
https://doaj.org/article/4ad321816dcc418f89f48950f1f3a7ae
Autor:
Crysthiane Saveriano Rubiao Andre Ishiy, Milene Subtil Ormanji, Edgar Maquigussa, Rosemara Silva Ribeiro, Antonio da Silva Novaes, Mirian Aparecida Boim
Publikováno v:
Stem Cells International, Vol 2020 (2020)
Background. Chronic renal artery stenosis is considered one of the most common causes of renovascular hypertension (RH). Chronic hypoxia can lead to irreversible damage to renal tissue and to a progressive deterioration of renal function. We have pre
Externí odkaz:
https://doaj.org/article/183601e0e257438493d992f4fed3b165
Autor:
Edgar Maquigussa, Josne C. Paterno, Gabriel H. de Oliveira Pokorny, Mariana da Silva Perez, Vanessa A. Varela, Antônio da Silva Novaes, Nestor Schor, Mirian A. Boim
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Renin angiotensin system (RAS) blockade reduces the progression of chronic kidney disease (CKD) independently of its antihypertensive effect. Ang II-induced fibrosis can be mediated by molecules such as klotho, peroxisome proliferator-activate recept
Externí odkaz:
https://doaj.org/article/68f9f77649974c2d8ae9ab856253f374
Autor:
Rosemara S Ribeiro, Clevia S Passos, Antônio S Novaes, Edgar Maquigussa, Maria A Glória, Iria Visoná, Olinda Ykuta, Lila M Oyama, Mirian A Boim
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174721 (2017)
Obesity and its consequences can damage the kidney over time. However, less is known about the impact of developing overweight/obesity during childhood on the kidney in adulthood and the renal impact of a superimposed acute kidney injury (AKI). This
Externí odkaz:
https://doaj.org/article/a490d3cb577440d3889130ca5ea774bb
Autor:
Vanessa Meira Ferreira, Clevia Santos Passos, Edgar Maquigussa, Roberto Braz Pontes, Cassia Toledo Bergamaschi, Ruy Ribeiro Campos, Mirian Aparecida Boim
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150096 (2016)
Pregnancy is characterized by maternal systemic and intrarenal vasodilation, leading to increases in the renal plasma flow (RPF) and glomerular filtration rate (GFR). These responses are mainly mediated by nitric oxide (NO) and relaxin. The impact of
Externí odkaz:
https://doaj.org/article/cacc0d0a1c9844b0970231227ebcbaf3
Autor:
Elizabeth B Oliveira-Sales, Edgar Maquigussa, Patricia Semedo, Luciana G Pereira, Vanessa M Ferreira, Niels O Câmara, Cassia T Bergamaschi, Ruy R Campos, Mirian A Boim
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78464 (2013)
Renovascular hypertension induced by 2 Kidney-1 Clip (2K-1C) is a renin-angiotensin-system (RAS)-dependent model, leading to renal vascular rarefaction and renal failure. RAS inhibitors are not able to reduce arterial pressure (AP) and/or preserve th
Externí odkaz:
https://doaj.org/article/7162b2dd17694d8583ef99be8f992457