Zobrazeno 1 - 10
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pro vyhledávání: '"EDEN, R."'
Autor:
Tong Tong, Congcong Zhu, John J. Farrell, Zainab Khurshid, Alzheimer’s Disease Sequencing Project, Alzheimer’s Disease Neuroimaging Initiative, Eden R. Martin, Margaret A. Pericak-Vance, Li-San Wang, William S. Bush, Gerard D. Schellenberg, Jonathan L. Haines, Wei Qiao Qiu, Kathryn L. Lunetta, Lindsay A. Farrer, Xiaoling Zhang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Blood-derived mitochondrial DNA copy number (mtDNA-CN) is a proxy measurement of mitochondrial function in the peripheral and central systems. Abnormal mtDNA-CN not only indicates impaired mtDNA replication and transcription machi
Externí odkaz:
https://doaj.org/article/6359a6836b184b369a74d2bbfb50ce84
Autor:
Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma, X. Steven Chen, Brian Kunkle, Eden R. Martin, Lily Wang
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
DNA methylation (DNAm) plays a crucial role in a number of complex diseases. However, the reliability of DNAm levels measured using Illumina arrays varies across different probes. Previous research primarily assessed probe reliability by comparing du
Externí odkaz:
https://doaj.org/article/4ce06caaeaea44738879447256113558
Publikováno v:
Systematic Reviews, Vol 13, Iss 1, Pp 1-8 (2024)
Abstract Background Hematopoietic stem cell transplantation (HSCT) is a life-saving treatment for adolescents and young adults (ages 15–39) with hematologic malignancy. Given the significant developmental milestones usually achieved during this uni
Externí odkaz:
https://doaj.org/article/7e4fa5969a6146fa99957a79b75b7360
Autor:
Huang, Jaxon J., Rodriguez, Daniel A., Slifer, Susan H., Martin, Eden R., Levitt, Roy C., Galor, Anat
Publikováno v:
In Ophthalmology Science March-April 2024 4(2)
Autor:
Jaxon J. Huang, BHSc, Daniel A. Rodriguez, MD, PhD, Susan H. Slifer, MSc, Eden R. Martin, PhD, Roy C. Levitt, MD, Anat Galor, MD, MSPH
Publikováno v:
Ophthalmology Science, Vol 4, Iss 2, Pp 100384- (2024)
Purpose: To conduct a genome-wide association study (GWAS) of individuals with neuropathic ocular pain (NOP) symptoms to identify genomic variants that may predispose to NOP development. Design: Prospective study of individuals with NOP. Participants
Externí odkaz:
https://doaj.org/article/623c100914ec4dde94bdaa7c47d8fa6f
Akademický článek
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Autor:
Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Growing evidence has demonstrated that DNA methylation (DNAm) plays an important role in Alzheimer’s disease (AD) and that DNAm differences can be detected in the blood of AD subjects. Most studies have correlated blood DNAm wit
Externí odkaz:
https://doaj.org/article/ae8faa0469a948dca7ff5ab04c03229a
Autor:
Xiaoyi Raymond Gao, Marion Chiariglione, Ke Qin, Karen Nuytemans, Douglas W. Scharre, Yi-Ju Li, Eden R. Martin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Alzheimer’s disease (AD) is the most common late-onset neurodegenerative disorder. Identifying individuals at increased risk of developing AD is important for early intervention. Using data from the Alzheimer Disease Genetics Consortium, w
Externí odkaz:
https://doaj.org/article/76e2d7cbc8184a7880c9eaf687d4b05e
Autor:
Tiago C. Silva, Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background Sex is increasingly recognized as a significant factor contributing to the biological and clinical heterogeneity in AD. There is also growing evidence for the prominent role of DNA methylation (DNAm) in Alzheimer’s disease (AD).
Externí odkaz:
https://doaj.org/article/673535fab72c471f815ef846cc8b2bcd
Autor:
Tiago C. Silva, Juan I. Young, Lanyu Zhang, Lissette Gomez, Michael A. Schmidt, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
DNA methylation differences in Alzheimer’s disease have been previously reported, although the interpretation of the differences is unclear. Here, the authors performed epigenome-wide meta-analyses of DNA methylation in blood and brain, and develop
Externí odkaz:
https://doaj.org/article/43df6e2bbc7a4b2eb04e9c03de3ff40c