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pro vyhledávání: '"ECM–extracellular matrix"'
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Tumor-associated macrophages (TAMs), fundamental constituents of the tumor microenvironment (TME), significantly influence cancer development, primarily by promoting epithelial-mesenchymal transition (EMT). EMT endows cancer cells with increased moti
Externí odkaz:
https://doaj.org/article/5181cfe6c6524cf78497e78f84773d76
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/9c535efc690a4560a96605e578d79cbc
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
It has been known for decades that the tumor extracellular matrix (ECM) is dysfunctional leading to loss of tissue architecture and promotion of tumor growth. The altered ECM and tumor fibrogenesis leads to tissue stiffness that act as a physical bar
Externí odkaz:
https://doaj.org/article/f18f4fb63fd74d4aaf0dd5c1f40c603d
Autor:
Dan Liang, Lu Liu, Yunjie Zhao, Zhenyi Luo, Yadi He, Yanping Li, Shiyun Tang, Jianyuan Tang, Nianzhi Chen
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Extracellular matrix (ECM) plays a pivotal and dynamic role in the construction of tumor microenvironment (TME), becoming the focus in cancer research and treatment. Multiple cell signaling in ECM remodeling contribute to uncontrolled proliferation,
Externí odkaz:
https://doaj.org/article/a3e4008dbd7746c8ae99bcf743fbeaef
Autor:
Yoshimasa, Yushi1 (AUTHOR), Takao, Tomoka1,2 (AUTHOR), Katakura, Satomi1,3 (AUTHOR), Tomisato, Shoko1 (AUTHOR), Masuda, Hirotaka1,4 (AUTHOR), Tanaka, Mamoru1 (AUTHOR), Maruyama, Tetsuo1 (AUTHOR) tetsuo@keio.jp
Publikováno v:
International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 8, p7605. 12p.
Autor:
Karousou, Evgenia1 (AUTHOR), Parnigoni, Arianna1 (AUTHOR), Moretto, Paola1 (AUTHOR), Passi, Alberto1 (AUTHOR), Viola, Manuela1 (AUTHOR) manuela.viola@uninsubria.it, Vigetti, Davide1 (AUTHOR)
Publikováno v:
Cancers. Feb2023, Vol. 15 Issue 3, p798. 13p.
Publikováno v:
The Journal of Nutritional Biochemistry. 13:421-426
Genistein and daidzein are two major isoflavonoids in dietary soybean that have inhibition effect on the cell growth of different tumor cell lines. We previously reported the anti-tumor activities of genistein and daidzein in human co1on tumor (HCT)
Autor:
Subhajit Konar, Scott M. Bolam, Brendan Coleman, Nicola Dalbeth, Sue R. McGlashan, Sophia Leung, Jillian Cornish, Dorit Naot, David S. Musson
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Tendinopathy is characterised by pathological changes in tendon matrix composition, architecture, and stiffness, alterations in tendon resident cell characteristics, and fibrosis, with inflammation also emerging as an important factor in tendinopathy
Externí odkaz:
https://doaj.org/article/bf4f312d8a9d46f681f0ca26cddf7c38
Autor:
Nan Li, Shan Shan, Xiu-Qin Li, Ting-Ting Chen, Meng Qi, Sheng-Nan Zhang, Zi-Ying Wang, Ling-Ling Zhang, Wei Wei, Wu-Yi Sun
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
G protein-coupled receptor kinase 2 (GRK2), an important subtype of GRKs, specifically phosphorylates agonist-activated G protein-coupled receptors (GPCRs). Besides, current research confirms that it participates in multiple regulation of diverse cel
Externí odkaz:
https://doaj.org/article/40834aff4d454f3f8b9d8a6e12e781fe