Výsledky vyhledávání - "ECL, enhanced chemiluminescence"

Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-α 1 1Abbreviations: EGb 761, Ginkgo biloba extract; LPS, lipopolysaccharide; ROIs, reactive oxygen intermediates; TNF, tumor necrosis factor; IL, interleukin; COX, cyclooxygenase; iNOS, inducible nitric oxide synthase; TLR, Toll-like receptor; LBP, lipid binding protein; NF-κB, nuclear factor-κB; IKK, IκB kinase; AP-1, activator protein 1; ATF, activating transcription factor; CRE, cyclic AMP response element; CREB, cyclic AMP binding protein; C/EBP, CCAAT/enhancer binding protein; ARE, AU-rich element; -UTR, untranslated region; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-related kinase; MEKK, MAPK/ERK kinase kinase; MEK, MAPK/ERK kinase; JNK/SAPK, Jun N terminal kinase/stress-activated protein kinase; EMSA, electrophoretic mobility shift assay; DTT, dithiothreitol; PMSF, phenylmethylsulfonyl fluoride; and ECL, enhanced chemiluminescence

Autor: Dennis R. Koop, Tasha L. McDonald, Teri L. Wadsworth

Publikováno v: Biochemical Pharmacology. 62:963-974

Administration of bacterial lipopolysaccharide (LPS) to laboratory animals and cultured macrophages induces tumor necrosis factor-alpha (TNF-alpha), a pro-inflammatory cytokine. Pretreatment with Ginkgo biloba extract (EGb 761) inhibited the in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97458a80577211be5a9ab594dcdbdbe7
https://doi.org/10.1016/s0006-2952(01)00734-1

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