Zobrazeno 1 - 10
of 49
pro vyhledávání: '"ECAR, Extracellular Acidification Rate"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1578-1591 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Limb and CNS expressed 1 like (LIX1L) is over-expressed in several types of tumors. However, the function of LIX1L in glucose metabolism and hepatocellular carcinoma (HCC) progression remains elusive. Here we report that LIX1L is over-expressed in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c970bf879a240521753514a3be8c82c
https://doi.org/10.1016/j.apsb.2021.02.005
https://doi.org/10.1016/j.apsb.2021.02.005
Autor:
Jan Koster, Pim J. Koelink, Manon van Roest, Sander Meisner, Ingrid B. Renes, William J. Faller, Joana Silva, Wouter L. Smit, Jacqueline L.M. Vermeulen, Manon E. Wildenberg, Vanesa Muncan, Ruurd M. van Elburg, Tânia Martins Garcia
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 943-981 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 12(3), 943-981. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 12(3), 943-981. Elsevier Inc.
Background & Aims The use of antibiotics (ABs) is a common practice during the first months of life. ABs can perturb the intestinal microbiota, indirectly influencing the intestinal epithelial cells (IECs), but can also directly affect IECs independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c861cf76325ee471195673d49383545
http://www.sciencedirect.com/science/article/pii/S2352345X21001132
http://www.sciencedirect.com/science/article/pii/S2352345X21001132
Autor:
Sara M. Dann, Zheng Zhou, Suxia Yao, Wenjing Yang, Anthony J. Bilotta, Yu Yu, Xiaojing Zhao, Chunyan Ma, Yingzi Cong, Yanbo Yu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1023-1044 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background and Aims Gut bacteria-derived short-chain fatty acids (SCFAs) play crucial roles in the maintenance of intestinal homeostasis. However, how SCFAs regulate epithelial turnover and tissue repair remain incompletely understood. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d4114ca3e9339e1b8954fbfbdd4b9d
http://www.sciencedirect.com/science/article/pii/S2352345X20301909
http://www.sciencedirect.com/science/article/pii/S2352345X20301909
Publikováno v:
Genes and Diseases, Vol 7, Iss 2, Pp 185-198 (2020)
Genes & Diseases
Genes & Diseases
The genetic alterations associated with cell transformation are in large measure expressed in the metabolic phenotype as cancer cells proliferate and change their local environment, and prepare for metastasis. Qualitatively, the fundamental biochemis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6609ae5ac656e8fc45b416014d29e6d
http://www.sciencedirect.com/science/article/pii/S2352304219300947
http://www.sciencedirect.com/science/article/pii/S2352304219300947
Autor:
Michael D. Onken, Sarah E. Noda, Kevin M. Kaltenbronn, Cheryl Frankfater, Carol M. Makepeace, Nikki Fettig, Kisha D. Piggott, Philip L. Custer, Joseph E. Ippolito, Kendall J. Blumer
Publikováno v:
The Journal of Biological Chemistry
Metabolic reprogramming has been shown to occur in uveal melanoma (UM), the most common intraocular tumor in adults. Mechanisms driving metabolic reprogramming in UM are poorly understood. Elucidation of these mechanisms could inform development of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75e9c1da7a1bf50b5ce0880b781fb6f
http://europepmc.org/articles/PMC8761705
http://europepmc.org/articles/PMC8761705
Autor:
Jiancheng Zheng, Yibo Gan, XuTan, Ziwen Wang, Chi Zhang, Aihua Zhang, Huilan Wang, Min Luo, Fengying Liao, Ziyuan Zhou, Chunmeng Shi, Lei Long, Yawei Wang, Yu Wang, Zelin Chen, Peng Luo, Long Chen, Yu Huang, Zeyu Yang, Zhongyong Jiang, Xueru Li, Yunsheng Liu
Publikováno v:
Redox Biology
Redox Biology, Vol 46, Iss, Pp 102082-(2021)
Redox Biology, Vol 46, Iss, Pp 102082-(2021)
Idiopathic pulmonary fibrosis (IPF) is characterized by excessive deposition of extracellular matrix in the lung with fibroblast-to-myofibroblast transition, leading to chronically compromising lung function and death. However, very little is known a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4878f68553a51237c244128186a685
https://pubmed.ncbi.nlm.nih.gov/34343908
https://pubmed.ncbi.nlm.nih.gov/34343908
Autor:
Hideto Osada, Eriko Toda, Yoko Ozawa, Hideyuki Okano, Norihiro Nagai, Kazuo Tsubota, Kohei Homma, Takumi Era
Publikováno v:
Redox Biology, Vol 41, Iss, Pp 101921-(2021)
Redox Biology
Redox Biology
Mitochondria participate in various metabolic pathways, and their dysregulation results in multiple disorders, including aging-related diseases. However, the metabolic changes and mechanisms of mitochondrial disorders are not fully understood. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300fe33887f387d26627d8e97f600360
http://www.sciencedirect.com/science/article/pii/S2213231721000690
http://www.sciencedirect.com/science/article/pii/S2213231721000690
Autor:
Morten, Dall, Anna S, Hassing, Lili, Niu, Thomas S, Nielsen, Lars R, Ingerslev, Karolina, Sulek, Samuel A J, Trammell, Matthew P, Gillum, Romain, Barrès, Steen, Larsen, Steen S, Poulsen, Matthias, Mann, Cathrine, Ørskov, Jonas T, Treebak
Publikováno v:
The Journal of Biological Chemistry
Nicotinamide phosphoribosyltransferase (NAMPT) converts nicotinamide to NAD+. As low hepatic NAD+ levels have been linked to the development of nonalcoholic fatty liver disease, we hypothesized that ablation of hepatic Nampt would affect susceptibili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65cfe1f1ba467bfc092fcef0e226a573
https://pubmed.ncbi.nlm.nih.gov/34762911
https://pubmed.ncbi.nlm.nih.gov/34762911
Autor:
Orla Prendiville, Noel E Donlon, Cara Dunne, Croí E. Buckley, Helen P. Berrigan, Timothy Nugent, Lorraine Brennan, J. O. Larkin, Michael Durand, Niamh Lynam-Lennon, Heleena Moni Bottu, Amy M. Buckley, Aisling B Heeran, Brian Mehigan, Jacintha O'Sullivan, Niamh Clarke, Paul McCormick
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100882-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100882-(2021)
Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy, however only 22% of patients achieve a complete response. Resistance mechanisms are poorly understood. Radiation-induced Bystander Effect (RIBE) describes the effect of rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7b36a639368d9167dde0b2fddde74d
http://europepmc.org/articles/PMC7586242
http://europepmc.org/articles/PMC7586242
Autor:
Dean G. Assimos, Vidhush K. Yarlagadda, Tanecia Mitchell, Vikram Saini, Oreoluwa O. Adedoyin, Ross P. Holmes, Mikita Patel
Publikováno v:
Redox Biology, Vol 15, Iss C, Pp 207-215 (2018)
Redox Biology
Redox Biology
Monocytes/macrophages are thought to be recruited to the renal interstitium during calcium oxalate (CaOx) kidney stone disease for crystal clearance. Mitochondria play an important role in monocyte function during the immune response. We recently det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32272e9d2d73be509f34657272136c90
http://www.sciencedirect.com/science/article/pii/S2213231717307565
http://www.sciencedirect.com/science/article/pii/S2213231717307565