Zobrazeno 1 - 10
of 2 706
pro vyhledávání: '"EC50- half maximal effective concentration"'
Autor:
Rodrigues, Thaina1,2 (AUTHOR) thaina.rodrigues@unesp.br, Busso, Jefferson de Souza1,2 (AUTHOR) jefferson.busso@unesp.br, Dias, Raphael Vinicius Rodrigues1 (AUTHOR) rvr.dias@unesp.br, Ottenio Lourenço, Isabella1,2 (AUTHOR) isabella.otenio@unesp.br, de Sa, Jessica Maróstica1,2 (AUTHOR) jessica.marostica@unesp.br, Carvalho, Sidney Jurado de1 (AUTHOR) sidney.carvalho@unesp.br, Caruso, Icaro Putinhon1,2 (AUTHOR) icaro.caruso@unesp.br, Souza, Fatima Pereira de1,2 (AUTHOR) fatima.p.souza@unesp.br, Fossey, Marcelo Andres1,2 (AUTHOR) marcelo.fossey@unesp.br
Publikováno v:
International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p12790. 14p.
Autor:
Mahoney, Oneil, Melo, Claudia, Lockhart, Anthony, Cornejal, Nadjet, Alsaidi, Sahar, Wu, Qingli, Simon, Jim, Juliani, Rodolfo, Zydowsky, Thomas M., Priano, Christine, Koroch, Adolfina, Fernández Romero, José A.
Publikováno v:
South African Journal of Botany
Plant-based compounds with antiviral properties against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been identified in Aframomum melegueta through computational models. The seed extract have been traditionally used to treat diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b48ea94ddd3944fdb588faed3479886
https://doi.org/10.1016/j.sajb.2021.12.010
https://doi.org/10.1016/j.sajb.2021.12.010
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1567-1590
HIV reverse transcriptase (RT) inhibitors are the important components of highly active antiretroviral therapies (HAARTs) for anti-HIV treatment and pre-exposure prophylaxis in clinical practice. Many RT inhibitors and their combination regimens have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef424a5c6c813905e85108700bf093a5
https://doi.org/10.1016/j.apsb.2021.11.009
https://doi.org/10.1016/j.apsb.2021.11.009
Publikováno v:
Journal of Advanced Research
Graphical abstract
Introduction Neomenthol, a cyclic monoterpenoid, is a stereoisomer of menthol present in the essential oil of Mentha spp. It is used in food as a flavoring agent, in cosmetics and medicines because of its cooling effects. Howe
Introduction Neomenthol, a cyclic monoterpenoid, is a stereoisomer of menthol present in the essential oil of Mentha spp. It is used in food as a flavoring agent, in cosmetics and medicines because of its cooling effects. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7618e7dc6e2d535e1930d5f8c2bf7d7e
https://doi.org/10.1016/j.jare.2021.06.003
https://doi.org/10.1016/j.jare.2021.06.003
Autor:
Khan, Adnan A., Khuroo, Tahir, Mohamed, Eman M, Dharani, Sathish, Canberk, Kayalar, Zhang, Xiaoyu, Sangaré, Lamba Omar, Kuttolamadom, Mathew A., Rice-Ficht, Allison C., Rahman, Ziyaur
Publikováno v:
AAPS PharmSciTech; Oct2024, Vol. 25 Issue 7, p1-14, 14p
Publikováno v:
Molecular Diversity; Oct2024, Vol. 28 Issue 5, p3215-3224, 10p
Autor:
Hunter A Hidalgo, Amy Scarborough, Zhen Li, Thomas E. Sharp, David J. Polhemus, J. Stephen Jenkins, Timothy Matsuura, Jeffery D. Schumacher, Daniel P. Kelly, David J. Lefer, Traci T. Goodchild
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • A large animal model that recapitulates the clinical heterogeneity of HFpEF has been developed. • Multiple comorbidities, including obesity, hypercholesterolemia, pre-diabetic phenotype, as well as pulmonary and
Highlights • A large animal model that recapitulates the clinical heterogeneity of HFpEF has been developed. • Multiple comorbidities, including obesity, hypercholesterolemia, pre-diabetic phenotype, as well as pulmonary and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1e0726e5da7045a1ac79cfd8108325
https://doi.org/10.1016/j.jacbts.2020.11.012
https://doi.org/10.1016/j.jacbts.2020.11.012
Autor:
Evelyn Seelow, Eberhard Hildt, Denna Tabari, Kathrin Woytinek, David Heiler Martín, Catharina Scholl, Julia C. Stingl, Mira Choi, Benjamin Schmidt, Mirco Glitscher
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 159-180 (2021)
Cellular and Molecular Gastroenterology and Hepatology : CMGH 12, 159-180 (2021). doi:10.1016/j.jcmgh.2021.02.002
Cellular and Molecular Gastroenterology and Hepatology, 12(1):159-180
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology : CMGH 12, 159-180 (2021). doi:10.1016/j.jcmgh.2021.02.002
Cellular and Molecular Gastroenterology and Hepatology, 12(1):159-180
Cellular and Molecular Gastroenterology and Hepatology
Background and aims The Hepatitis E virus hijacks the endosomal system for its release. These structures are highly dependent on cholesterol. Hence, this study investigates the impact of HEV on cholesterol-metabolism, the effect of intracellular chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f49a05084d5deba44d573f372cd16e
http://www.sciencedirect.com/science/article/pii/S2352345X21000357
http://www.sciencedirect.com/science/article/pii/S2352345X21000357
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4684-4701 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Safer and more-effective drugs are urgently needed to counter infections with the highly pathogenic SARS-CoV-2, cause of the COVID-19 pandemic. Identification of efficient inhibitors to treat and prevent SARS-CoV-2 infection i
Safer and more-effective drugs are urgently needed to counter infections with the highly pathogenic SARS-CoV-2, cause of the COVID-19 pandemic. Identification of efficient inhibitors to treat and prevent SARS-CoV-2 infection i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9bba885f52a030829148a7dd4dbf93
http://www.sciencedirect.com/science/article/pii/S2001037021003603
http://www.sciencedirect.com/science/article/pii/S2001037021003603
Autor:
Adenike Bernice-Eloise Adeoye, Joshua Iseoluwa Orege, Lanre Anthony Gbadegesin, Emmanuel Ayodeji Ayeni, Bashir Bolaji Tiamiyu, Yusuf Ajibola Ibrahim, Happiness Ijeoma Umeobi, Toluwanimi Oluwadara Akinyemi, S. B. Adeyemi, Mercy Adaramodu Oluwatoyosi, Joshua Adedeji Bolarin, Chuks Kenneth Odoh
Publikováno v:
International Immunopharmacology
Highlights • Therapeutic drugs with plausible efficacy against COVID-19 have been reviewed. • Notable drugs, antiviral compounds and natural products against COVID-19 were discussed. • Different drug administration regimens were appraised to as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db97177b787ee3a6fd80f9e40ee7e87
http://europepmc.org/articles/PMC7691844
http://europepmc.org/articles/PMC7691844