Effects of interleukin-3 and granulocyte-macrophage colony-stimulating factor on thrombopoiesis in congenital amegakaryocytic thrombocytopenia

Autor: EC Guinan, YS Lee, KD Lopez, S Kohler, DH Oette, E Bruno, H Kozakewich, DG Nathan, R Hoffman

Publikováno v: Blood. 81:1691-1698

Amegakaryocytic thrombocytopenia (AMT) is a rare and often fatal disorder of infancy and childhood presenting with isolated thrombocytopenia that progresses to marrow failure. The defect in thrombopoiesis is not well understood nor is the etiology of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f09f178f07363d7ec9f359168d85d452
https://doi.org/10.1182/blood.v81.7.1691.bloodjournal8171691

Inducing amenorrhea during bone marrow transplantation. A pilot study of leuprolide acetate

Autor: Laufer MR, Nl, Townsend, Ke, Parsons, Ka, Brody, Lr, Diller, S. Jean Emans, Ec, Guinan

Publikováno v: Europe PubMed Central

To evaluate, in a pilot study, the use and efficacy of a gonadotropin-releasing hormone (GnRH)-agonist in inducing amenorrhea in women undergoing BMT.We evaluated the use of the GnRH agonist leuprolide acetate (LA) for the induction of amenorrhea in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f428c89068bca01cfa97f9b1675c85f0
https://pubmed.ncbi.nlm.nih.gov/9336747

Bone marrow transplantation for children with myelodysplastic syndromes

Autor: EC Guinan, NJ Tarbell, R Tantravahi, HJ Weinstein

Publikováno v: Blood. 73(2)

Therapeutic options for children with de novo or secondary myelodysplastic syndromes (MDSs) are limited. We report the outcome of eight pediatric patients (median age 12 years, range 3 to 19 years) with myelodysplasia who underwent allogeneic bone ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1d588082b26c645fe90e7222599d50
https://pubmed.ncbi.nlm.nih.gov/2644982

Allostimulation leads to emergence of a human B cell population with increased expression of HLA class I antigen presentation-associated molecules and the immunoglobulin receptor FcRL5.

Autor: Bhatia U; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Department of Radiation Oncology, Harvard Medical School, Boston, Massachusetts, USA., Tadman S; Department of Experimental Medicine, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Rocha A; Department of Experimental Medicine, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Rudraboina R; Department of Experimental Medicine, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Contreras-Ruiz L; Department of Experimental Medicine, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Guinan EC; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Department of Radiation Oncology, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: eva_guinan@dfci.harvard.edu.

Publikováno v: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2024 Nov; Vol. 24 (11), pp. 1968-1978. Date of Electronic Publication: 2024 Jul 09.

Expanded HCT-CI Definitions Capture Comorbidity Better for Younger Patients of Allogeneic HCT for Nonmalignant Diseases.

Autor: Broglie L; CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin; Division of Pediatric Hematology/Oncology/Blood and Marrow Transplant, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin., Friend BD; Baylor College of Medicine, Center for Cell and Gene Therapy, Houston, Texas., Chhabra S; CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin; Division of Hematology/Oncology, Department of Medicine, Mayo Clinic Arizona, Phoenix, Arizona. Electronic address: Chhabra.Saurabh@mayo.edu., Logan BR; Division of Biostatistics, Institute for Health and Equity, Medical College of Wisconsin, Milwaukee, Wisconsin; CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin., Bupp C; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, Minnesota., Schiller G; Hematological Malignancy/Stem Cell Transplant Program, David Geffen School of Medicine at UCLA, Los Angeles, California., Savani BN; Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Stadtmauer E; University of Pennsylvania Abramson Cancer Center, Philadelphia, Pennsylvania., Abraham AA; Center for Cancer and Immunology Research, Division of Blood and Marrow Transplantation, Children's National Hospital, Washington, District of Columbia., Aljurf M; Department of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh, Saudi Arabia., Badawy SM; Division of Hematology, Oncology and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Illinois; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Perez MAD; Department of Hematology/Oncology, Hospital Infantil Universitario Niño Jesus, Madrid, Spain., Guinan EC; Departments of Pediatric and Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Hashem H; Division of Pediatric Hematology/Oncology and Bone Marrow Transplantation, King Hussein Cancer Center, Amman, Jordan., Krem MM; Kansas City VA Medical Center, Kansas City, Missouri., Lazarus HM; University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio., Rotz SJ; Department of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, Cleveland Clinic Children's Hospital, Cleveland, Ohio., Wirk B; Bone Marrow Transplant Program, Penn State Cancer Institute, Hershey, Pennsylvania., Yared JA; Transplantation & Cellular Therapy Program, Division of Hematology/Oncology, Department of Medicine, Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland., Pasquini M; CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin., Thakar MS; Clinical Research Division, Fred Hutchinson Cancer Center, University of Washington, Seattle, Washington; Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington., Sorror ML; Clinical Research Division, Fred Hutchinson Cancer Center, University of Washington, Seattle, Washington; Division of Medical Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington.

Publikováno v: Transplantation and cellular therapy [Transplant Cell Ther] 2023 Feb; Vol. 29 (2), pp. 125.e1-125.e9. Date of Electronic Publication: 2022 Nov 25.