Zobrazeno 1 - 10
of 16
pro vyhledávání: '"EBRU COSKUN"'
Autor:
Lingqi Meng, Han Jin, Burak Yulug, Ozlem Altay, Xiangyu Li, Lutfu Hanoglu, Seyda Cankaya, Ebru Coskun, Ezgi Idil, Rahim Nogaylar, Ahmet Ozsimsek, Saeed Shoaie, Hasan Turkez, Jens Nielsen, Cheng Zhang, Jan Borén, Mathias Uhlén, Adil Mardinoglu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Alzheimer’s disease (AD) is a debilitating neurodegenerative disorder with a global impact, yet its pathogenesis remains poorly understood. While age, metabolic abnormalities, and accumulation of neurotoxic substances are potential risk fa
Externí odkaz:
https://doaj.org/article/39a09c10d79c4cb7af897566df85c1bc
Autor:
Burak Yulug, Ozlem Altay, Xiangyu Li, Lutfu Hanoglu, Seyda Cankaya, Simon Lam, Halil Aziz Velioglu, Hong Yang, Ebru Coskun, Ezgi Idil, Rahim Nogaylar, Ahmet Ozsimsek, Cemil Bayram, Ismail Bolat, Sena Oner, Ozlem Ozdemir Tozlu, Mehmet Enes Arslan, Ahmet Hacimuftuoglu, Serkan Yildirim, Muhammad Arif, Saeed Shoaie, Cheng Zhang, Jens Nielsen, Hasan Turkez, Jan Borén, Mathias Uhlén, Adil Mardinoglu
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-23 (2023)
Abstract Background Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model and observed that CMA improve
Externí odkaz:
https://doaj.org/article/278f5ef5f370458b8e4a1065e71e2ca4
Autor:
Martin Neumann, Ebru Coskun, Lars Fransecky, Liliana H Mochmann, Isabelle Bartram, Nasrin Farhadi Sartangi, Sandra Heesch, Nicola Gökbuget, Stefan Schwartz, Christian Brandts, Cornelia Schlee, Rainer Haas, Ulrich Dührsen, Martin Griesshammer, Hartmut Döhner, Gerhard Ehninger, Thomas Burmeister, Olga Blau, Eckhard Thiel, Dieter Hoelzer, Wolf-Karsten Hofmann, Claudia D Baldus
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53190 (2013)
Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) has been identified as high-risk subgroup of acute T-lymphoblastic leukemia (T-ALL) with a high rate of FLT3-mutations in adults. To unravel the underlying pathomechanisms and the clinical
Externí odkaz:
https://doaj.org/article/040cc6f87c934f5baacf5ee661c2a9c8
Autor:
Paul Schossig, Ebru Coskun, Ruza Arsenic, David Horst, Jalid Sehouli, Eva Bergmann, Nadine Andresen, Christian Sigler, Antonia Busse, Ulrich Keller, Sebastian Ochsenreither
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2292
Volume 24
Issue 3
Pages: 2292
Adoptive T cell-receptor therapy (ACT) could represent a promising approach in the targeted treatment of epithelial ovarian cancer (EOC). However, the identification of suitable tumor-associated antigens (TAAs) as targets is challenging. We identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe982916df9ddba8bafcd00bb4a7f20
Autor:
Hasan Turkez, Ozlem Altay, Serkan Yildirim, Xiangyu Li, Hong Yang, Cemil Bayram, Ismail Bolat, Sena Oner, Ozlem Ozdemir Tozlu, Mehmet Enes Arslan, Muhammad Arif, Burak Yulug, Lutfu Hanoglu, Seyda Cankaya, Simon Lam, Halil Aziz Velioglu, Ebru Coskun, Ezgi Idil, Rahim Nogaylar, Ahmet Ozsimsek, Ahmet Hacimuftuoglu, Saeed Shoaie, Cheng Zhang, Jens Nielsen, Jan Borén, Mathias Uhlén, Adil Mardinoglu
Background: Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's disease (PD), are associated with metabolic abnormalities. Integrative analysis of human clinical data and animal studies have contributed to a better u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9959ddd342d44b0530b712aa0c90fe61
https://hdl.handle.net/20.500.12511/10251
https://hdl.handle.net/20.500.12511/10251
Autor:
BURAK YULUG, OZLEM ALTAY, XIANGYU LI, LUTFU HANOGLU, SEYDA CANKAYA, SIMON LAM, HALIL AZIZ VELIOGLU, HONG YANG, EBRU COSKUN, EZGI IDIL, RAHIM NOGAYLAR, AHMET OZSIMSEK, CEMIL BAYRAM, ISMAIL BOLAT, SENA ONER, OZLEM OZDEMIR TOZLU, MEHMET ENES ARSLAN, AHMET HACIMUFTUOGLU, SERKAN YILDIRIM, MUHAMMAD ARIF, SAEED SHOAIE, CHENG ZHANG, JENS NIELSEN, HASAN TURKEZ, JAN BOREN, MATHIAS UHLEN, Adil Mardinoglu
Background: Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administrated Combined Metabolic Activators (CMA) to the AD rat model and observed that administration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb1fc5a8f0a901fdc15d843d6ceecf34
https://doi.org/10.21203/rs.3.rs-1965067/v1
https://doi.org/10.21203/rs.3.rs-1965067/v1
Autor:
Mathias Uhlén, Adil Mardinoglu, Jan Borén, Seyda Cankaya, Simon Lam, Ebru Coskun, Rahim Nogaylar, Xiangyu Li, Lutfu Hanoglu, Hasan Turkez, Ezgi İdil, Ahmet Hacimuftuoglu, Cheng Zhang, Jens Nielsen, Ozlem Altay, Burak Yulug, Saeed Shoaie, Muhammad Arif, Hong Yang
The neuropathologic hallmarks of Parkinson’s disease (PD) are associated with mitochondrial dysfunction and metabolic abnormalities. We have reported that the Combined Metabolic Activators (CMA), consisting of L-serine, nicotinamide riboside, N-ace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85e37aa0018238ae7252c7f28aa8924e
https://doi.org/10.1101/2021.07.28.21261293
https://doi.org/10.1101/2021.07.28.21261293
Autor:
Mehmet Yalçın Günal, Seyda Cankaya, Lütfü Hanoğlu, Muzaffer Beyza Ozansoy, Zübeyir Bayraktaroğlu, Burak Yuluğ, Mehmet Ozansoy, Ebru Coskun
Publikováno v:
Acta Medica Alanya. 3:135-140
Aim: Neurodegeneration caused by the axonal injury is a widely seen phenomenon in spinal cord and traumatic brain injuries. Due to the disintegration of the synaptic connection neurotrophic factors could not be transported retrogradely towards the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdab95bf0e34c6ef323b9d415cd0d4d1
https://doi.org/10.30565/medalanya.553846
https://doi.org/10.30565/medalanya.553846
Autor:
Ismail Bolat, Seyda Cankaya, Simon Lam, Cheng Zhang, Ahmet Hacimuftuoglu, Jan Borén, Rahim Nogaylar, sena oner, Özlem Özdemir Tozlu, Saeed Shoaie, Mehmet Arslan, Jens C. O. Nielsen, Ozlem Altay, Mathias Uhlén, Muhammad Arif, Ezgi İdil, Cemil Bayram, Hasan Turkez, Ebru Coskun, Xiangyu Li, Burak Yulug, Lutfu Hanoglu, Hong Yang, Adil Mardinoglu, Serkan Yildirim
Publikováno v:
SSRN Electronic Journal.
Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. Here, we analysed the brain transcriptomics data of more than 600 AD patients using genome-scale metabolic models and provided sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12395d82b2017c7da401733eacc3b36a
https://doi.org/10.2139/ssrn.3924201
https://doi.org/10.2139/ssrn.3924201
Autor:
Dieter Hoelzer, Martin Neumann, Claudia D. Baldus, Ebru Coskun, Cornelia Schlee, Frauke Liebertz, Sandra Heesch, Nicola Goekbuget
Publikováno v:
Leukemia Research. 37:647-656
Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) has been identified as high-risk subgroup in acute T-cell lymphoblastic leukemia (T-ALL). To investigate the immature and myeloid nature of ETP-ALL we examined global microRNA (miRNA) expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bd3b8f9c440bac309e0b4cfb5110d5
https://doi.org/10.1016/j.leukres.2013.02.019
https://doi.org/10.1016/j.leukres.2013.02.019