Optimisation of BMP-2 dosage for the osseointegration of porous titanium implants in an ovine model

Autor: EB Hunziker, J Jovanovic, A Horner, MJB Keel, K Lippuner, N Shintani

Publikováno v: European Cells & Materials, Vol 32, Pp 241-256 (2016)

In clinical orthopaedics, total joint replacements and spinal fusions are routine undertakings. Many of the implicated patients suffer from osteoporosis, severe arthrosis or osteopaenia. In individuals thus afflicted, the bony bed lacks the mechanica

Externí odkaz: https://doaj.org/article/f8e098b9a1384f23b613cddb48430274

VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo

Autor: E Wernike, M-O Montjovent, Y Liu, D Wismeijer, EB Hunziker, K-A Siebenrock, W Hofstetter, FM Klenke

Publikováno v: European Cells & Materials, Vol 19, Pp 30-40 (2010)

Bone formation and osseointegration of biomaterials are dependent on angiogenesis and vascularization. Angiogenic growth factors such as vascular endothelial growth factor (VEGF) were shown to promote biomaterial vascularization and enhance bone form

Externí odkaz: https://doaj.org/article/80e385b558984a56b4b5ebce2b88a832

In major joint diseases the human synovium retains its potential to form repair cartilage.

Autor: Hunziker EB; Departments of Osteoporosis and Orthopaedic Surgery, Inselspital Bern University Hospital, Freiburgstrasse 3, 3010, Bern, Switzerland. ernst.hunziker@dbmr.unibe.ch., Shintani N; Department of Osteoporosis, Inselspital Bern University Hospital, Bern, Switzerland., Lippuner K; Department of Osteoporosis, Inselspital Bern University Hospital, Bern, Switzerland., Vögelin E; Departments of Plastic and Hand Surgery, Inselspital Bern University Hospital, Bern, Switzerland., Keel MJB; Trauma Center Hirslanden, Clinic Hirslanden, Zurich, Switzerland.; Medical School, University of Zurich, Zurich, Switzerland.; Department of Orthopaedic Surgery, Inselspital Bern University Hospital, Bern, Switzerland.

Publikováno v: Scientific reports [Sci Rep] 2023 Jun 26; Vol. 13 (1), pp. 10375. Date of Electronic Publication: 2023 Jun 26.

Crystalline Biomimetic Calcium Phosphate Coating on Mini-Pin Implants to Accelerate Osseointegration and Extend Drug Release Duration for an Orthodontic Application.

Autor: Li M; Department of Oral Cell Biology, Academic Centre of Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The Netherlands., Wu G; Department of Oral Cell Biology, Academic Centre of Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The Netherlands., Wang M; Department of Oral Cell Biology, Academic Centre of Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The Netherlands., Hunziker EB; Centre of Regenerative Medicine for Skeletal Tissues, Department of Clinical Research, University of Bern, 3010 Bern, Switzerland.; Group for Bone Biology, Department of Clinical Research, University of Bern, 3010 Bern, Switzerland., Liu Y; Department of Oral Cell Biology, Academic Centre of Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The Netherlands.

Publikováno v: Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2022 Jul 16; Vol. 12 (14). Date of Electronic Publication: 2022 Jul 16.

Induced Experimental Peri-Implantitis and Periodontitis: What Are the Differences in the Inflammatory Response?

Autor: Huang H; Department of Oral Implantology and Prosthetic Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije University Amsterdam, Amsterdam, Nord-Holland, the Netherlands., Chen D; State Key Laboratory of Basic Science of Stomatology, Laboratory of Oral Biomedicine, School and Hospital of Stomatology, Wuhan University, Wuhan, China., Lippuner K; Department of Osteoporosis, Inselspital Bern University Hospital, Bern, Switzerland., Hunziker EB; Department of Osteoporosis, Inselspital Bern University Hospital, Bern, Switzerland.; Department of Orthopaedic Surgery, Inselspital Bern University Hospital, Bern, Switzerland.

Publikováno v: The Journal of oral implantology [J Oral Implantol] 2021 Oct 01; Vol. 47 (5), pp. 359-369.