Expression and function of a receptor for hyaluronan-mediated motility on normal and malignant B lymphocytes

Autor: EA Turley, AJ Belch, S Poppema, LM Pilarski

Publikováno v: Blood. 81(2)

Migration through extracellular matrix is fundamental to malignant invasion. A receptor for hyaluronan-mediated motility (RHAMM) has previously been shown to play a fundamental role in locomotion of ras- transformed cells as well as functioning in si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9263068b81440c8d280e765d387c901d
https://pubmed.ncbi.nlm.nih.gov/7678518

CD44 and RHAMM Are Microenvironmental Sensors with Dual Metastasis Promoter and Suppressor Functions.

Autor: Tolg C; Cancer Research Laboratory Program, Lawson Health Research Institute, Victoria Hospital, London, ON, N6A 5W9, Canada., Hill KA; Department of Biology, Western University, London, ON, N6A 3K7, Canada., Turley EA; Cancer Research Laboratory Program, Lawson Health Research Institute, Victoria Hospital, London, ON, N6A 5W9, Canada.; Departments of Oncology, Biochemistry, and Surgery, Western University, London, ON, N6A 5W9, Canada.

Publikováno v: Advanced biology [Adv Biol (Weinh)] 2024 Jun; Vol. 8 (6), pp. e2300693. Date of Electronic Publication: 2024 Apr 18.

Receptor for hyaluronan-mediated motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients.

Autor: Tarullo SE; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., He Y; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Daughters C; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Knutson TP; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA., Henzler CM; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA., Price MA; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Shanley R; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Witschen P; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Tolg C; London Health Sciences Center, Western University, Ontario, Canada., Kaspar RE; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Hallstrom C; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Gittsovich L; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Sulciner ML; School of Medicine, University of Minnesota, Minneapolis, MN, USA., Zhang X; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Forster CL; Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN, USA., Lange CA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Shats O; Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE, USA., Desler M; Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE, USA., Cowan KH; Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE, USA., Yee D; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Schwertfeger KL; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Turley EA; London Health Sciences Center, Western University, Ontario, Canada., McCarthy JB; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Nelson AC; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.

Publikováno v: The Journal of pathology [J Pathol] 2023 Jul; Vol. 260 (3), pp. 289-303. Date of Electronic Publication: 2023 Apr 26.

Hyaluronan Functions in Wound Repair That Are Captured to Fuel Breast Cancer Progression.

Autor: Tolg C; London Regional Cancer Program, Lawson Health Research Institute, London, ON N6A 5W9, Canada., Messam BJ; Department Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada., McCarthy JB; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA., Nelson AC; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Turley EA; London Regional Cancer Program, Lawson Health Research Institute, Department Oncology, Biochemistry and Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada.

Publikováno v: Biomolecules [Biomolecules] 2021 Oct 20; Vol. 11 (11). Date of Electronic Publication: 2021 Oct 20.

Function-Blocking RHAMM Peptides Attenuate Fibrosis and Promote Antifibrotic Adipokines in a Bleomycin-Induced Murine Model of Systemic Sclerosis.

Autor: Wu KY; Division of Plastic and Reconstructive Surgery, Western University, London, Ontario, Canada., Kim S; Division of Plastic and Reconstructive Surgery, Western University, London, Ontario, Canada; Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Liu VM; Department of Biochemistry, Western University, London, Ontario, Canada., Sabino A; Department of Life Sciences, Queen's University, Kingston, Ontario, Canada., Minkhorst K; Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Yazdani A; Division of Plastic and Reconstructive Surgery, Western University, London, Ontario, Canada., Turley EA; London Regional Cancer Program, London Health Sciences Centre, London, Ontario, Canada. Electronic address: eva.turley@lhsc.on.ca.

Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2021 Jun; Vol. 141 (6), pp. 1482-1492.e4. Date of Electronic Publication: 2020 Nov 23.