S44 Repair of acute respiratory distress syndrome in COVID-19 by stromal cells (REALIST-COVID trial): 1 year follow up for safety and pulmonary dysfunction

Autor: HJ Gardiner, EA Gorman, AJ Rostron, M Shankar-Hari, J Bannard-Smith, AM Bentley, D Brealey, C Campbell, G Curley, M Clarke, A Dushianthan, P Hopkins, C Jackson, K Kefela, JG Laffey, C McDowell, M McFarland, J McFerran, P McGuigan, GD Perkins, J Silversides, J Smythe, J Thompson, WS Tunnicliffe, IDM Welters, B Williams, DF McAuley, CM O’Kane

Publikováno v: ‘The fast and the furious’ – Clinical studies in COVID-19.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::180719adba23ed4cef1bdc1f15d777a2
https://doi.org/10.1136/thorax-2022-btsabstracts.50

P23 The incidence of congenital thoracic malformations: an increasing trend from 1994 to 2011 in a defined population

Autor: EA Gorman, S Thavagnanam, J Houton, A Dick, A Patterson, MD Shields

Publikováno v: Thorax. 68:A84.2-A85

Introduction Congenital thoracic malformations (CTMs) are an uncommon heterogenous group of disorders including congenital cystic adenomatous malformation (CCAM), pulmonary sequestration (PS), congenital lobar overinflation (CLO), hybrid lesions and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2d42bf271a4cf8b3d7fe9f3a149fe02
https://doi.org/10.1136/thoraxjnl-2013-204457.173

Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial): A Multicenter, Randomized, Controlled Clinical Trial.

Autor: Gorman EA; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom., Rynne J; Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United Kingdom., Gardiner HJ; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom., Rostron AJ; Sunderland Royal Hospital, South Tyneside and Sunderland National Health Service Foundation Trust, Sunderland, United Kingdom.; Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Bannard-Smith J; Department of Critical Care, Manchester Royal Infirmary, Manchester, United Kingdom., Bentley AM; Acute Intensive Care Unit, Wythenshawe Hospital, Manchester, United Kingdom., Brealey D; University College Hospital London, London, United Kingdom., Campbell C; Northern Ireland Clinical Trials Unit, Belfast, United Kingdom., Curley G; Royal College of Surgeons in Ireland, Dublin, Ireland., Clarke M; Northern Ireland Clinical Trials Unit, Belfast, United Kingdom., Dushianthan A; University Hospital Southampton, Southampton, United Kingdom.; National Institute for Health and Care Research Southampton Biomedical Research Centre, University of Southampton, Southampton, United Kingdom., Hopkins P; King's Trauma Centre, King's College Hospital, London, United Kingdom., Jackson C; Northern Ireland Clinical Trials Unit, Belfast, United Kingdom., Kefela K; Department of Critical Care, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom., Krasnodembskaya A; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom., Laffey JG; Regenerative Medicine Institute at CÚRAM Centre for Research in Medical Devices, University of Galway, Galway, Ireland., McDowell C; Northern Ireland Clinical Trials Unit, Belfast, United Kingdom., McFarland M; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom., McFerran J; Northern Ireland Clinical Trials Unit, Belfast, United Kingdom., McGuigan P; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom., Perkins GD; Critical Care Unit, University Hospitals Birmingham, Birmingham, United Kingdom.; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, United Kingdom., Silversides J; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom., Smythe J; National Health Service Blood and Transplant, Oxford, United Kingdom., Thompson J; National Health Service Blood and Transplant, Birmingham, United Kingdom., Tunnicliffe WS; Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom., Welters IDM; Intensive Care Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.; Institute of Life Course Medical Sciences, University of Liverpool, Liverpool Centre for Cardiovascular Science, Liverpool, United Kingdom., Amado-Rodríguez L; Centro de Investigación Biomédica en Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.; Unidad de Cuidados Intensivos Cardiológicos, Hospital Universitario Central de Asturias, Oviedo, Spain., Albaiceta G; Centro de Investigación Biomédica en Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.; Unidad de Cuidados Intensivos Cardiológicos, Hospital Universitario Central de Asturias, Oviedo, Spain.; Departamento de Biología Funcional, Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, Oviedo, Spain; and., Williams B; Independent Patient and Public Representative, Sherborne, United Kingdom., Shankar-Hari M; Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United Kingdom., McAuley DF; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom., O'Kane CM; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2023 Aug 01; Vol. 208 (3), pp. 256-269.

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial.

Autor: Perkins GD; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Ji C; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Connolly BA; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland.; Lane Fox Clinical Respiratory Physiology Research Centre, Guy's and St Thomas' NHS Foundation Trust, London, England.; Centre for Human and Applied Physiological Sciences, King's College London, London, England.; Department of Physiotherapy, University of Melbourne, Melbourne, Australia., Couper K; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Lall R; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Baillie JK; Roslin Institute, University of Edinburgh, Midlothian, Scotland.; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, Scotland., Bradley JM; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland., Dark P; NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, England.; Salford Royal Hospital, Northern Care Alliance NHS Group, Manchester, England., Dave C; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., De Soyza A; Population and Health Science Institute, NIHR Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, England.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England., Dennis AV; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Devrell A; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England.; Research Champion Team, West Midlands Clinical Research Network, Wolverhampton, England., Fairbairn S; Grange University Hospital, Aneurin Bevan University Health Board, Cwmbran, Wales., Ghani H; Watford General Hospital, West Hertfordshire Hospitals NHS Trust, Watford, England., Gorman EA; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland., Green CA; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Hart N; Lane Fox Clinical Respiratory Physiology Research Centre, Guy's and St Thomas' NHS Foundation Trust, London, England.; Centre for Human and Applied Physiological Sciences, King's College London, London, England., Hee SW; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, England., Kimbley Z; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Madathil S; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., McGowan N; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Messer B; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England., Naisbitt J; Fairfield General Hospital, Pennine Acute Hospitals NHS Trust, Northern Care Alliance NHS Group, Bury, England., Norman C; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Parekh D; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England.; Institute of Inflammation and Ageing, School of Medical and Dental Sciences, University of Birmingham, Birmingham, England., Parkin EM; Fairfield General Hospital, Pennine Acute Hospitals NHS Trust, Northern Care Alliance NHS Group, Bury, England., Patel J; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England.; Institute of Inflammation and Ageing, School of Medical and Dental Sciences, University of Birmingham, Birmingham, England., Regan SE; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Ross C; Imperial College Healthcare NHS Trust, London, England., Rostron AJ; Sunderland Royal Hospital, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, England.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, England., Saim M; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Simonds AK; Royal Brompton and Harefield Hospital, Guy's and St Thomas' NHS Foundation Trust, London, England., Skilton E; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Stallard N; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, England., Steiner M; Institute for Lung Health, NIHR Leicester Biomedical Research Centre, Department of Respiratory Sciences, University of Leicester, Leicester, England., Vancheeswaran R; Watford General Hospital, West Hertfordshire Hospitals NHS Trust, Watford, England., Yeung J; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., McAuley DF; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland.; Royal Victoria Hospital, Belfast, Northern Ireland.

Publikováno v: JAMA [JAMA] 2022 Feb 08; Vol. 327 (6), pp. 546-558.